Barley - Egaten (Triclabendazole) Interaction
Herbal: Barley
Also Known As: Hordeum vulgare
Drug: Triclabendazole
Brand names:
Egaten
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 29, 2025
Interaction Details
Triclabendazole is classified as belonging to the following category: Triclabendazole (Egaten)
Theoretically, barley might decrease the clinical effects of triclabendazole.
Animal research suggests that a diet supplemented with barley can reduce the bioavailability of triclabendazole when taken concomitantly. This effect has not been shown in humans.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Ferre, I., Giraldez, F. J., Alvarez-Bujidos, M. L., and Mantecon, A. R. Influence of barley supplement on plasma concentration of triclabendazole metabolites in sheep. Vet.Rec. 11-22-1997;141(21):549-551.
Barley Overview
Barley, a widely used grain renowned for its high fiber content, serves both as a staple food and an ingredient in brewing various types of alcoholic beverages. Research suggests that barley's dietary fiber may reduce the risk of coronary heart disease. Studies indicate that daily consumption of 3-12 grams of barley can help lower total cholesterol and LDL cholesterol levels in adults with hypercholesterolemia. A key component of barley is beta-glucans, a soluble fiber known for its health benefits. Barley also contains tocopherols and tocotrienols, forms of vitamin E with antioxidant properties that further enhance its nutritional value. Moreover, barley contains hordenine and lunasin, compounds under study for their potential health-promoting effects.
Triclabendazole Overview
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Triclabendazole is used to treat fascioliasis (an infection, usually in the liver and bile ducts, caused by flat worms [liver flukes]) in adults and children 6 years of age and older. Triclabendazole is in a class of medications called anthelmintics. It works by killing the flat worms.
Barley - More Interactions
Barley interacts with 1 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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