Carbon 60 (c60) + Colesevelam
Colesevelam brand names: WelChol, Lodalis.
We found no known interaction between Carbon 60 (c60) and Colesevelam in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Colesevelam states a food rule worth keeping to.
Carbon 60 (c60) and Colesevelam
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Colesevelam and Carbon 60 (c60) in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Carbon 60 (c60) at all — not against Colesevelam, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Carbon 60 (c60) safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Some Colesevelam Products Have a Food Rule — Carbon 60 (c60) Should Not Break It
At least one FDA label for a product containing Colesevelam says to take it with food. If you take Carbon 60 (c60) on an empty stomach out of habit, keep them separate — and take Colesevelam with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Colesevelam products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
Colesevelam hydrochloride should be taken as follows ( 2.2 , 2.4 ): Tablets Take 6 tablets once daily or 3 tablets twice daily with a meal and liquid.
From the Dosage and Administration section of the FDA label we read for Colesevelam — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
Questions About Carbon 60 (c60) or Colesevelam
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Carbon 60 (c60) or Colesevelam, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Colesevelam
This page covers Carbon 60 (c60) only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Colesevelam page lists 17 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).
By severity: 1 major · 7 moderate · 9 minor.
From our pharmacist’s overview on the Colesevelam page
“Colesevelam (WelChol, Lodalis) lowers cholesterol by binding bile acids in your gut, and every one of the 17 supplements on this list can interfere with how oral medicines are absorbed in that same territory. I would treat this list with genuine care, and the place to start is activated charcoal, the only major-rated entry.”
Reviewed by 2 · Jul 18, 2026
Where Carbon 60 (c60) and Colesevelam Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,255 of 1,452 supplements looked up here in the last 7 days
#1,717 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Carbon 60 (c60) is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Carbon 60 (c60) reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Carbon 60 (c60) and Colesevelam records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Carbon 60 (c60)
What is Carbon 60 (c60)?
- Antioxidant support
- Anti-aging and longevity
- Energy and vitality
- Athletic recovery
- General wellness
Carbon 60 (C60) is a man-made molecule made of 60 carbon atoms, usually sold dissolved in oil and marketed as a powerful antioxidant or anti-aging supplement. Despite bold marketing, there is no good human evidence that it provides any of these benefits, and its long-term safety in people is unknown. Talk to your pharmacist or doctor before trying it, and avoid it during pregnancy and breastfeeding.
Not applicable (synthetic carbon molecule) · Liquid (C60 dissolved in oils such as olive, coconut, or avocado oil), softgels, capsules
An interaction check asks whether these two react with each other — it does not ask whether Carbon 60 (c60) is a good idea for someone in your situation. Here is what our Carbon 60 (c60) record says about it on its own.
Carbon 60 (c60): dosing
There is no established or standardized dose for C60. Because there are no reliable human studies, no one can say what amount is safe or effective.If you choose to use a C60 product, follow the directions on the label and do not exceed them. It is a good idea to choose products from companies that provide third-party testing for purity.
From our Carbon 60 (c60) monograph — the full record covers uses, side effects and every documented interaction.
About Colesevelam
What Is Colesevelam Used For?
Brand names: WelChol, Lodalis
Colesevelam is used alongside diet and exercise to reduce high LDL cholesterol (the "bad" cholesterol) in adults with primary hyperlipidemia (high cholesterol). It is also approved to lower LDL cholesterol in boys and girls aged 10–17 who have heterozygous familial hypercholesterolemia (HeFH) — an inherited condition that causes very high cholesterol — when diet and lifestyle changes alone haven't worked.
Colesevelam tablets and oral suspension (Welchol and colesevelam hydrochloride products) are also used to improve blood sugar control in adults with type 2 diabetes, as an add-on to diet and exercise. Colesevelam is not for type 1 diabetes or diabetic ketoacidosis.
Most-Reported Side Effects for Colesevelam
From FAERS, the FDA’s public side-effect reporting system (2,014 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Carbon 60 (c60)
Browse every other medication we’ve checked against Carbon 60 (c60) — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Carbon 60 (c60) against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Warfarin ›
- Methylphenidate ›
- Sertraline ›
- Testosterone ›
- Ivermectin ›
- Losartan Potassium ›
- Aspirin ›
- Abemaciclib ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Tadalafil ›
- Tirzepatide ›
- Methamphetamine ›
- Ibuprofen ›
- Warfarin Sodium ›
- Valacyclovir ›
- Hydroxyurea ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Amitriptyline ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Amlodipine Besylate ›
- Methotrexate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Doxycycline ›
- Fluoxetine ›
- Azithromycin ›
- Acyclovir ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Levothyroxine, Liothyronine ›
- Clonazepam ›
- Quetiapine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Duloxetine ›
- Methylene Blue ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Carbon 60 (c60) list.
Carbon 60 (c60) References
The 3 sources that drive our Carbon 60 (c60) monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Carbon 60 (c60) is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.
- Antioxidants: In Depth — NIH NCCIH Source
- Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
- Dietary Supplements — MedlinePlus Source
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Carbon 60 (c60) and Colesevelam Together: Common Questions
Is it safe to take Carbon 60 (c60) with Colesevelam?
Should I take Carbon 60 (c60) and Colesevelam at the same time of day?
Does Colesevelam interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.