Drug & supplement interaction

Blueberry + Pegfilgrastim

Pegfilgrastim brand name: Neulasta.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Blueberry and Pegfilgrastim in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Blueberry and Pegfilgrastim

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Pegfilgrastim and Blueberry in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Blueberry safety at a glance

Blueberry overall Generally safe Blueberries are widely eaten as food and are generally safe for most people.
Pregnancy Likely Safe When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of blueberry for medicinal use; avoid... Read the full pregnancy detail
Breastfeeding Likely Safe When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of blueberry for medicinal use; avoid... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Pegfilgrastim and Blueberry? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
Keep it in perspective

Blueberry Does Interact With Other Medications

Blueberry has 88 minor known drug interactions in our database — Pegfilgrastim isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Blueberry

Covers the 2,830 medications we’ve checked against Blueberry. Pick one to open its full report.

What to actually watch for

What Blueberry Itself Has Been Linked To

This is not an interaction — nothing below involves Pegfilgrastim. It is the side-effect record for Blueberry on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Blueberry, this list is the first place to look.

  • Constipation / Diarrhea / Vomiting / Nausea Additional detail

    “Orally, freeze-dried blueberries may cause constipation, diarrhea, nausea, and vomiting. In one clinical trial, 26% of patients taking freeze-dried blueberries 50 grams daily dropped out in the first week of the study due to gastrointestinal complaints.”

    Blueberry · Natural Medicines adverse-effect record, reported in constipation.

    1 source cited
    1. 107278. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Blueberry — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Pegfilgrastim’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Pegfilgrastim column appears here.

Special populations

Blueberry in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of blueberry for medicinal use; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Pegfilgrastim Is Prescribed For, and What Blueberry Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Pegfilgrastim is a prescription medicine with approved uses on its FDA label. Blueberry is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Pegfilgrastim is prescribed for: Pegfilgrastim injection is used in adults and children (from newborns and older) with non-myeloid cancers (cancers that do not start in blood-forming cells) who are receiving myelosuppressive chemotherapy — drugs that can severely lower white blood cell counts. It works to lower the risk of febrile neutropenia (a dangerous drop in infection-fighting white blood cells that causes fever), which can lead to serious infections. It is also used to improve survival in people who have been acutely exposed to myelosuppressive doses of radiation — doses high enough to damage the bone marrow. Pegfilgrastim is not approved to mobilize stem cells for bone marrow transplantation.

Blueberry has been studied for:

  • Cancer studied, not established Blueberry has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Blueberry for cancer

    Although there has been interest in using oral blueberry for preventing cancer, there is insufficient reliable information about the clinical effects of blueberry for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Pegfilgrastim on your own; if you are taking Blueberry for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

One more smart check

Taking Blueberry as Part of a Dietary Supplement Product? Check It for Interactions

We hold 5,076 real supplement products containing Blueberry, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Blueberry. Even though Blueberry itself has no known interaction with Pegfilgrastim, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Blueberry and Pegfilgrastim Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Blueberry
Top 5%

#53 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Pegfilgrastim
Steady interest

#2,449 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Blueberry reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Blueberry and Pegfilgrastim records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Blueberry

What is Blueberry?

  • Antioxidant support
  • Heart health
  • Brain and memory health
  • Blood sugar support
  • Eye health
  • Urinary health

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most people. Concentrated supplements are marketed for heart, brain, and blood sugar health, but the evidence is mostly early and not strong enough to promise specific benefits. Enjoy blueberries as food, and talk to your pharmacist before using high-dose extracts.

Vaccinium spp. · Ericaceae · Fruit (berries); sometimes leaves · Fresh or frozen fruit, juice, dried berries, powder, extract capsules, tea

An interaction check asks whether these two react with each other — it does not ask whether Blueberry is a good idea for someone in your situation. Here is what our Blueberry record says about it on its own.

Blueberry: dosing

There is no official standardized dose of blueberry for any health condition. As a food, a typical serving is around a half to one cup of fresh berries, which most people can enjoy daily.For supplements such as extract capsules, powders, or juices, the right amount varies by product, and a proven medical dose has not been established.

From our Blueberry monograph — the full record covers uses, side effects and every documented interaction.

Read the full Blueberry monograph & all interactions
Medication

About Pegfilgrastim Injection

What Is Pegfilgrastim Injection Used For?

Brand name: Neulasta

Pegfilgrastim injection is used in adults and children (from newborns and older) with non-myeloid cancers (cancers that do not start in blood-forming cells) who are receiving myelosuppressive chemotherapy — drugs that can severely lower white blood cell counts. It works to lower the risk of febrile neutropenia (a dangerous drop in infection-fighting white blood cells that causes fever), which can lead to serious infections.

It is also used to improve survival in people who have been acutely exposed to myelosuppressive doses of radiation — doses high enough to damage the bone marrow. Pegfilgrastim is not approved to mobilize stem cells for bone marrow transplantation.

Most-Reported Side Effects for Pegfilgrastim

From FAERS, the FDA’s public side-effect reporting system (100,585 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Device adhesion issue 11,741 reports
Unintentional medical device removal 8,992 reports
Device malfunction 7,729 reports
Device use error 6,059 reports
Device issue 5,181 reports
See full Pegfilgrastim Injection drug information
Keep checking

Other Drugs & Blueberry

Browse every other medication we’ve checked against Blueberry — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
88Minor
2,741No known interaction
Minor

88 interactions

Showing 60 of 88 minor interactions — see all 88 on the Blueberry page.

No interaction 2,741 drugs checked — show the list
Evidence & sources

Blueberry References

The 7 references that drive our Blueberry monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
  4. Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
  5. Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
  6. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
  7. Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Blueberry and Pegfilgrastim Together: Common Questions

Is it safe to take Blueberry with Pegfilgrastim?
We do not list a known interaction between Blueberry and Pegfilgrastim. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Blueberry and Pegfilgrastim used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Blueberry in each. That is a conversation for your prescriber, especially if Pegfilgrastim is being adjusted to a target.
Does Blueberry interact with any other medications?
Yes. Blueberry has 88 documented drug interactions in our database — Pegfilgrastim is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Pegfilgrastim and Blueberry?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.