Beta-carotene + Rosuvastatin
Rosuvastatin brand names: Crestor, Ezallor.
We found no known interaction between Beta-carotene and Rosuvastatin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Beta-carotene and Rosuvastatin
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Rosuvastatin and Beta-carotene in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Beta-carotene safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Rosuvastatin
Interactions in our licensed database are recorded against drug classes, not just single drug names. Rosuvastatin is filed under 4 classifications — including hmg-coa reductase inhibitors ("statins"), hepatotoxic drugs, oral drugs. Beta-carotene has documented interactions with 1 drug class — the most serious being niacin (minor) — and none of Rosuvastatin’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Beta-carotene Does Interact With Other Medications
Beta-carotene has 3 minor known drug interactions in our database — Rosuvastatin isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Beta-carotene
We haven’t checked that one against Beta-carotene yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Beta-carotene. Pick one to open its full report.
Beta-carotene in Pregnancy & Breastfeeding
When used orally and appropriately. There is insufficient reliable information available about the safety of large doses of beta-carotene in pregnancy and lactation.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
What Rosuvastatin Is Prescribed For, and What Beta-carotene Has Been Studied For
These two come up together because they touch the same health topic — not because they do the same job. Rosuvastatin is a prescription medicine with approved uses on its FDA label. Beta-carotene is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.
Rosuvastatin is prescribed for: Rosuvastatin tablets are used alongside diet changes to lower LDL-C ("bad" cholesterol), total cholesterol, and triglycerides (blood fats), and to raise HDL-C ("good" cholesterol) in adults with high cholesterol or mixed cholesterol problems. They are also used in adults with very high triglycerides, a condition called primary dysbetalipoproteinemia (Type III, a genetic fat-metabolism disorder), and to slow the buildup of plaque in arteries (atherosclerosis). In people without established heart disease but with multiple risk factors, rosuvastatin tablets can reduce the risk of heart attack, stroke, and procedures to open blocked arteries. For children and teens aged 8 and older with heterozygous familial hypercholesterolemia (HeFH, an inherited high-cholesterol condition), the tablet form is used to lower LDL-C after diet alone has not worked.
Read the rest of what Rosuvastatin is prescribed for
Crestor tablets are also approved to treat homozygous familial hypercholesterolemia (HoFH, a more severe inherited form) in adults and in children aged 7 and older.
Beta-carotene has been studied for:
-
Stroke studied, not established Beta-carotene has been studied for this. Natural Medicines rates the evidence: Possibly Ineffective Read what the research shows
Beta-carotene for stroke
Oral beta-carotene does not seem to reduce stroke risk and may actually increase risk in some patients.
Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Rosuvastatin on your own; if you are taking Beta-carotene for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.
Questions About Beta-carotene or Rosuvastatin
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Beta-carotene or Rosuvastatin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
- Black Currant Oil With Levothyroxine, Methotrexate, and a Statin ›
- Can You Take Nattokinase With a 40 mg Statin? ›
- Does Zetia Cause Weight Gain Or Weight Loss? ›
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Rosuvastatin
This page covers Beta-carotene only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Rosuvastatin page lists 63 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and Wine (major).
By severity: 5 major · 48 moderate · 10 minor.
From our pharmacist’s overview on the Rosuvastatin page
“Rosuvastatin (Crestor, Ezallor) is a statin taken daily for years to lower cholesterol, and its supplement list deserves real scrutiny, not a quick skim. Five of the 63 ingredients on file carry a major rating, headed by grapefruit, which can raise statin blood levels, and by heavy drinking, since beer and wine compound the strain this…”
Reviewed by 2 · Jul 18, 2026
Taking Beta-carotene as Part of a Dietary Supplement Product? Check It for Interactions
We hold 11 real supplement products containing Beta-carotene, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Beta-carotene. Even though Beta-carotene itself has no known interaction with Rosuvastatin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Beta-carotene and Rosuvastatin Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,431 of 1,452 supplements looked up here in the last 7 days
#9 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Beta-carotene reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Beta-carotene and Rosuvastatin records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Beta-carotene
What is Beta-carotene?
- Vitamin A source
- Eye and vision health
- Antioxidant support
- Skin health
- General wellness
Beta-carotene is a plant pigment that the body can convert into vitamin A and that also acts as an antioxidant. Getting it from colorful fruits and vegetables is considered safe and healthy, but high-dose supplements have been linked to a higher lung cancer risk in smokers and people exposed to asbestos, so most people should not take large amounts.
Pigment found in colorful fruits and vegetables (carrots, sweet potatoes, leafy greens) · Capsules, softgels, tablets, multivitamins, and as a food coloring
An interaction check asks whether these two react with each other — it does not ask whether Beta-carotene is a good idea for someone in your situation. Here is what our Beta-carotene record says about it on its own.
Beta-carotene: dosing
There is no single agreed-upon supplement dose of beta-carotene for general health, and many experts recommend getting it from food rather than pills. Supplement amounts in products vary widely.If you choose to take a beta-carotene supplement, follow the directions on the product label and do not exceed the recommended amount. Avoid high doses, especially if you smoke.
From our Beta-carotene monograph — the full record covers uses, side effects and every documented interaction.
About Rosuvastatin
What Is Rosuvastatin Used For?
Brand names: Crestor, Ezallor
Rosuvastatin tablets are used alongside diet changes to lower LDL-C ("bad" cholesterol), total cholesterol, and triglycerides (blood fats), and to raise HDL-C ("good" cholesterol) in adults with high cholesterol or mixed cholesterol problems. They are also used in adults with very high triglycerides, a condition called primary dysbetalipoproteinemia (Type III, a genetic fat-metabolism disorder), and to slow the buildup of plaque in arteries (atherosclerosis).
In people without established heart disease but with multiple risk factors, rosuvastatin tablets can reduce the risk of heart attack, stroke, and procedures to open blocked arteries. For children and teens aged 8 and older with heterozygous familial hypercholesterolemia (HeFH, an inherited high-cholesterol condition), the tablet form is used to lower LDL-C after diet alone has not worked. Crestor tablets are also approved to treat homozygous familial hypercholesterolemia (HoFH, a more severe inherited form) in adults and in children aged 7 and older.
Most-Reported Side Effects for Rosuvastatin
From FAERS, the FDA’s public side-effect reporting system (229,715 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Beta-carotene
Browse every other medication we’ve checked against Beta-carotene — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
3 interactions
No interaction 2,826 drugs checked — show the list
We also checked Beta-carotene against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Escitalopram ›
- Tadalafil ›
- Acetaminophen ›
- Clopidogrel ›
- Valacyclovir ›
- Atorvastatin ›
- Docusate ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Sumatriptan ›
- Ibuprofen ›
- Semaglutide ›
- Tirzepatide ›
- Warfarin Sodium ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Acyclovir ›
- Bupropion ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Lamotrigine ›
- Fluoxetine ›
- Methotrexate ›
- Acetaminophen, Codeine ›
- Gabapentin ›
- Amphetamine ›
- Pregabalin ›
- Isotretinoin ›
- Dextroamphetamine ›
- Azithromycin ›
- Clonazepam ›
- Quetiapine ›
- Omeprazole ›
- Amlodipine Besylate ›
- Methylene Blue ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
- Naproxen ›
- Bisoprolol ›
Showing the 60 most looked-up of 2,826 medications checked with no known interaction — see the full Beta-carotene list.
Beta-carotene References
The 17 references that drive our Beta-carotene monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Tribble DL. AHA Science Advisory. Antioxidant consumption and risk of coronary heart disease: emphasis on vitamin C, vitamin E, and beta-carotene: A statement for healthcare professionals from the American Heart Association. Circulation 1999;99:591-5.
- Omenn GS, Goodman GE, Thornquist MD, et al. Effects of a combination of beta-carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med 1996;334:1150-5. PubMed
- Greenberg ER, Baron JA, Karagas MR, et al. Mortality associated with low plasma concentration of beta carotene and the effect of oral supplementation. JAMA 1996;275:699-703. PubMed
- Rapola JM, Virtamo J, Ripatti S, et al. Randomised trial of alpha-tocopherol and beta-carotene supplements on incidence of major coronary events in men with previous myocardial infarction. Lancet 1997;349:1715-20.
- The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med 1994;330:1029-35. PubMed
- Heinonen OP, Albanes D, Virtamo J, et al. Prostate cancer and supplementation with alpha-tocopherol and beta-carotene: incidence and mortality in a controlled trial. J Natl Cancer Inst 1998;90:440-6.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
- Pryor WA, Stahl W, Rock CL. Beta carotene: from biochemistry to clinical trials. Nutr Rev 2000;58:39-53. PubMed
- Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-93. DOI
- Virtamo J, Pietinen P, Huttunen JK, et al. Incidence of cancer and mortality following alpha-tocopherol and beta-carotene supplementation: a postintervention follow-up. JAMA 2003;290:476-85..
- Cheung MC, Zhao XQ, Chait A, et al. Antioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL. Arterioscler Thromb Vasc Biol 2001;21:1320-6. PubMed
- Food Standards Agency. Medicines and Healthcare products Regulatory Agency (MHRA). Expert Group on Vitamins and Minerals. Available at: http://cot.food.gov.uk/sites/default/files/vitmin2003.pdf.
- Bjelakovic G, Nikolova D, Gluud LL, et al. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA 2007;297:842-57. PubMed
- Lawson KA, Wright ME, Subar A, et al. Multivitamin use and risk of prostate cancer in the National Institutes of Health-AARP Diet and Health Study. J Natl Cancer Inst 2007;99:754-64. PubMed
- Hemila, H., Virtamo, J., Albanes, D., and Kaprio, J. Physical activity and the common cold in men administered vitamin E and beta-carotene. Med.Sci.Sports Exerc. 2003;35(11):1815-1820.
- Hemilä H. The effect of ß-carotene on the mortality of male smokers is modified by smoking and by vitamins C and E: evidence against a uniform effect of nutrient. J Nutr Sci. 2020;9:e11. PubMed
- US Preventive Services Task Force, Mangione CM, Barry MJ, et al. Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement. JAMA 2022;327(23):2326-2333. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Rosuvastatin Is Linked to Lower Levels of One Nutrient
Natural Medicines records Rosuvastatin as a medicine that can lower these. This is not an interaction with Beta-carotene — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Rosuvastatin nutrient depletion report ›
Beta-carotene is itself a nutrient we track — see which medications may deplete BETA-CAROTENE.
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Beta-carotene and Rosuvastatin Together: Common Questions
Is it safe to take Beta-carotene with Rosuvastatin?
Are Beta-carotene and Rosuvastatin used for the same thing?
How was the Beta-carotene and Rosuvastatin combination checked?
Does Beta-carotene interact with any other medications?
Does Rosuvastatin interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.