Avocado Soy Unsaponifiables (asu) + Pacritinib
Pacritinib brand name: Vonjo.
We found no known interaction between Avocado Soy Unsaponifiables (asu) and Pacritinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Avocado Soy Unsaponifiables (asu) and Pacritinib
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Pacritinib and Avocado Soy Unsaponifiables (asu) in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Avocado Soy Unsaponifiables (asu) at all — not against Pacritinib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Avocado Soy Unsaponifiables (asu) safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
See Every Supplement That Interacts With Pacritinib
This page covers Avocado Soy Unsaponifiables (asu) only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Pacritinib page lists 158 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).
By severity: 8 major · 110 moderate · 40 minor.
From our pharmacist’s overview on the Pacritinib page
“Someone on pacritinib (Vonjo) is usually fighting myelofibrosis, and the supplements people reach for during cancer treatment, herbal blends, immune boosters, St. John's wort for mood, are where this list gets serious.”
Reviewed by 2 · Jul 18, 2026
Where Avocado Soy Unsaponifiables (asu) and Pacritinib Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,323 of 1,452 supplements looked up here in the last 7 days
#2,475 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Avocado Soy Unsaponifiables (asu) reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Avocado Soy Unsaponifiables (asu) and Pacritinib records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Avocado Soy Unsaponifiables (asu)
What is Avocado Soy Unsaponifiables (asu)?
- Osteoarthritis of the knee and hip
- Joint pain and stiffness
- Reducing reliance on NSAIDs
- Cartilage support
- Temporomandibular joint (TMJ) discomfort
Avocado Soy Unsaponifiables (ASU) is a plant-oil extract studied mainly for osteoarthritis of the knee and hip, where some research suggests it may modestly ease pain and improve joint function. It is generally well tolerated, but the evidence is mixed and effects build slowly over months. Talk with your pharmacist or doctor before starting, especially if you take other medicines or have allergies.
Oils from avocado fruit (Persea americana) and soybean (Glycine max) · Capsules, softgels (often combined with glucosamine and chondroitin in joint supplements)
An interaction check asks whether these two react with each other — it does not ask whether Avocado Soy Unsaponifiables (asu) is a good idea for someone in your situation. Here is what our Avocado Soy Unsaponifiables (asu) record says about it on its own.
Avocado Soy Unsaponifiables (asu): dosing
There is no official standardized dose for ASU, and products can differ in strength and content. Because ASU works slowly, it may take two to three months before you can judge whether it is helping.
From our Avocado Soy Unsaponifiables (asu) monograph — the full record covers uses, side effects and every documented interaction.
About Pacritinib
What Is Pacritinib Used For?
Brand name: Vonjo
Vonjo (pacritinib) is used to treat adults with intermediate or high-risk myelofibrosis (MF) — a serious bone marrow disease — including primary MF and secondary MF that developed after polycythemia vera or essential thrombocythemia (other blood disorders). It is specifically approved for patients whose platelet count is below 50 × 10⁹/L (very low platelets), a group that has limited treatment options.
This approval is based on demonstrated reductions in spleen size. Continued approval may depend on results from confirmatory trials showing broader clinical benefit.
Other Drugs & Avocado Soy Unsaponifiables (asu)
Browse every other medication we’ve checked against Avocado Soy Unsaponifiables (asu) — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Avocado Soy Unsaponifiables (asu) against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Abemaciclib ›
- Ivermectin ›
- Testosterone ›
- Sertraline ›
- Acetaminophen ›
- Losartan Potassium ›
- Aspirin ›
- Rosuvastatin ›
- Metoprolol ›
- Escitalopram ›
- Clopidogrel ›
- Rivaroxaban ›
- Atorvastatin ›
- Isotretinoin ›
- Warfarin Sodium ›
- Tirzepatide ›
- Amlodipine Besylate ›
- Ibuprofen ›
- Methamphetamine ›
- Docusate ›
- Tadalafil ›
- Sumatriptan ›
- Valacyclovir ›
- Hydroxyurea ›
- Prednisone ›
- Amitriptyline ›
- Metformin ›
- Semaglutide ›
- Lisdexamfetamine ›
- Amphetamine ›
- Levothyroxine, Liothyronine ›
- Propranolol ›
- Methotrexate ›
- Amoxicillin ›
- Lisinopril ›
- Bupropion ›
- Fluoxetine ›
- Azithromycin ›
- Bendamustine ›
- Pregabalin ›
- Doxycycline ›
- Gabapentin ›
- Dextroamphetamine ›
- Lamotrigine ›
- Acyclovir ›
- Naproxen ›
- Acetaminophen, Aspirin, Caffeine ›
- Quetiapine ›
- Clonazepam ›
- Buspirone ›
- Omeprazole ›
- Duloxetine ›
- Letrozole ›
- Citalopram ›
- Methylene Blue ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Avocado Soy Unsaponifiables (asu) list.
Avocado Soy Unsaponifiables (asu) References
The 3 references that drive our Avocado Soy Unsaponifiables (asu) monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Maheu E, Mazieres B, Valat JP, et al. Symptomatic efficacy of avocado/soybean unsaponifiables in the treatment of osteoarthritis of the knee and hip: a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial with a six-month
- Lequesne M, Maheu E, Cadet C, Dreiser RL. Structural effect of avocado/soybean unsaponifiables on joint space loss in osteoarthritis of the hip. Arthritis Rheum 2002;47:50-8.. PubMed
- Christiansen BA, Bhatti S, Goudarzi R, Emami S. Management of osteoarthritis with avocado/soybean unsaponifiables. Cartilage. 2015;6(1):30-44. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Avocado Soy Unsaponifiables (asu) and Pacritinib Together: Common Questions
Is it safe to take Avocado Soy Unsaponifiables (asu) with Pacritinib?
Do Avocado Soy Unsaponifiables (asu) and Pacritinib have any of the same side effects?
Does Pacritinib interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.