Buckhorn Plantain + Denileukin
Denileukin brand name: Ontak.
We found no known interaction between Buckhorn Plantain and Denileukin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Buckhorn Plantain and Denileukin
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Denileukin and Buckhorn Plantain in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Buckhorn Plantain at all — not against Denileukin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Buckhorn Plantain safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Buckhorn Plantain in Pregnancy & Breastfeeding
When used orally or topically. Some evidence suggests buckhorn plantain affects muscle tone of the uterus.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
See Every Supplement That Interacts With Denileukin
This page covers Buckhorn Plantain only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Denileukin page lists 17 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).
By severity: 1 major · 7 moderate · 9 minor.
From our pharmacist’s overview on the Denileukin page
“Activated charcoal is the interaction I would settle first for anyone receiving denileukin (Ontak), a cancer treatment for cutaneous T-cell lymphoma. It carries the only major rating among the 17 supplements on file, and unlike the rest it can lower drug exposure no matter how the medicine is given, because it traps compounds that reci…”
Reviewed by 2 · Jul 18, 2026
Taking Buckhorn Plantain as Part of a Dietary Supplement Product? Check It for Interactions
We hold 4 real supplement products containing Buckhorn Plantain, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Buckhorn Plantain. Even though Buckhorn Plantain itself has no known interaction with Denileukin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Buckhorn Plantain and Denileukin Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,421 of 1,452 supplements looked up here in the last 7 days
#2,653 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Buckhorn Plantain reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Buckhorn Plantain and Denileukin records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Buckhorn Plantain
What is Buckhorn Plantain?
- Cough and sore throat
- Respiratory irritation
- Wound and skin care
- Digestive upset
- Mild inflammation
Buckhorn plantain is a common weed-like herb used traditionally for coughs, sore throats, and minor skin wounds. Some lab and small studies suggest it has soothing and mild anti-inflammatory effects, but high-quality human evidence is limited. It is generally considered low-risk for short-term use, but pregnant and breastfeeding people should be cautious and check with a healthcare provider.
Plantago lanceolata · Plantaginaceae · Leaves (above-ground parts) · Tea, tincture, syrup, capsules, topical creams or ointments, fresh crushed leaves
An interaction check asks whether these two react with each other — it does not ask whether Buckhorn Plantain is a good idea for someone in your situation. Here is what our Buckhorn Plantain record says about it on its own.
Buckhorn Plantain: dosing
There is no official standardized dose for buckhorn plantain. Traditional preparations include teas made from the dried leaves, syrups, tinctures, and topical products.Because product strength varies a lot between brands and forms, the best approach is to follow the directions on the product label.
From our Buckhorn Plantain monograph — the full record covers uses, side effects and every documented interaction.
About Denileukin Diftitox Injection
What Is Denileukin Diftitox Injection Used For?
Brand name: Ontak
LYMPHIR is approved for adults with cutaneous T-cell lymphoma (CTCL) — a cancer that starts in certain white blood cells and mainly affects the skin — specifically Stage I through III disease that has relapsed (come back) or is refractory (no longer responding) after at least one prior systemic (whole-body) treatment.
It is not a first-line therapy. It's used when earlier treatments have already been tried and the cancer has continued to progress.
Other Drugs & Buckhorn Plantain
Browse every other medication we’ve checked against Buckhorn Plantain — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Buckhorn Plantain against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Warfarin ›
- Methylphenidate ›
- Sertraline ›
- Losartan Potassium ›
- Testosterone ›
- Ivermectin ›
- Metoprolol ›
- Rivaroxaban ›
- Aspirin ›
- Acetaminophen ›
- Rosuvastatin ›
- Abemaciclib ›
- Escitalopram ›
- Clopidogrel ›
- Tadalafil ›
- Atorvastatin ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Hydroxyurea ›
- Valacyclovir ›
- Methamphetamine ›
- Warfarin Sodium ›
- Semaglutide ›
- Sumatriptan ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Amitriptyline ›
- Bupropion ›
- Methotrexate ›
- Bendamustine ›
- Isotretinoin ›
- Amphetamine ›
- Acyclovir ›
- Doxycycline ›
- Amlodipine Besylate ›
- Fluoxetine ›
- Lamotrigine ›
- Pregabalin ›
- Azithromycin ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Dextroamphetamine ›
- Quetiapine ›
- Clonazepam ›
- Methylene Blue ›
- Omeprazole ›
- Letrozole ›
- Naproxen ›
- Duloxetine ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Buckhorn Plantain list.
Buckhorn Plantain References
The 1 references that drive our Buckhorn Plantain monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Shipochliev T. Uterotonic action of extracts from a group of medicinal plants. Vet Med Nauki 1981;18:94-8.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Buckhorn Plantain and Denileukin Together: Common Questions
Is it safe to take Buckhorn Plantain with Denileukin?
Does Denileukin interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Denileukin and Buckhorn Plantain?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.