Drug & supplement interaction

Chia + Tadalafil

Tadalafil brand names: Cialis, Tadliq.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Chia and Tadalafil in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Chia and Tadalafil

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tadalafil and Chia in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Chia at all — not against Tadalafil, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Chia safety at a glance

Chia overall Generally safe Chia is widely eaten as food and is generally well tolerated in normal amounts.
Pregnancy Use caution Likely fine as a food, but there is little research on concentrated supplement amounts, so stick to food portions and ask your doctor.
Breastfeeding Use caution Food amounts are likely fine, but high supplement doses have not been well studied, so use caution.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tadalafil and Chia? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Chia Itself Has Been Linked To

This is not an interaction — nothing below involves Tadalafil. It is the side-effect record for Chia on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Chia, this list is the first place to look. 2 entries are worth acting on rather than waiting out — marked below.

  • Shortness of breath / Hives Worth acting on Additional detail

    “Orally, chia might cause anaphylaxis in sensitive individuals. A single case of IgE-mediated anaphylactic reaction has been reported for a patient who consumed chia seeds. Symptoms, including pruritus in the mouth, urticaria, facial angioedema, shortness of breath, and dizziness, developed a few days after consuming chia seeds. The reaction was attributed to sensitivity to proteins in chia seeds.”

    Chia · Natural Medicines adverse-effect record, reported in vertigo.

    1 source cited
    1. 91517. García Jiménez S, Pastor Vargas C, de las Heras M, Sanz Maroto A, Vivanco F, Sastre J. Allergen characterization of chia seeds (Salvia hispanica), a new allergenic food. J Investig Allergol Clin Immunol. 2015;25(1):55-6.
  • A severe allergic reaction Worth acting on Additional detail

    “Orally and topically, chia seems to be well tolerated.

    Most Common Adverse Effects:

    Orally: Flatulence and soft stools.

    Serious Adverse Effects (Rare):

    Orally: Anaphylaxis in sensitive individuals.”

    Chia · Natural Medicines adverse-effect record, reported in flatulence.

  • Bloating or gas / Diarrhea Additional detail

    “Orally, chia might cause mild gastrointestinal adverse effects. Some patients consuming chia 40 grams daily for up to 6 months reported mild and transient gastrointestinal adverse effects such as flatulence and soft stools; however, the frequency of these adverse effects was similar to patients consuming an oat bran control. Bloating and flatulence have been reported with a chia flour-based sports beverage.”

    Chia · Natural Medicines adverse-effect record, reported in flatulence.

    2 sources cited
    1. 97940. Vuksan V, Jenkins AL, Brissette C, et al. Salba-chia (Salvia hispanica L.) in the treatment of overweight and obese patients with type 2 diabetes: a double-blind randomized controlled trial. Nutr Metab Cardiovasc Dis 2017;27(2):138-46. PubMed
    2. 112385. Zbinden-Foncea H, Ramos-Navarro C, Hevia-Larraín V, et al. Neither Chia Flour nor Whey Protein Supplementation Further Improves Body Composition or Strength Gains after a Resistance Training Program in Young Subjects with a Habitual High Daily Protein Int
  • Itching / Dizziness Additional detail

    Recorded for Chia in the same Natural Medicines adverse-effect record shown under Shortness of breath / Hives above.

Everything above comes from the Natural Medicines adverse-effect record for Chia — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Tadalafil’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Tadalafil column appears here.

Overlapping uses

What Tadalafil Is Prescribed For, and What Chia Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Tadalafil is a prescription medicine with approved uses on its FDA label. Chia is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Tadalafil is prescribed for: Tadalafil tablets (including Cialis and generic tadalafil) are used to treat erectile dysfunction (ED), the symptoms of benign prostatic hyperplasia (BPH — an enlarged prostate), or both conditions together. When used with the drug finasteride to start BPH treatment, this combination is recommended for up to 26 weeks. Adcirca, Alyq (tablets), and Tadliq (oral suspension) are indicated specifically for pulmonary arterial hypertension (PAH — high blood pressure in the lungs), to improve the ability to exercise.

Chia has been studied for:

  • Hypertension studied, not established Chia has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Chia for hypertension

    It is unclear if oral chia is beneficial in patients with hypertension.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Tadalafil on your own; if you are taking Chia for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Chia or Tadalafil

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Chia or Tadalafil, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Tadalafil

This page covers Chia only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tadalafil page lists 144 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Mistletoe (major), Grapefruit (major), Hawthorn (major) and St. John's Wort (major).

By severity: 5 major · 98 moderate · 41 minor.

From our pharmacist’s overview on the Tadalafil page

“Grapefruit juice is the first thing to know about if you take tadalafil (Cialis, Tadliq). It blocks CYP3A4, the enzyme that clears the drug, so blood levels climb and side effects like a steep drop in blood pressure become more likely.”

Reviewed by 2 · Jul 18, 2026

Open the Tadalafil interaction page

One more smart check

Taking Chia as Part of a Dietary Supplement Product? Check It for Interactions

We hold 638 real supplement products containing Chia, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Chia. Even though Chia itself has no known interaction with Tadalafil, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Chia and Tadalafil Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Chia
Top half

#375 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tadalafil
Top 1%

#16 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Chia reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Chia and Tadalafil records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Chia

What is Chia?

  • Source of fiber and omega-3 fats
  • Digestive health and regularity
  • Heart health and cholesterol
  • Blood sugar support
  • Weight management

Chia seeds are a nutritious whole food rich in fiber, plant-based omega-3 fats (ALA), and protein. They are generally safe as part of a healthy diet, and may modestly help with regularity and fullness, but strong proof for treating specific health conditions is limited. Drink plenty of water with them and start with small amounts.

Salvia hispanica · Lamiaceae · Seeds · Whole seeds, ground seeds, chia gel, oil, capsules, flour, fortified foods

An interaction check asks whether these two react with each other — it does not ask whether Chia is a good idea for someone in your situation. Here is what our Chia record says about it on its own.

Chia: dosing

There is no official, standardized medicinal dose for chia. It is usually eaten as a food, often a tablespoon or two per day added to meals, but amounts vary from person to person.If you use a chia product or supplement, follow the directions on the label and increase your intake gradually. Always take chia with a generous amount of water or other liquid.

From our Chia monograph — the full record covers uses, side effects and every documented interaction.

Read the full Chia monograph & all interactions
Medication

About Tadalafil

What Is Tadalafil Used For?

Brand names: Cialis, Tadliq

Tadalafil tablets (including Cialis and generic tadalafil) are used to treat erectile dysfunction (ED), the symptoms of benign prostatic hyperplasia (BPH — an enlarged prostate), or both conditions together. When used with the drug finasteride to start BPH treatment, this combination is recommended for up to 26 weeks.

Adcirca, Alyq (tablets), and Tadliq (oral suspension) are indicated specifically for pulmonary arterial hypertension (PAH — high blood pressure in the lungs), to improve the ability to exercise.

Most-Reported Side Effects for Tadalafil

From FAERS, the FDA’s public side-effect reporting system (99,210 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dyspnea 11,917 reports
Headache 10,982 reports
Diarrhea 8,020 reports
Nausea 6,697 reports
Fatigue 6,080 reports
See full Tadalafil drug information
Keep checking

Other Drugs & Chia

Browse every other medication we’ve checked against Chia — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Chia against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Chia list.

See the full Chia interactions page
See every supplement checked against Tadalafil, ranked by severity
Evidence & sources

Chia References

The 12 references that drive our Chia monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Kolonel LN, Nomura AM, Cooney RV. Dietary fat and prostate cancer: current status. J Natl Cancer Inst 1999;91:414-28. PubMed
  2. Ramon JM, Bou R, Romea S, et al. Dietary fat intake and prostate cancer risk: a case-control study in Spain. Cancer Causes Control 2000;11:679-85. PubMed
  3. De Stefani E, Deneo-Pellegrini H, Boffetta P, et al. Alpha-linolenic acid and risk of prostate cancer: a case-control study in Uruguay. Cancer Epidemiol Biomarkers Prev 2000;9:335-8.
  4. Giovannucci E, Rimm EB, Colditz GA, et al. A prospective study of dietary fat and risk of prostate cancer. J Natl Cancer Inst 1993;85:1571-9. PubMed
  5. Laaksonen DE, Laukkanen JA, Niskanen L, et al. Serum linoleic and total polyunsaturated fatty acids in relation to prostate and other cancers: a population-based cohort study. Int J Cancer 2004;111:444-50.. PubMed
  6. Leitzmann MF, Stampfer MJ, Michaud DS, et al. Dietary intake of n-3 and n-6 fatty acids and the risk of prostate cancer. Am J Clin Nutr 2004;80:204-16. PubMed
  7. Brouwer IA, Katan MB, Zock PL. Dietary alpha-linolenic acid is associated with reduced risk of fatal coronary heart disease, but increased prostate cancer risk: a meta-analysis. J Nutr 2004;134:919-22.
  8. Chavarro JE, Stampfer MJ, Li H, et al. A prospective study of polyunsaturated fatty acid levels in blood and prostate cancer risk. Cancer Epidemiol Biomarkers Prev 2007;16:1364-70. PubMed
  9. Brouwer IA, Geleijnse JM, Klaasen VM, Smit LA, Giltay EJ, de Goede J, Heijboer AC, Kromhout D, Katan MB. Effect of alpha linolenic acid supplementation on serum prostate specific antigen (PSA): results from the alpha omega trial. PLoS One. 2013 Dec 11;8(1 PubMed
  10. García Jiménez S, Pastor Vargas C, de las Heras M, Sanz Maroto A, Vivanco F, Sastre J. Allergen characterization of chia seeds (Salvia hispanica), a new allergenic food. J Investig Allergol Clin Immunol. 2015;25(1):55-6.
  11. Vuksan V, Jenkins AL, Brissette C, et al. Salba-chia (Salvia hispanica L.) in the treatment of overweight and obese patients with type 2 diabetes: a double-blind randomized controlled trial. Nutr Metab Cardiovasc Dis 2017;27(2):138-46. PubMed
  12. Zbinden-Foncea H, Ramos-Navarro C, Hevia-Larraín V, et al. Neither Chia Flour nor Whey Protein Supplementation Further Improves Body Composition or Strength Gains after a Resistance Training Program in Young Subjects with a Habitual High Daily Protein Int

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Chia and Tadalafil Together: Common Questions

Is it safe to take Chia with Tadalafil?
We do not list a known interaction between Chia and Tadalafil. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Chia and Tadalafil used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Chia in each. That is a conversation for your prescriber, especially if Tadalafil is being adjusted to a target.
Does Tadalafil interact with any supplements?
Yes. Tadalafil has documented interactions with 144 supplements in our database — Chia is not one of them. The Tadalafil interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Chia monograph Uses, safety profile, and every drug interaction in one place Tadalafil drug information The full plain-English guide to this medication Tadalafil supplement interactions Every supplement checked against Tadalafil, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 12 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Tadalafil and Chia?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.