Drug & supplement interaction

American Ginseng + Inhaled Insulin

Inhaled Insulin brand name: Exubera.

Moderate Interaction
Medically reviewed by · Updated September 2026
The bottom line Moderate

American Ginseng has a moderate interaction with Inhaled Insulin. Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.

Read the full interaction report
SeverityModerate
LikelihoodProbable
EvidenceB
What do Severity, Likelihood & Evidence mean?
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Interaction report

American Ginseng and Inhaled Insulin

Here is the interaction we found between these two, with the evidence behind it.

Moderate

ANTIDIABETES DRUGS

Why this applies to Inhaled Insulin

Inhaled Insulin falls under ANTIDIABETES DRUGS — the group American Ginseng interacts with.

Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
American ginseng seems to lower postprandial blood glucose. Theoretically, concomitant use with antidiabetes drugs might enhance blood glucose lowering effects and possibly cause hypoglycemia.
Severity Moderate Likelihood Probable Evidence B

Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports..

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the simple version: American ginseng appears to nudge your blood sugar down a bit, especially after meals. Inhaled insulin (Exubera) is a fast-acting insulin you breathe in at mealtimes, and its whole job is to lower blood sugar too. Stack the two together and you could push your numbers lower than you intended, which raises the chance of a low blood sugar (hypoglycemia) episode.

Watch for the usual lows: shakiness, sweating, a racing heart, dizziness, confusion, or sudden hunger. The good news is this concern is mostly theoretical and based on limited research, and small amounts in food likely won't matter much. Still, if you want to try a ginseng supplement, check in with your doctor or pharmacist first so they can help you monitor your sugars. Please don't change your insulin dose on your own.

Contact Dr. Brian directly if you have additional questions on this interaction
References
  1. Vuksan V, Sievenpiper JL, Koo VY, et al. American ginseng (Panax quinquefolius L) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus. Arch Intern Med 2000;160:1009-13. PubMed
  2. Vuksan V, Stavro MP, Sievenpiper JL, et al. Similar postprandial glycemic reductions with escalation of dose and administration time of American ginseng in type 2 diabetes. Diabetes Care 2000;23:1221-6. PubMed

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

American Ginseng Also Interacts With Other Medications

American Ginseng has 2 major, 214 moderate known drug interactions in our database — the Inhaled Insulin one above is one of them. If you take anything else, check it against the full list below.

Major 2 Moderate 214 No known interaction 2,614 (incl. Inhaled Insulin)
Taking anything else?

Check Another of Your Medications Against American Ginseng

Covers the 2,830 medications we’ve checked against American Ginseng. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Inhaled Insulin

This page covers American Ginseng only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Inhaled Insulin page lists 259 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Chelation Therapy Products (major), Siberian Cocklebur (major), Acai (moderate) and African Wild Potato (moderate).

By severity: 3 major · 218 moderate · 38 minor.

From our pharmacist’s overview on the Inhaled Insulin page

“Inhaled insulin (Exubera) comes with a supplement list that warrants real caution, and the three major-rated entries deserve your attention first. Siberian cocklebur has caused severe hypoglycemia in people, activated charcoal can pull medications out of the body, and chelation products containing EDTA can drive blood sugar dangerously…”

Reviewed by 2 · Jul 18, 2026

Open the Inhaled Insulin interaction page

One more smart check

Taking American Ginseng as Part of a Dietary Supplement Product? Check It for Interactions

We hold 992 real supplement products containing American Ginseng, each one broken down to its full ingredient list — and combination products often carry several ingredients besides American Ginseng. Your product may carry other ingredients that interact with Inhaled Insulin too, on top of American Ginseng — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where American Ginseng and Inhaled Insulin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement American Ginseng
Top 25%

#217 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Inhaled Insulin
Top 25%

#676 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About American Ginseng

What is American Ginseng?

American Ginseng
  • Stress and energy support
  • Immune support and colds
  • Blood sugar management
  • Mental focus and clarity
  • General wellness (adaptogen)

American ginseng is an herbal root used as an 'adaptogen' to support energy, stress, immune function, and blood sugar. Some uses—such as reducing the chance or length of colds and modestly lowering after-meal blood sugar—have early supportive evidence, but most claims are not well proven. Talk to your pharmacist or doctor before use, especially if you have a health condition or take medications.

Read the full American Ginseng monograph & all interactions
Keep checking

Other Drugs & American Ginseng

Browse every other medication we’ve checked against American Ginseng — both the ones with a known interaction and the ones without. Select any drug for the full detail.

2Major
214Moderate
0Minor
2,613No known interaction
2 Major 214 Moderate 2,613 No interaction
Major

2 interactions

Moderate

214 interactions

Showing 60 of 214 moderate interactions — see all 214 on the American Ginseng page.

No interaction 2,613 drugs checked — show the list

We also checked American Ginseng against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,613 medications checked with no known interaction — see the full American Ginseng list.

See the full American Ginseng interactions page
See every supplement checked against Inhaled Insulin, ranked by severity
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
American Ginseng monograph › Uses, safety, and every drug interaction in one place Inhaled Insulin supplement interactions › Every supplement checked against Inhaled Insulin, ranked by severity Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking American Ginseng and Inhaled Insulin Together: Common Questions

Can you take American Ginseng with Inhaled Insulin?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the American Ginseng and Inhaled Insulin interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Inhaled Insulin and American Ginseng?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.