Drug & supplement interaction

Cardarine + Rasagiline

Rasagiline brand name: Azilect.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Cardarine and Rasagiline in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Cardarine and Rasagiline

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Rasagiline and Cardarine in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Cardarine at all — not against Rasagiline, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Cardarine safety at a glance

Cardarine overall Avoid Animal studies linked it to cancer and it is not approved or proven safe for human use.
Pregnancy Possibly Unsafe When used orally or parenterally. Some metabolic modulators have been found to cause cancer in animals. Their safety in humans has not been tested. Avoid using. Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally or parenterally. Some metabolic modulators have been found to cause cancer in animals. Their safety in humans has not been tested. Avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Rasagiline and Cardarine? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Rasagiline’s Own FDA Label Lists

This is not an interaction — none of it involves Cardarine. These are the most notable effects listed in the ADVERSE REACTIONS section of Rasagiline’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 9 of them are worth acting on rather than waiting out — marked below.

  • Serotonin syndrome Worth acting on
  • Unsteadiness Worth acting on
  • Hallucinations Worth acting on
  • Confusion Worth acting on
  • Low mood Worth acting on
  • Raised blood pressure Worth acting on
  • Shortness of breath Worth acting on
  • Bleeding or bruising Worth acting on
  • A higher chance of infection Worth acting on
  • Vivid dreams or nightmares

Showing the 10 most notable of 34 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Rasagiline. Read the label on DailyMed › Cardarine’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Cardarine side to compare — that is a limit of the record, not a statement that Cardarine has no side effects.

Special populations

Cardarine in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally or parenterally. Some metabolic modulators have been found to cause cancer in animals. Their safety in humans has not been tested. Avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Rasagiline

This page covers Cardarine only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Rasagiline page lists 173 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Bitter Orange (major), Brewer's Yeast (major) and Cowhage (major).

By severity: 14 major · 125 moderate · 34 minor.

From our pharmacist’s overview on the Rasagiline page

“Rasagiline (Azilect) treats Parkinson's disease by blocking monoamine oxidase, the same enzyme that clears tyramine from aged and fermented foods. That shared pathway explains most of the 14 major-rated interactions on this page.”

Reviewed by 2 · Jul 18, 2026

Open the Rasagiline interaction page

One more smart check

Taking Cardarine as Part of a Dietary Supplement Product? Check It for Interactions

We hold 18 real supplement products containing Cardarine, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Cardarine. Even though Cardarine itself has no known interaction with Rasagiline, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Cardarine and Rasagiline Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Cardarine
Steady interest

#1,126 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Rasagiline
Top half

#1,301 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Cardarine reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Cardarine and Rasagiline records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Cardarine

What is Cardarine?

  • Endurance and athletic performance
  • Fat loss and body recomposition
  • Bodybuilding cycles
  • Increasing exercise capacity

Cardarine (GW501516) is a synthetic experimental drug, not a vitamin, herb, or true dietary supplement, even though it is often sold as one. Animal studies linked it to a higher risk of cancer, drug development was halted, and it is banned in sports — so it should not be used. There is no proven safe dose for humans.

Not applicable (synthetic chemical compound) · Capsules, tablets, oral liquids, powders (sold as a 'research chemical')

An interaction check asks whether these two react with each other — it does not ask whether Cardarine is a good idea for someone in your situation. Here is what our Cardarine record says about it on its own.

Cardarine: dosing

There is no established safe or approved dose of Cardarine for humans. It is not approved by the FDA for any condition, and no medical or pharmacy authority endorses a dosing plan.Doses listed on websites and forums are not based on reliable safety research and should not be trusted.

From our Cardarine monograph — the full record covers uses, side effects and every documented interaction.

Read the full Cardarine monograph & all interactions
Medication

About Rasagiline

What Is Rasagiline Used For?

Brand name: Azilect

Rasagiline tablets — sold as Azilect, Rasagiline, and Rasagiline mesylate — are approved to treat Parkinson's disease. They can be used on their own (monotherapy) or alongside other Parkinson's medications, including levodopa.

When used with levodopa, rasagiline helps smooth out the motor fluctuations that can occur as Parkinson's disease progresses. Your prescriber will determine whether it's right for you as a standalone treatment or as an add-on.

Most-Reported Side Effects for Rasagiline

From FAERS, the FDA’s public side-effect reporting system (11,069 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fall 1,066 reports
Hallucination 960 reports
Dyskinesia 765 reports
Dizziness 659 reports
Tremor 650 reports
See full Rasagiline drug information
Keep checking

Other Drugs & Cardarine

Browse every other medication we’ve checked against Cardarine — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Cardarine References

The 1 references that drive our Cardarine monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. What Should Tested Athletes Know About GW1516? Education, Spirit of Sport. U.S. Anti-Doping Agency (USADA). September 24, 2019. Available at: https://www.usada.org/spirit-of-sport/education/what-should-athletes-know-gw1516/

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Cardarine and Rasagiline Together: Common Questions

Is it safe to take Cardarine with Rasagiline?
We do not list a known interaction between Cardarine and Rasagiline. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Rasagiline interact with any supplements?
Yes. Rasagiline has documented interactions with 173 supplements in our database — Cardarine is not one of them. The Rasagiline interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Rasagiline and Cardarine?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.