Drug & supplement interaction

Chaulmoogra + Maralixibat

Maralixibat brand name: Livmarli.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Chaulmoogra and Maralixibat in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Chaulmoogra and Maralixibat

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Maralixibat and Chaulmoogra in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Chaulmoogra at all — not against Maralixibat, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Chaulmoogra safety at a glance

Chaulmoogra overall Use caution Largely outdated remedy with limited modern safety data and a history of irritation and side effects.
Pregnancy Avoid Not enough safety information; avoid during pregnancy.
Breastfeeding Avoid Not enough safety information; avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Maralixibat and Chaulmoogra? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Chaulmoogra Itself Has Been Linked To

This is not an interaction — nothing below involves Maralixibat. It is the side-effect record for Chaulmoogra on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Chaulmoogra, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Kidney problems / Shortness of breath Worth acting on Additional detail

    “Orally, ingestion of the seed can cause cough, dyspnea, laryngospasms, nephrotoxicity, visual disorders, head and muscle pain, and central paralysis (18).

    Topically, use can cause skin irritation (18).”

    Chaulmoogra · Natural Medicines adverse-effect record, reported in cough.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  • Cough / Muscle pain Additional detail

    Recorded for Chaulmoogra in the same Natural Medicines adverse-effect record shown under Kidney problems / Shortness of breath above.

Everything above comes from the Natural Medicines adverse-effect record for Chaulmoogra — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Maralixibat’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Maralixibat column appears here.

Everything else you take

See Every Supplement That Interacts With Maralixibat

This page covers Chaulmoogra only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Maralixibat page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Maralixibat page

“Maralixibat (Livmarli) relieves the severe itching caused by rare childhood liver diseases like Alagille syndrome, and since it does its job inside the intestine, this list warrants genuine vigilance, not a shrug. All 17 supplement entries share one mechanism, ingredients that trap or slow drugs in the gut and change how much of a dose…”

Reviewed by 2 · Jul 18, 2026

Open the Maralixibat interaction page

How much people look this up

Where Chaulmoogra and Maralixibat Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Chaulmoogra
Steady interest

#1,103 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Maralixibat
Steady interest

#1,928 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Chaulmoogra reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Chaulmoogra and Maralixibat records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Chaulmoogra

What is Chaulmoogra?

  • Leprosy (historical)
  • Skin conditions and rashes
  • Wound and sore care
  • Eczema and psoriasis (traditional)
  • Rheumatic complaints (traditional)

Chaulmoogra oil is an old herbal remedy famous for being the main treatment for leprosy before modern antibiotics. Today it has been replaced by safer, more effective drugs, and there is little reliable modern evidence to support its use. If you are considering it, talk to a pharmacist or doctor first, and avoid it during pregnancy and breastfeeding.

Hydnocarpus kurzii · Achariaceae · Seed oil (chaulmoogra oil) and seeds · Seed oil, topical preparations, and historically injectable oil derivatives

An interaction check asks whether these two react with each other — it does not ask whether Chaulmoogra is a good idea for someone in your situation. Here is what our Chaulmoogra record says about it on its own.

Chaulmoogra: dosing

There is no established, standardized dose for chaulmoogra in modern use, and it is not a recommended treatment today. Historical doses varied widely and were used under medical supervision in an era before modern drugs.If you find a product that contains chaulmoogra, follow the directions on the label and do not use it internally.

From our Chaulmoogra monograph — the full record covers uses, side effects and every documented interaction.

Read the full Chaulmoogra monograph & all interactions
Medication

About Maralixibat

What Is Maralixibat Used For?

Brand name: Livmarli

Livmarli (maralixibat) is used to treat cholestatic pruritus (intense itching caused by bile acid buildup in the body) in two rare liver conditions. It is approved for patients aged 3 months and older with Alagille syndrome (ALGS), and for patients aged 12 months and older with progressive familial intrahepatic cholestasis (PFIC).

There is an important limitation for PFIC: Livmarli is not recommended for a specific subgroup of PFIC type 2 patients who have certain gene variants (ABCB11 variants) that result in a non-functional or completely absent bile salt export pump (BSEP) protein.

See full Maralixibat drug information
Keep checking

Other Drugs & Chaulmoogra

Browse every other medication we’ve checked against Chaulmoogra — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Chaulmoogra against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Chaulmoogra list.

See the full Chaulmoogra interactions page
See every supplement checked against Maralixibat, ranked by severity
Evidence & sources

Chaulmoogra References

The 1 references that drive our Chaulmoogra monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Chaulmoogra and Maralixibat Together: Common Questions

Is it safe to take Chaulmoogra with Maralixibat?
We do not list a known interaction between Chaulmoogra and Maralixibat. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Maralixibat interact with any supplements?
Yes. Maralixibat has documented interactions with 17 supplements in our database — Chaulmoogra is not one of them. The Maralixibat interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Chaulmoogra monograph Uses, safety profile, and every drug interaction in one place Maralixibat drug information The full plain-English guide to this medication Maralixibat supplement interactions Every supplement checked against Maralixibat, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Maralixibat and Chaulmoogra?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.