Drug & supplement interaction

Carlina + Ferric Citrate

Ferric Citrate brand name: Auryxia.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Carlina and Ferric Citrate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Ferric Citrate states a food rule worth keeping to.

Know someone taking this? Share
Interaction report

Carlina and Ferric Citrate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ferric Citrate and Carlina in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Carlina at all — not against Ferric Citrate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Carlina safety at a glance

Carlina overall Use caution Human safety data are limited, so use carefully and only under guidance.
Pregnancy Avoid Not enough safety information; avoid use during pregnancy.
Breastfeeding Avoid No reliable safety data; avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ferric Citrate and Carlina? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Ferric Citrate’s Own FDA Label Lists

This is not an interaction — none of it involves Carlina. These are the most notable effects listed in the ADVERSE REACTIONS section of Ferric Citrate’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 3 of them are worth acting on rather than waiting out — marked below.

  • High potassium Worth acting on
  • Kidney problems Worth acting on
  • Anemia Worth acting on
  • Cough
  • Constipation
  • Stomach pain
  • Diarrhea
  • Vomiting
  • Nausea

From the ADVERSE REACTIONS section of the FDA label for Ferric Citrate. Read the label on DailyMed › Carlina’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Carlina side to compare — that is a limit of the record, not a statement that Carlina has no side effects.

How to take them

Some Ferric Citrate Products Have a Food Rule — Carlina Should Not Break It

At least one FDA label for a product containing Ferric Citrate says to take it with food. If you take Carlina on an empty stomach out of habit, keep them separate — and take Ferric Citrate with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Ferric Citrate products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

( 2.2 ) 2.1 Dosage for Hyperphosphatemia in Chronic Kidney Disease on Dialysis The recommended starting dose is 2 tablets, swallowed whole, 3 times per day with meals.

From the Dosage and Administration section of the FDA label we read for Ferric Citrate — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Ferric Citrate

This page covers Carlina only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ferric Citrate page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Ferric Citrate page

“Ferric citrate (Auryxia) does its work in the gut, binding dietary phosphate in kidney disease or supplying iron, and all 17 supplements on this list can interfere with how oral medicines get absorbed. That is worth real caution, starting with the single major-rated entry, activated charcoal, which adsorbs many drugs directly and can m…”

Reviewed by 2 · Jul 18, 2026

Open the Ferric Citrate interaction page

One more smart check

Taking Carlina as Part of a Dietary Supplement Product? Check It for Interactions

We hold 38 real supplement products containing Carlina, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Carlina. Even though Carlina itself has no known interaction with Ferric Citrate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Carlina and Ferric Citrate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Carlina
Steady interest

#933 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ferric Citrate
Steady interest

#1,436 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Carlina is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Carlina reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Carlina and Ferric Citrate records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Carlina

What is Carlina?

Carlina
  • Digestive upset and poor appetite
  • Diuretic (increasing urine flow)
  • Skin conditions when used topically
  • Antimicrobial folk remedy
  • Mild laxative or 'detox' use

Carlina (Carlina acaulis) is a thistle-like plant whose root has long been used in European folk medicine for digestive and skin complaints. Modern scientific evidence in humans is very limited, so its benefits are largely unproven. Because safety data are sparse, talk with a pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Carlina acaulis · Asteraceae · Root, and sometimes the flower heads and aerial parts · Dried root, tea/decoction, tincture, and traditional herbal preparations

An interaction check asks whether these two react with each other — it does not ask whether Carlina is a good idea for someone in your situation. Here is what our Carlina record says about it on its own.

Carlina: dosing

There is no well-established or standardized dose for Carlina. Traditional preparations were often made as a root tea or tincture, but the right amount, strength, and safe length of use have not been defined by good research.If you choose to use a product, follow the directions on the label and do not exceed them.

From our Carlina monograph — the full record covers uses, side effects and every documented interaction.

Read the full Carlina monograph & all interactions
Medication

About Ferric Citrate

What Is Ferric Citrate Used For?

Brand name: Auryxia

Ferric citrate tablets — sold as Auryxia and under the generic name Ferric Citrate — are approved for two related uses in adults with chronic kidney disease (CKD).

For patients on dialysis, they work as a phosphate binder to control high phosphorus (hyperphosphatemia) levels in the blood. For patients with CKD who are not on dialysis, they serve as an iron replacement to treat iron deficiency anemia.

Most-Reported Side Effects for Ferric Citrate

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Diarrhea 307 reports
Serum ferritin increased 228 reports
Transferrin saturation increased 169 reports
Faeces discoloured 118 reports
Constipation 83 reports
See full Ferric Citrate drug information
Keep checking

Other Drugs & Carlina

Browse every other medication we’ve checked against Carlina — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Carlina References

The 2 sources that drive our Carlina monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Carlina is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  2. Herbs at a Glance — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Carlina and Ferric Citrate Together: Common Questions

Is it safe to take Carlina with Ferric Citrate?
We do not list a known interaction between Carlina and Ferric Citrate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Carlina and Ferric Citrate at the same time of day?
At least one FDA label for a product containing Ferric Citrate says to take it with food. If you take Carlina on an empty stomach out of habit, keep them separate and take Ferric Citrate with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Ferric Citrate products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Ferric Citrate interact with any supplements?
Yes. Ferric Citrate has documented interactions with 17 supplements in our database — Carlina is not one of them. The Ferric Citrate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Ferric Citrate and Carlina?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.