Caffeic Acid + Enfortumab Vedotin-Ejfv
Enfortumab Vedotin-Ejfv brand name: Padcev.
We found no known interaction between Caffeic Acid and Enfortumab Vedotin-Ejfv in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Caffeic Acid and Enfortumab Vedotin-Ejfv
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Enfortumab Vedotin-Ejfv and Caffeic Acid in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Caffeic Acid safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Enfortumab Vedotin-Ejfv
Interactions in our licensed database are recorded against drug classes, not just single drug names. Enfortumab Vedotin-Ejfv is filed under a single classification — cytochrome p450 3a4 (cyp3a4) substrates. Caffeic Acid has documented interactions with 3 drug classes — the most serious being organic anion transporter 1 (oat1) substrates (moderate), organic anion transporter 3 (oat3) substrates (moderate) and levodopa (minor) — and none of Enfortumab Vedotin-Ejfv’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Caffeic Acid Does Interact With Other Medications
Caffeic Acid has 177 moderate, 5 minor known drug interactions in our database — Enfortumab Vedotin-Ejfv isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Caffeic Acid
We haven’t checked that one against Caffeic Acid yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Caffeic Acid. Pick one to open its full report.
See Every Supplement That Interacts With Enfortumab Vedotin-Ejfv
This page covers Caffeic Acid only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Enfortumab Vedotin-Ejfv page lists 121 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate), Adrafinil (moderate) and African Wild Potato (moderate).
By severity: 2 major · 87 moderate · 32 minor.
From our pharmacist’s overview on the Enfortumab Vedotin-Ejfv page
“If you are getting Padcev (enfortumab vedotin) infusions for bladder cancer, treat this page as one worth genuine attention. The chemotherapy payload in Padcev is cleared by a liver enzyme called CYP3A4, and all 121 ingredients listed here act on that enzyme, either blocking it so the drug builds up or speeding it up so treatment weakens.”
Reviewed by 2 · Jul 18, 2026
Taking Caffeic Acid as Part of a Dietary Supplement Product? Check It for Interactions
We hold 20 real supplement products containing Caffeic Acid, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Caffeic Acid. Even though Caffeic Acid itself has no known interaction with Enfortumab Vedotin-Ejfv, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Caffeic Acid and Enfortumab Vedotin-Ejfv Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,269 of 1,452 supplements looked up here in the last 7 days
#417 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Caffeic Acid reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Caffeic Acid and Enfortumab Vedotin-Ejfv records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Caffeic Acid
What is Caffeic Acid?
- Antioxidant support
- General anti-inflammatory use
- Skin and sun protection (topical)
- Immune support
- Cancer-prevention interest (research stage)
Caffeic acid is a natural plant compound found in coffee, many fruits, vegetables, and herbs, and it is studied mainly for its antioxidant and anti-inflammatory properties. Most evidence comes from laboratory and animal research, so its benefits in people are not yet proven. If you want to take it as a supplement, talk with your pharmacist or doctor first.
Naturally occurring plant compound (found in coffee, fruits, and many herbs) · Capsules, tablets, powders, and as part of plant extracts (such as coffee or propolis)
An interaction check asks whether these two react with each other — it does not ask whether Caffeic Acid is a good idea for someone in your situation. Here is what our Caffeic Acid record says about it on its own.
Caffeic Acid: dosing
There is no established standard dose of caffeic acid as a supplement. Research studies have used different amounts, and a safe, effective dose for general use has not been confirmed.If you choose to use a product that contains caffeic acid, follow the directions on the label and do not exceed the recommended amount.
From our Caffeic Acid monograph — the full record covers uses, side effects and every documented interaction.
About Enfortumab vedotin-ejfv Injection
What Is Enfortumab vedotin-ejfv Injection Used For?
Brand name: Padcev
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Enfortumab vedotin-ejfv injection is used to treat urothelial cancer (cancer of the lining of the bladder and other parts of the urinary tract) that has spread to nearby tissues or other parts of the body or cannot be removed by surgery, and has worsened after treatment with other chemotherapy medications or if these chemotherapy medications cannot be used for treatment. Enfortumab vedotin-ejfv injection is in a class of medications called monoclonal antibodies. It works by helping your immune system to slow or stop the growth of cancer cells.
Other Drugs & Caffeic Acid
Browse every other medication we’ve checked against Caffeic Acid — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
177 interactions
- Diclofenac Sodium ›
- Ibuprofen ›
- Aspirin ›
- Naproxen ›
- Ranitidine ›
- Hydrochlorothiazide ›
- Ciprofloxacin ›
- Flurbiprofen ›
- Ceftazidime ›
- Diclofenac Potassium ›
- Indomethacin ›
- Salsalate ›
- Acyclovir ›
- Cephalexin ›
- Etodolac ›
- Famotidine ›
- Ketoprofen ›
- Meloxicam ›
- Methotrexate ›
- Cefadroxil ›
- Cefuroxime ›
- Cimetidine ›
- Probenecid ›
- Sulindac ›
- Tolmetin Sodium ›
- Cefaclor ›
- Celecoxib ›
- Cephradine ›
- Diclofenac Epolamine ›
- Ketorolac Tromethamine ›
- Nabumetone ›
- Nepafenac ›
- Pemetrexed ›
- Phenylbutazone ›
- Piroxicam ›
- Tenoxicam ›
- Tiaprofenic Acid ›
- Zidovudine ›
- Acetylsalicylic Acid ›
- Adefovir ›
- Baricitinib ›
- Bempedoic Acid ›
- Cefamandole ›
- Cefazolin ›
- Cefdinir ›
- Cefditoren Pivoxil ›
- Cefepime ›
- Cefixime ›
- Cefmetazole ›
- Cefonicid ›
- Cefoperazone ›
- Cefotaxime ›
- Cefotetan ›
- Cefoxitin ›
- Cefpodoxime Proxetil ›
- Cefprozil ›
- Ceftibuten ›
- Ceftizoxime ›
- Ceftriaxone ›
- Cephalothin ›
Showing 60 of 177 moderate interactions — see all 177 on the Caffeic Acid page.
5 interactions
No interaction 2,647 drugs checked — show the list
We also checked Caffeic Acid against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Acetaminophen ›
- Tadalafil ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Sumatriptan ›
- Semaglutide ›
- Tirzepatide ›
- Warfarin Sodium ›
- Prednisone ›
- Propranolol ›
- Bupropion ›
- Lisdexamfetamine ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Fluoxetine ›
- Lamotrigine ›
- Amphetamine ›
- Gabapentin ›
- Pregabalin ›
- Acetaminophen, Codeine ›
- Azithromycin ›
- Dextroamphetamine ›
- Isotretinoin ›
- Clonazepam ›
- Omeprazole ›
- Quetiapine ›
- Methylene Blue ›
- Amlodipine Besylate ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Bisoprolol ›
- Levothyroxine, Liothyronine ›
- Acetaminophen, Oxycodone ›
- Dapsone ›
- Diazepam ›
- Cyclopentolate ›
- Candesartan Cilexetil ›
Showing the 60 most looked-up of 2,647 medications checked with no known interaction — see the full Caffeic Acid list.
Caffeic Acid References
The 2 references that drive our Caffeic Acid monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Uwai Y, Ozeki Y, Isaka T, et al. Inhibitory effect of caffeic acid on human organic anion transporters hOAT1 and hOAT3: a novel candidate for food-drug interaction. Drug Metab Pharmacokinet 2011;26:486-93. PubMed
- Wang LH, Hsu KY, Uang YS, et al. Caffeic acid improves the bioavailability of L-dopa in rabbit plasma. Phytother Res 2010;24:852-8.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Caffeic Acid and Enfortumab Vedotin-Ejfv Together: Common Questions
Is it safe to take Caffeic Acid with Enfortumab Vedotin-Ejfv?
How was the Caffeic Acid and Enfortumab Vedotin-Ejfv combination checked?
Does Caffeic Acid interact with any other medications?
Does Enfortumab Vedotin-Ejfv interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.