Drug & supplement interaction

Chia + Treprostinil (IV)

Treprostinil (IV) brand name: Remodulin.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Chia and Treprostinil (IV) in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Chia and Treprostinil (IV)

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Treprostinil (IV) and Chia in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Chia at all — not against Treprostinil (IV), and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Chia safety at a glance

Chia overall Generally safe Chia is widely eaten as food and is generally well tolerated in normal amounts.
Pregnancy Use caution Likely fine as a food, but there is little research on concentrated supplement amounts, so stick to food portions and ask your doctor.
Breastfeeding Use caution Food amounts are likely fine, but high supplement doses have not been well studied, so use caution.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Treprostinil (IV) and Chia? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Chia and Treprostinil (IV) May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Shortness of breath Worth acting on Additional detail

    Chia

    “Orally, chia might cause anaphylaxis in sensitive individuals. A single case of IgE-mediated anaphylactic reaction has been reported for a patient who consumed chia seeds. Symptoms, including pruritus in the mouth, urticaria, facial angioedema, shortness of breath, and dizziness, developed a few days after consuming chia seeds. The reaction was attributed to sensitivity to proteins in chia seeds.”

    Chia · Natural Medicines adverse-effect record, reported in vertigo.

    1 source cited
    1. 91517. García Jiménez S, Pastor Vargas C, de las Heras M, Sanz Maroto A, Vivanco F, Sastre J. Allergen characterization of chia seeds (Salvia hispanica), a new allergenic food. J Investig Allergol Clin Immunol. 2015;25(1):55-6.

    Treprostinil (IV)

    Listed in the ADVERSE REACTIONS section of the FDA label for Treprostinil (IV). Read the label on DailyMed ›

  • Itching / Dizziness Additional detail

    Chia

    Recorded for Chia in the same Natural Medicines adverse-effect record shown under Shortness of breath above.

    Treprostinil (IV)

    Listed in the ADVERSE REACTIONS section of the FDA label for Treprostinil (IV). Read the label on DailyMed ›

  • Diarrhea Additional detail

    Chia

    “Orally, chia might cause mild gastrointestinal adverse effects. Some patients consuming chia 40 grams daily for up to 6 months reported mild and transient gastrointestinal adverse effects such as flatulence and soft stools; however, the frequency of these adverse effects was similar to patients consuming an oat bran control. Bloating and flatulence have been reported with a chia flour-based sports beverage.”

    Chia · Natural Medicines adverse-effect record, reported in flatulence.

    2 sources cited
    1. 97940. Vuksan V, Jenkins AL, Brissette C, et al. Salba-chia (Salvia hispanica L.) in the treatment of overweight and obese patients with type 2 diabetes: a double-blind randomized controlled trial. Nutr Metab Cardiovasc Dis 2017;27(2):138-46. PubMed
    2. 112385. Zbinden-Foncea H, Ramos-Navarro C, Hevia-Larraín V, et al. Neither Chia Flour nor Whey Protein Supplementation Further Improves Body Composition or Strength Gains after a Resistance Training Program in Young Subjects with a Habitual High Daily Protein Int

    Treprostinil (IV)

    Listed in the ADVERSE REACTIONS section of the FDA label for Treprostinil (IV). Read the label on DailyMed ›

Reported for Chia but not commonly for Treprostinil (IV): a severe allergic reaction, bloating or gas and hives.

Effects for Treprostinil (IV) come from the ADVERSE REACTIONS section of its FDA label; effects for Chia come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Overlapping uses

What Treprostinil (IV) Is Prescribed For, and What Chia Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Treprostinil (IV) is a prescription medicine with approved uses on its FDA label. Chia is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Treprostinil (IV) is prescribed for: Treprostinil injection is used to treat pulmonary arterial hypertension (PAH, WHO Group 1) — high blood pressure in the arteries that supply the lungs. It works to reduce the symptoms that make exercise difficult. Clinical studies included patients with moderate-to-severe PAH symptoms (NYHA Class II–IV) due to idiopathic or heritable PAH, PAH related to congenital heart defects, and PAH related to connective tissue diseases. It is also used for PAH patients who need to transition off epoprostenol — a related medication — to slow the worsening of their condition during that switch.

Read the rest of what Treprostinil (IV) is prescribed for

The risks and benefits of the transition should be carefully discussed with a specialist before starting.

Chia has been studied for:

  • Hypertension studied, not established Chia has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Chia for hypertension

    It is unclear if oral chia is beneficial in patients with hypertension.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Treprostinil (IV) on your own; if you are taking Chia for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Treprostinil (IV)

This page covers Chia only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Treprostinil (IV) page lists 212 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: American Mistletoe (major), Danshen (major), Piracetam (major), Aconite (moderate) and African Wild Potato (moderate).

By severity: 3 major · 191 moderate · 18 minor.

From our pharmacist’s overview on the Treprostinil (IV) page

“Bleeding risk is the thread running through nearly every supplement flagged for treprostinil (Remodulin), the IV therapy for pulmonary arterial hypertension. The drug itself discourages platelets from clumping, so the overwhelming majority of these ingredients could push that tendency further, and I would not add anything from this pag…”

Reviewed by 2 · Jul 18, 2026

Open the Treprostinil (IV) interaction page

One more smart check

Taking Chia as Part of a Dietary Supplement Product? Check It for Interactions

We hold 638 real supplement products containing Chia, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Chia. Even though Chia itself has no known interaction with Treprostinil (IV), another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Chia and Treprostinil (IV) Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Chia
Top half

#404 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Treprostinil (IV)
Top half

#824 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Chia reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Chia and Treprostinil (IV) records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Chia

What is Chia?

  • Source of fiber and omega-3 fats
  • Digestive health and regularity
  • Heart health and cholesterol
  • Blood sugar support
  • Weight management

Chia seeds are a nutritious whole food rich in fiber, plant-based omega-3 fats (ALA), and protein. They are generally safe as part of a healthy diet, and may modestly help with regularity and fullness, but strong proof for treating specific health conditions is limited. Drink plenty of water with them and start with small amounts.

Salvia hispanica · Lamiaceae · Seeds · Whole seeds, ground seeds, chia gel, oil, capsules, flour, fortified foods

An interaction check asks whether these two react with each other — it does not ask whether Chia is a good idea for someone in your situation. Here is what our Chia record says about it on its own.

Chia: dosing

There is no official, standardized medicinal dose for chia. It is usually eaten as a food, often a tablespoon or two per day added to meals, but amounts vary from person to person.If you use a chia product or supplement, follow the directions on the label and increase your intake gradually. Always take chia with a generous amount of water or other liquid.

From our Chia monograph — the full record covers uses, side effects and every documented interaction.

Read the full Chia monograph & all interactions
Medication

About Treprostinil Injection

What Is Treprostinil Injection Used For?

Brand name: Remodulin

Treprostinil injection is used to treat pulmonary arterial hypertension (PAH, WHO Group 1) — high blood pressure in the arteries that supply the lungs. It works to reduce the symptoms that make exercise difficult. Clinical studies included patients with moderate-to-severe PAH symptoms (NYHA Class II–IV) due to idiopathic or heritable PAH, PAH related to congenital heart defects, and PAH related to connective tissue diseases.

It is also used for PAH patients who need to transition off epoprostenol — a related medication — to slow the worsening of their condition during that switch. The risks and benefits of the transition should be carefully discussed with a specialist before starting.

See full Treprostinil Injection drug information
Keep checking

Other Drugs & Chia

Browse every other medication we’ve checked against Chia — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Chia against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Chia list.

See the full Chia interactions page
See every supplement checked against Treprostinil (IV), ranked by severity
Evidence & sources

Chia References

The 12 references that drive our Chia monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Kolonel LN, Nomura AM, Cooney RV. Dietary fat and prostate cancer: current status. J Natl Cancer Inst 1999;91:414-28. PubMed
  2. Ramon JM, Bou R, Romea S, et al. Dietary fat intake and prostate cancer risk: a case-control study in Spain. Cancer Causes Control 2000;11:679-85. PubMed
  3. De Stefani E, Deneo-Pellegrini H, Boffetta P, et al. Alpha-linolenic acid and risk of prostate cancer: a case-control study in Uruguay. Cancer Epidemiol Biomarkers Prev 2000;9:335-8.
  4. Giovannucci E, Rimm EB, Colditz GA, et al. A prospective study of dietary fat and risk of prostate cancer. J Natl Cancer Inst 1993;85:1571-9. PubMed
  5. Laaksonen DE, Laukkanen JA, Niskanen L, et al. Serum linoleic and total polyunsaturated fatty acids in relation to prostate and other cancers: a population-based cohort study. Int J Cancer 2004;111:444-50.. PubMed
  6. Leitzmann MF, Stampfer MJ, Michaud DS, et al. Dietary intake of n-3 and n-6 fatty acids and the risk of prostate cancer. Am J Clin Nutr 2004;80:204-16. PubMed
  7. Brouwer IA, Katan MB, Zock PL. Dietary alpha-linolenic acid is associated with reduced risk of fatal coronary heart disease, but increased prostate cancer risk: a meta-analysis. J Nutr 2004;134:919-22.
  8. Chavarro JE, Stampfer MJ, Li H, et al. A prospective study of polyunsaturated fatty acid levels in blood and prostate cancer risk. Cancer Epidemiol Biomarkers Prev 2007;16:1364-70. PubMed
  9. Brouwer IA, Geleijnse JM, Klaasen VM, Smit LA, Giltay EJ, de Goede J, Heijboer AC, Kromhout D, Katan MB. Effect of alpha linolenic acid supplementation on serum prostate specific antigen (PSA): results from the alpha omega trial. PLoS One. 2013 Dec 11;8(1 PubMed
  10. García Jiménez S, Pastor Vargas C, de las Heras M, Sanz Maroto A, Vivanco F, Sastre J. Allergen characterization of chia seeds (Salvia hispanica), a new allergenic food. J Investig Allergol Clin Immunol. 2015;25(1):55-6.
  11. Vuksan V, Jenkins AL, Brissette C, et al. Salba-chia (Salvia hispanica L.) in the treatment of overweight and obese patients with type 2 diabetes: a double-blind randomized controlled trial. Nutr Metab Cardiovasc Dis 2017;27(2):138-46. PubMed
  12. Zbinden-Foncea H, Ramos-Navarro C, Hevia-Larraín V, et al. Neither Chia Flour nor Whey Protein Supplementation Further Improves Body Composition or Strength Gains after a Resistance Training Program in Young Subjects with a Habitual High Daily Protein Int

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Chia and Treprostinil (IV) Together: Common Questions

Is it safe to take Chia with Treprostinil (IV)?
We do not list a known interaction between Chia and Treprostinil (IV). That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Chia and Treprostinil (IV) have any of the same side effects?
Yes — our sources link each of them separately to 4 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Are Chia and Treprostinil (IV) used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Chia in each. That is a conversation for your prescriber, especially if Treprostinil (IV) is being adjusted to a target.
Does Treprostinil (IV) interact with any supplements?
Yes. Treprostinil (IV) has documented interactions with 212 supplements in our database — Chia is not one of them. The Treprostinil (IV) interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Chia monograph Uses, safety profile, and every drug interaction in one place Treprostinil Injection drug information The full plain-English guide to this medication Treprostinil (IV) supplement interactions Every supplement checked against Treprostinil (IV), ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 12 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Treprostinil (IV) and Chia?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.