Drug & supplement interaction

Asparagus Racemosus + Ospemifene

Ospemifene brand name: Osphena.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Asparagus Racemosus and Ospemifene in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Ospemifene states a food rule worth keeping to.

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Interaction report

Asparagus Racemosus and Ospemifene

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ospemifene and Asparagus Racemosus in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Asparagus Racemosus safety at a glance

Asparagus Racemosu... overall Use caution Generally considered well tolerated in traditional use, but high-quality safety data are limited.
Pregnancy Avoid Safety during pregnancy is not well established, so it is best avoided unless a doctor advises otherwise.
Breastfeeding Use caution It is traditionally used to support milk supply, but reliable safety data are lacking, so use only under professional guidance.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ospemifene and Asparagus Racemosus? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Ospemifene

Interactions in our licensed database are recorded against drug classes, not just single drug names. Ospemifene is filed under 3 classifications — thyroid hormone, cytochrome p450 3a4 (cyp3a4) substrates, oral drugs. Asparagus Racemosus has documented interactions with 2 drug classes — the most serious being diuretic drugs (moderate) and lithium (moderate) — and none of Ospemifene’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Asparagus Racemosus Does Interact With Other Medications

Asparagus Racemosus has 76 moderate known drug interactions in our database — Ospemifene isn’t one of them. If you take anything else, check it against the full list below.

Moderate 76 No known interaction 2,754 (incl. Ospemifene)
Taking anything else?

Check Another of Your Medications Against Asparagus Racemosus

Covers the 2,830 medications we’ve checked against Asparagus Racemosus. Pick one to open its full report.

What to actually watch for

What Ospemifene’s Own FDA Label Lists

This is not an interaction — none of it involves Asparagus Racemosus. These are the most notable effects listed in the ADVERSE REACTIONS section of Ospemifene’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 6 of them are worth acting on rather than waiting out — marked below.

  • A stroke or mini-stroke Worth acting on
  • Blood clots Worth acting on
  • Bleeding or bruising Worth acting on mentioned in 5.8% of FDA reports for Ospemifene
  • A severe allergic reaction Worth acting on
  • Hives Worth acting on
  • An allergic reaction Worth acting on
  • Flushing mentioned in 14.3% of FDA reports for Ospemifene
  • Muscle pain mentioned in 7.5% of FDA reports for Ospemifene
  • Sweating
  • Itching

Showing the 10 most notable of 12 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Ospemifene. Read the label on DailyMed › Where a percentage is shown, it is the share of 2,601 voluntary FDA FAERS reports for Ospemifene that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Asparagus Racemosus’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Asparagus Racemosus side to compare — that is a limit of the record, not a statement that Asparagus Racemosus has no side effects.

How to take them

Some Ospemifene Products Have a Food Rule — Asparagus Racemosus Should Not Break It

At least one FDA label for a product containing Ospemifene says to take it with food. If you take Asparagus Racemosus on an empty stomach out of habit, keep them separate — and take Ospemifene with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Ospemifene products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

One tablet taken orally once daily with food.

From the Dosage and Administration section of the FDA label we read for Ospemifene — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Ospemifene

This page covers Asparagus Racemosus only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ospemifene page lists 155 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Tiratricol (major) and Acacia Rigidula (moderate).

By severity: 4 major · 112 moderate · 39 minor.

From our pharmacist’s overview on the Ospemifene page

“Women prescribed ospemifene (Osphena) for painful intercourse after menopause are often the same women reaching for St. John's wort for mood or grapefruit juice at breakfast, and both sit among the four major-rated interactions on this page, so the list deserves genuine care.”

Reviewed by 2 · Jul 18, 2026

Open the Ospemifene interaction page

One more smart check

Taking Asparagus Racemosus as Part of a Dietary Supplement Product? Check It for Interactions

We hold 330 real supplement products containing Asparagus Racemosus, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Asparagus Racemosus. Even though Asparagus Racemosus itself has no known interaction with Ospemifene, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Asparagus Racemosus and Ospemifene Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Asparagus Racemosus
Top 25%

#357 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ospemifene
Steady interest

#2,417 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Asparagus Racemosus reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Asparagus Racemosus and Ospemifene records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Asparagus Racemosus

What is Asparagus Racemosus?

Asparagus Racemosus
  • Women's reproductive health
  • Promoting breast milk supply
  • Digestive complaints
  • General tonic and stress support
  • Menopausal symptoms

Asparagus racemosus, often called shatavari, is an Ayurvedic herb traditionally used to support women's health, digestion, and overall vitality. Human evidence for most of these uses is limited and preliminary, so benefits are not well proven. Talk with your pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have hormone-sensitive conditions.

Asparagus racemosus · Asparagaceae · Roots (tuberous roots) · Capsules, tablets, powder (churna), liquid extracts, syrups

An interaction check asks whether these two react with each other — it does not ask whether Asparagus Racemosus is a good idea for someone in your situation. Here is what our Asparagus Racemosus record says about it on its own.

Asparagus Racemosus: dosing

There is no official, standardized dose for Asparagus racemosus. Products vary widely in strength and form, from powders to capsules to liquid extracts.The best approach is to follow the directions on the product label and not exceed the recommended amount.

From our Asparagus Racemosus monograph — the full record covers uses, side effects and every documented interaction.

Read the full Asparagus Racemosus monograph & all interactions
Medication

About Ospemifene

What Is Ospemifene Used For?

Brand name: Osphena

Osphena (ospemifene) is used to treat two specific symptoms of vulvar and vaginal atrophy — the thinning and drying of vaginal tissues that can happen after menopause. The first is moderate to severe dyspareunia (painful intercourse), and the second is moderate to severe vaginal dryness.

Both of these uses are for postmenopausal women only. Osphena is not used in children or in women who are pregnant or may become pregnant.

Most-Reported Side Effects for Ospemifene

From FAERS, the FDA’s public side-effect reporting system (2,601 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Hot flush 372 reports
Headache 209 reports
Muscle spasms 194 reports
Vaginal haemorrhage 150 reports
Vaginal discharge 134 reports
See full Ospemifene drug information
Keep checking

Other Drugs & Asparagus Racemosus

Browse every other medication we’ve checked against Asparagus Racemosus — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
76Moderate
0Minor
2,753No known interaction
76 Moderate 2,753 No interaction
Moderate

76 interactions

Showing 60 of 76 moderate interactions — see all 76 on the Asparagus Racemosus page.

No interaction 2,753 drugs checked — show the list

We also checked Asparagus Racemosus against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,753 medications checked with no known interaction — see the full Asparagus Racemosus list.

See the full Asparagus Racemosus interactions page
See every supplement checked against Ospemifene, ranked by severity
Evidence & sources

Asparagus Racemosus References

The 1 references that drive our Asparagus Racemosus monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Satish Kumar MC, Udupa AL, Sammodavardhana K, Rathnakar UP, Shvetha U, Kodancha GP. Acute toxicity and diuretic studies of the roots of Asparagus racemosus Willd in rats. West Indian Med J. 2010;59(1):3-6.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Asparagus Racemosus and Ospemifene Together: Common Questions

Is it safe to take Asparagus Racemosus with Ospemifene?
We do not list a known interaction between Asparagus Racemosus and Ospemifene. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Asparagus Racemosus and Ospemifene at the same time of day?
At least one FDA label for a product containing Ospemifene says to take it with food. If you take Asparagus Racemosus on an empty stomach out of habit, keep them separate and take Ospemifene with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Ospemifene products can differ — so check the directions on your own box. This is about absorption, not an interaction.
How was the Asparagus Racemosus and Ospemifene combination checked?
Interactions in our licensed database are recorded against drug classes. Ospemifene is filed under 3 classifications, and Asparagus Racemosus has documented interactions with 2 drug classes — none of Ospemifene's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Asparagus Racemosus interact with any other medications?
Yes. Asparagus Racemosus has 76 documented drug interactions in our database — Ospemifene is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Ospemifene interact with any supplements?
Yes. Ospemifene has documented interactions with 155 supplements in our database — Asparagus Racemosus is not one of them. The Ospemifene interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Asparagus Racemosus monograph Uses, safety profile, and every drug interaction in one place Ospemifene drug information The full plain-English guide to this medication Ospemifene supplement interactions Every supplement checked against Ospemifene, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Ospemifene and Asparagus Racemosus?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.