Drug & supplement interaction

Blackberry + Sacubitril, Valsartan

Sacubitril, Valsartan brand name: Entresto.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 27, 2026
The bottom line No known interaction

We found no known interaction between Blackberry and Sacubitril, Valsartan in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Blackberry and Sacubitril, Valsartan

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Sacubitril, Valsartan and Blackberry in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Blackberry at all — not against Sacubitril, Valsartan, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Blackberry safety at a glance

Blackberry overall Generally safe The fruit is safe as a food; medicinal leaf and root preparations are likely safe in typical amounts but less studied.
Pregnancy Use caution The berry as food is fine, but concentrated leaf or root supplements lack safety data, so use caution.
Breastfeeding Use caution Eating the fruit is fine, but there is not enough information on medicinal supplements while nursing.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Sacubitril, Valsartan and Blackberry? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Sacubitril, Valsartan’s Own FDA Label Lists

This is not an interaction — none of it involves Blackberry. These are the most notable effects listed in the ADVERSE REACTIONS section of Sacubitril, Valsartan’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 5 of them are worth acting on rather than waiting out — marked below.

  • High potassium Worth acting on
  • Heart failure Worth acting on
  • Kidney problems Worth acting on
  • A severe allergic reaction Worth acting on
  • An allergic reaction Worth acting on
  • Cough
  • Low blood pressure
  • Itching
  • Dizziness
  • A skin rash

From the ADVERSE REACTIONS section of the FDA label for Sacubitril, Valsartan. Read the label on DailyMed › Blackberry’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Blackberry side to compare — that is a limit of the record, not a statement that Blackberry has no side effects.

Everything else you take

See Every Supplement That Interacts With Sacubitril, Valsartan

This page covers Blackberry only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Sacubitril, Valsartan page lists 249 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Lithium (major) and Oleander (major).

By severity: 7 major · 206 moderate · 36 minor.

From our pharmacist’s overview on the Sacubitril, Valsartan page

“Entresto (sacubitril and valsartan) is a heart failure medicine, and heart failure patients tend to be heavy supplement users, reaching for fish oil, potassium, and herbal blood-pressure remedies. That instinct carries real risk here.”

Reviewed by 2 · Jul 18, 2026

Open the Sacubitril, Valsartan interaction page

One more smart check

Taking Blackberry as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1,648 real supplement products containing Blackberry, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Blackberry. Even though Blackberry itself has no known interaction with Sacubitril, Valsartan, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Blackberry and Sacubitril, Valsartan Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Blackberry
Top 25%

#204 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Sacubitril, Valsartan
Top 5%

#140 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Blackberry is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Blackberry reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Blackberry and Sacubitril, Valsartan records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Blackberry

What is Blackberry?

  • Diarrhea
  • Sore throat and mouth rinse
  • General antioxidant support
  • Digestive upset
  • Source of vitamins and fiber

Blackberry is a common edible berry that is safe and nutritious as a food, rich in vitamin C, fiber, and antioxidant plant compounds. The leaves and root have a long history of traditional use for diarrhea and sore throat, but high-quality human studies on these medicinal uses are limited. Enjoy the fruit freely, but talk to your pharmacist or doctor before using concentrated leaf or root supplements.

Rubus fruticosus · Rosaceae · Fruit, leaves, and root · Fresh or frozen fruit, juice, tea (from dried leaves), capsules, extracts

An interaction check asks whether these two react with each other — it does not ask whether Blackberry is a good idea for someone in your situation. Here is what our Blackberry record says about it on its own.

Blackberry: dosing

There is no official standardized dose for blackberry as a supplement. As a food, blackberries can be eaten freely as part of a balanced diet.For leaf teas or extracts, traditional use varies and a reliable evidence-based dose has not been established. If you choose to use a blackberry supplement, follow the directions on the product label and do not exceed the recommended amount.

From our Blackberry monograph — the full record covers uses, side effects and every documented interaction.

Read the full Blackberry monograph & all interactions
Medication

About Valsartan and Sacubitril

What Is Valsartan and Sacubitril Used For?

Brand name: Entresto

Sacubitril and valsartan is used to reduce the risk of cardiovascular death and hospitalization for heart failure in adult patients with chronic heart failure. The benefit is most clearly seen in patients whose heart pumps with a lower-than-normal ejection fraction (the percentage of blood the heart pushes out with each beat).

It is also approved to treat symptomatic heart failure with reduced left ventricular function in children aged 1 year and older. In pediatric patients, it lowers a blood marker of heart stress (NT-proBNP) and is expected to improve heart outcomes.

See full Valsartan and Sacubitril drug information
Keep checking

Other Drugs & Blackberry

Browse every other medication we’ve checked against Blackberry — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Blackberry against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Blackberry list.

See the full Blackberry interactions page
See every supplement checked against Sacubitril, Valsartan, ranked by severity
Evidence & sources

Blackberry References

The 1 sources that drive our Blackberry monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Blackberry is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Antioxidants: In Depth — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Blackberry and Sacubitril, Valsartan Together: Common Questions

Is it safe to take Blackberry with Sacubitril, Valsartan?
We do not list a known interaction between Blackberry and Sacubitril, Valsartan. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Sacubitril, Valsartan interact with any supplements?
Yes. Sacubitril, Valsartan has documented interactions with 249 supplements in our database — Blackberry is not one of them. The Sacubitril, Valsartan interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Blackberry monograph Uses, safety profile, and every drug interaction in one place Valsartan and Sacubitril drug information The full plain-English guide to this medication Sacubitril, Valsartan supplement interactions Every supplement checked against Sacubitril, Valsartan, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Sacubitril, Valsartan and Blackberry?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.