Drug & supplement interaction

Bitter Yam + Dihydroxyaluminum Sodium Carbonate

Dihydroxyaluminum Sodium Carbonate brand name: Rolaids.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Bitter Yam and Dihydroxyaluminum Sodium Carbonate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Bitter Yam and Dihydroxyaluminum Sodium Carbonate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Dihydroxyaluminum Sodium Carbonate and Bitter Yam in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Bitter Yam safety at a glance

Bitter Yam overall Use caution Human safety data are limited, and improperly prepared bitter yam can be toxic.
Pregnancy Avoid Not enough safety information exists, so it is best avoided during pregnancy.
Breastfeeding Avoid There is no reliable safety data, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Dihydroxyaluminum Sodium Carbonate and Bitter Yam? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Dihydroxyaluminum Sodium Carbonate

Interactions in our licensed database are recorded against drug classes, not just single drug names. Dihydroxyaluminum Sodium Carbonate is filed under 3 classifications — aluminum, antacids, oral drugs. Bitter Yam has documented interactions with 1 drug class — the most serious being digoxin (lanoxin) (moderate) — and none of Dihydroxyaluminum Sodium Carbonate’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Bitter Yam Does Interact With Other Medications

Bitter Yam has 1 moderate known drug interaction in our database — Dihydroxyaluminum Sodium Carbonate isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Bitter Yam

Covers the 2,830 medications we’ve checked against Bitter Yam. Pick one to open its full report.

Overlapping uses

What Dihydroxyaluminum Sodium Carbonate Is Prescribed For, and What Bitter Yam Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Dihydroxyaluminum Sodium Carbonate is a prescription medicine with approved uses on its FDA label. Bitter Yam is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Dihydroxyaluminum Sodium Carbonate is prescribed for: Most calcium carbonate products here are antacids. They relieve heartburn, acid indigestion, sour stomach and upset stomach linked to those symptoms. A few supplement products have different uses. Na Mi Cal is intended to support bone development and maintenance in adolescents and adults, and may help prevent osteoporosis.

Read the rest of what Dihydroxyaluminum Sodium Carbonate is prescribed for

Ki No Sin is a health supplement used to help with body functions affected by diabetes and kidney disease, and to help maintain normal calcium ion levels. R Cos is a dietary supplement meant to support the immune system.

Bitter Yam has been studied for:

  • Diabetes studied, not established Bitter Yam has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Bitter Yam for diabetes

    Although there has been interest in using oral bitter yam for diabetes, there is insufficient reliable information about the clinical effects of bitter yam for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Dihydroxyaluminum Sodium Carbonate on your own; if you are taking Bitter Yam for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Bitter Yam or Dihydroxyaluminum Sodium Carbonate

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Bitter Yam or Dihydroxyaluminum Sodium Carbonate, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Dihydroxyaluminum Sodium Carbonate

This page covers Bitter Yam only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Dihydroxyaluminum Sodium Carbonate page lists 35 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Calcium (moderate), Cinchona (moderate), Coffee Charcoal (moderate) and European Mandrake (moderate).

By severity: 1 major · 14 moderate · 20 minor.

From our pharmacist’s overview on the Dihydroxyaluminum Sodium Carbonate page

“Rolaids (dihydroxyaluminum sodium carbonate) sits in plenty of medicine cabinets, yet its interaction list earns genuine caution rather than a shrug. Of 35 supplement and herbal ingredients on file, the lone major rating belongs to activated charcoal, which adsorbs many medications and can strip away their effect.”

Reviewed by 2 · Jul 18, 2026

Open the Dihydroxyaluminum Sodium Carbonate interaction page

How much people look this up

Where Bitter Yam and Dihydroxyaluminum Sodium Carbonate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Bitter Yam
Steady interest

#883 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Dihydroxyaluminum Sodium Carbonate
Top 10%

#167 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Bitter Yam reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Bitter Yam and Dihydroxyaluminum Sodium Carbonate records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Bitter Yam

What is Bitter Yam?

Bitter Yam
  • Blood sugar support
  • Digestive complaints
  • Traditional food source
  • Wound and skin care (folk use)

Bitter yam is a wild African yam used traditionally as both food and folk medicine, often for blood sugar and digestion. Scientific evidence in humans is very limited, and some bitter yam species can be toxic if not properly prepared. Talk to a pharmacist or doctor before using it as a supplement.

Dioscorea dumetorum · Dioscoreaceae · Tuber (root) · Cooked tuber, dried powder, traditional preparations

An interaction check asks whether these two react with each other — it does not ask whether Bitter Yam is a good idea for someone in your situation. Here is what our Bitter Yam record says about it on its own.

Bitter Yam: dosing

There is no established, standardized dose of bitter yam as a supplement. Traditional use varies widely and depends on how the tuber is prepared.If you choose to use a commercial product, follow the directions on the label and do not take more than recommended.

From our Bitter Yam monograph — the full record covers uses, side effects and every documented interaction.

Read the full Bitter Yam monograph & all interactions
Medication

About Calcium Carbonate

What Is Calcium Carbonate Used For?

Brand name: Rolaids

Most calcium carbonate products here are antacids. They relieve heartburn, acid indigestion, sour stomach and upset stomach linked to those symptoms.

A few supplement products have different uses. Na Mi Cal is intended to support bone development and maintenance in adolescents and adults, and may help prevent osteoporosis. Ki No Sin is a health supplement used to help with body functions affected by diabetes and kidney disease, and to help maintain normal calcium ion levels. R Cos is a dietary supplement meant to support the immune system.

See full Calcium Carbonate drug information
Keep checking

Other Drugs & Bitter Yam

Browse every other medication we’ve checked against Bitter Yam — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
1Moderate
0Minor
2,828No known interaction
Moderate

1 interaction

No interaction 2,828 drugs checked — show the list
Evidence & sources

Bitter Yam References

The 1 references that drive our Bitter Yam monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Nimenibo-Uadia R. Control of hyperlipidaemia, hypercholesterolaemia and hyperketonaemia by aqueous extract of Dioscorea dumetorum tuber. Trop J Pharm Res 2003;2:183-9. Available at: http://www.bioline.org.br/request?pr03009. DOI

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Bitter Yam and Dihydroxyaluminum Sodium Carbonate Together: Common Questions

Is it safe to take Bitter Yam with Dihydroxyaluminum Sodium Carbonate?
We do not list a known interaction between Bitter Yam and Dihydroxyaluminum Sodium Carbonate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Bitter Yam and Dihydroxyaluminum Sodium Carbonate used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Bitter Yam in each. That is a conversation for your prescriber, especially if Dihydroxyaluminum Sodium Carbonate is being adjusted to a target.
How was the Bitter Yam and Dihydroxyaluminum Sodium Carbonate combination checked?
Interactions in our licensed database are recorded against drug classes. Dihydroxyaluminum Sodium Carbonate is filed under 3 classifications, and Bitter Yam has documented interactions with 1 drug class — none of Dihydroxyaluminum Sodium Carbonate's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Bitter Yam interact with any other medications?
Yes. Bitter Yam has 1 documented drug interaction in our database — Dihydroxyaluminum Sodium Carbonate is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Dihydroxyaluminum Sodium Carbonate interact with any supplements?
Yes. Dihydroxyaluminum Sodium Carbonate has documented interactions with 35 supplements in our database — Bitter Yam is not one of them. The Dihydroxyaluminum Sodium Carbonate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Dihydroxyaluminum Sodium Carbonate and Bitter Yam?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.