Herb & supplement monograph

White Lily Drug Interactions, Uses, Effectiveness, Safety & More

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Reviewed by licensed pharmacists Sourced from Natural Medicines
Interaction report

Drugs that interact with White Lily

0 medications have a known interaction with White Lily, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for White Lily. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact White Lily combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

White Lily: Uses, Safety & Side Effects

The bottom line

White Lily (Lilium candidum) is a flowering plant used mostly in traditional skin care, where its bulb- or flower-infused oils are applied for minor skin problems and soothing. Good-quality human studies are very limited, so most of its reputation comes from folk use rather than strong science. Talk with a pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have sensitive skin.

Scientific name
Lilium candidum
Family
Liliaceae
Part used
Bulbs and flowers (sometimes prepared as oil or ointment)
Common forms
Topical oils, ointments, infused oil, creams, and traditional poultices
People commonly use it for
  • Skin soothing and minor wounds
  • Burns and skin irritation
  • Cosmetic and anti-aging skin care
  • Corns and calluses (traditional)
  • Inflamed or chapped skin

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Mostly used topically with limited safety data; skin reactions are possible.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

White Lily, known botanically as Lilium candidum, is a tall perennial herb with fragrant white flowers. It is native to the Mediterranean, Balkan, and Middle Eastern regions and has been grown for centuries as an ornamental and a folk remedy.

In traditional medicine, the bulbs and flowers are often soaked in oil to make a soothing preparation that people apply to the skin. It also appears in some cosmetic creams and oils. Today it is found mainly in topical products rather than as a pill or tea.

How it works

White Lily bulbs and flowers contain plant compounds such as flavonoids, saponins, and other substances that laboratory studies suggest may have soothing or antioxidant effects. The oil-based preparations may also act as a simple emollient, helping soften and moisturize the skin.

It is important to note that these proposed mechanisms come mostly from laboratory or animal research, not from well-designed human trials. The exact way it might help skin in people is not clearly established.

Effectiveness

Does White Lily work?

Evidence overview · 6 uses evaluated
6 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For White Lily, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 6 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Back pain
Rating & evidence shown verbatim from Natural Medicines

It is unclear if topical white lily is beneficial in patients with back pain.

Insufficient Reliable Evidence To Rate Bleeding
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral white lily for bleeding, there is insufficient reliable information about the clinical effects of white lily for this condition.

Insufficient Reliable Evidence To Rate Burns
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using topical white lily for burns, there is insufficient reliable information about the clinical effects of white lily for this condition.

Insufficient Reliable Evidence To Rate Cough
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral white lily for cough, there is insufficient reliable information about the clinical effects of white lily for this condition.

Insufficient Reliable Evidence To Rate Pressure ulcers
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using topical white lily for pressure ulcers, there is insufficient reliable information about the clinical effects of white lily for this condition.

Insufficient Reliable Evidence To Rate Wound healing
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using topical white lily for wound healing, there is insufficient reliable information about the clinical effects of white lily for this condition.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

White Lily is mainly used on the skin, and there is little reliable safety information about taking it by mouth. Because of this, swallowing the plant or its preparations is not recommended. Some lily species can be toxic if eaten, so it should not be used as food or a tea unless directed by a qualified professional.

People with sensitive skin or plant allergies should do a small patch test first and stop if irritation occurs. Pregnant and breastfeeding women should avoid White Lily because there is not enough information to consider it safe. Keep lily plants and products away from children and pets, since some lilies are poisonous, especially to cats.

Side effects

When applied to the skin, the most likely side effects are mild irritation, redness, or an allergic skin reaction (contact dermatitis) in sensitive people. Stop using it if you notice a rash, itching, or swelling.

Serious side effects are not well documented because the plant has not been carefully studied in people. Eating any part of the plant could cause stomach upset or other harmful effects and should be avoided.

Dosing

There is no established standardized dose for White Lily. It is sold mostly as topical oils, creams, and ointments, and amounts vary widely between products.

If you use a commercial product, follow the directions on the label and apply only to the skin unless a professional tells you otherwise. Because reliable dosing information is missing, it is a good idea to check with a pharmacist or doctor before using it.

Pregnancy & Breastfeeding

White Lily & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using.

White Lily & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 2 sources that drive our White Lily monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing.

  1. Poisonous Plants — MedlinePlus (U.S. National Library of Medicine) Source
  2. Using Dietary Supplements Wisely — NIH National Center for Complementary and Integrative Health (NCCIH) Source
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Product directory

Supplement products with White Lily

45 products in our database contain White Lily. Open any to see its full ingredient list and every drug interaction we check.

Bladder Formula by Christopher's Original Formulas Capsule 100 Vegetarian Cap(s) View ingredients & interactions Can-Sol by Pure Herbs Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Can-Sol by Pure Herbs Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions Can-Sol by Pure Herbs Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Can-Sol by Pure Herbs Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions Cell-Ease by Earth Friend Herb Co. Liquid 1 Fluid Ounce · 30 Milliliter(s) View ingredients & interactions Cell-Ease by Earth Friend Herb Co. Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions David Winston's Replenish Compound by Herbalist & Alchemist Liquid 2 fl. Oz. · 60 mL View ingredients & interactions Fibro-Ease by Earth Friend Herb Co. Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Fibro-Ease LG by Earth Friend Herb Co. Liquid 1 Fluid Ounce · 30 Milliliter(s) View ingredients & interactions FP-W by Pure Herbs Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions FP-W by Pure Herbs Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Immunagen by Earth Friend Herb Co. Liquid 1 Fluid Ounce · 30 mL View ingredients & interactions Immunagen by Earth Friend Herb Co. Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Kid-e-Dry by Dr. Christopher's Original Formulas Liquid 2 fl. Oz. View ingredients & interactions Kidney-Bladder Ease by Earth Friend Herb Co. Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Kidney-Bladder Ease by Earth Friend Herb Co. Liquid 1 Fluid Ounce · 30 Milliliter(s) View ingredients & interactions Maletone by Earth Friend Herb Co. Liquid 1 Fluid Ounce · 30 mL View ingredients & interactions Maletone by Earth Friend Herb Co. Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Memory-Ease by Earth Friend Herb Co. Liquid 1 Fluid Ounce · 30 mL View ingredients & interactions Memory-Ease by Earth Friend Herb Co. Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Neural-Ease by Earth Friend Herb Co. Liquid 1 Fluid Ounce · 30 Milliliter(s) View ingredients & interactions Neural-Ease by Earth Friend Herb Co. Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Organilax by Earth Friend Herb Co. Liquid 1 Fluid Ounce · 30 Milliliter(s) View ingredients & interactions
Pharmacist Counseling Corner

White Lily: Common Questions

What is White Lily used for, and does it work?
People use White Lily for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does White Lily interact with prescription medications?
We do not currently list any known drug interactions for White Lily. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are White Lily interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take White Lily with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this White Lily interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is White Lily used for?
It is used mostly in traditional skin care to soothe minor burns, irritated or chapped skin, and corns, and it appears in some cosmetic products. These are traditional uses, not proven medical treatments.
Is White Lily safe to take by mouth?
No. White Lily is meant for topical use, and there is little safety data for swallowing it. Some lily plants are toxic if eaten, so do not use it internally unless a qualified professional directs you.
Can I use White Lily during pregnancy or breastfeeding?
It is best to avoid it. There is not enough reliable information to know it is safe during pregnancy or breastfeeding.
Can White Lily cause an allergic reaction?
Yes, like many plant products it can cause skin irritation or an allergic reaction in sensitive people. Do a small patch test first and stop using it if a rash develops.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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