Beta-hydroxybutyrate (bhb) - Oxbryta (Voxelotor) Interaction
Herbal: Beta-hydroxybutyrate (bhb)
Also Known As: 3-Hydroxybutanoic acid
Drug: Voxelotor
Brand names:
Oxbryta
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 04, 2025
Interaction Details
There were no interactions found between Voxelotor and Beta-hydroxybutyrate (bhb). This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Beta-hydroxybutyrate (bhb) Overview
Beta-hydroxybutyrate (BHB) is a type of ketone body produced by the liver during periods of low food intake or carbohydrate restriction. It is used as an alternative energy source by the body, especially the brain, when glucose levels are low. BHB also plays significant roles in cellular signaling, inflammation reduction, and gene expression. Additionally, it's commercially available as a dietary supplement for weight loss and athletic performance enhancement.
Voxelotor Overview
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Voxelotor is used to treat sickle cell disease (an inherited blood disease) in adults and children 4 years of age and older. Voxelotor is in a class of medications called hemoglobin S (HbS) polymerization inhibitors. It works by helping hemoglobin (a protein in red blood cells) to hold onto more oxygen and to stop red blood cells from becoming misshapen.
Beta-hydroxybutyrate (bhb) - More Interactions
Beta-hydroxybutyrate (bhb) interacts with 0 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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