Drug & supplement interaction

Clematis Recta + Methyclothiazide

Methyclothiazide brand names: Enduron, Aquatensen.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Clematis Recta and Methyclothiazide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Clematis Recta and Methyclothiazide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Methyclothiazide and Clematis Recta in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Clematis Recta at all — not against Methyclothiazide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Clematis Recta safety at a glance

Clematis Recta overall Use caution The raw plant is toxic and irritating; only highly diluted homeopathic forms are generally considered low-risk.
Pregnancy Likely Unsafe When the fresh plant is used orally. There is insufficient reliable information available for the safety of the dried plant; avoid using. Read the full pregnancy detail
Breastfeeding Likely Unsafe When the fresh plant is used orally. There is insufficient reliable information available for the safety of the dried plant; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Methyclothiazide and Clematis Recta? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Clematis Recta Itself Has Been Linked To

This is not an interaction — nothing below involves Methyclothiazide. It is the side-effect record for Clematis Recta on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Clematis Recta, this list is the first place to look.

  • Diarrhea Additional detail

    “Orally, fresh Clematis recta can cause colic, diarrhea, and severe irritation to the gastrointestinal tract (18).”

    Clematis Recta · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Everything above comes from the Natural Medicines adverse-effect record for Clematis Recta — expand a row for the licensed statement it rests on. We haven’t matched Methyclothiazide to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Methyclothiazide.

Special populations

Clematis Recta in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Unsafe

When the fresh plant is used orally. There is insufficient reliable information available for the safety of the dried plant; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Methyclothiazide

This page covers Clematis Recta only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Methyclothiazide page lists 227 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Asarabacca (major) and Dolomite (major).

By severity: 10 major · 192 moderate · 25 minor.

Open the Methyclothiazide interaction page

How much people look this up

Where Clematis Recta and Methyclothiazide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Clematis Recta
Steady interest

#932 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Methyclothiazide
Steady interest

#1,929 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Clematis Recta reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Clematis Recta and Methyclothiazide records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Clematis Recta

What is Clematis Recta?

  • Skin complaints and eruptions
  • Swollen or tender lymph glands
  • Urinary discomfort
  • Nerve pain
  • Men's groin and testicular discomfort (traditional homeopathic use)

Clematis recta is a flowering plant in the buttercup family that is mostly sold today as a homeopathic remedy. The fresh plant is toxic and irritating, and there is no reliable human evidence that it treats any condition, so it should be used cautiously and only under professional guidance.

Clematis recta · Ranunculaceae · Fresh leaves and stems (aerial parts), usually gathered before flowering · Homeopathic pellets, dilutions, and mother tinctures; rarely as topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Clematis Recta is a good idea for someone in your situation. Here is what our Clematis Recta record says about it on its own.

Clematis Recta: dosing

There is no established standard dose for Clematis recta. The raw plant is not recommended at all because it is toxic and irritating.When sold as a homeopathic remedy, it comes in standardized dilutions and potencies set by the manufacturer.

From our Clematis Recta monograph — the full record covers uses, side effects and every documented interaction.

Read the full Clematis Recta monograph & all interactions
Medication

About Methyclothiazide

What Is Methyclothiazide Used For?

Brand names: Enduron, Aquatensen

  • Methyclothiazide is used to treat high blood pressure. Methyclothiazide is also used to treat edema (fluid retention; excess fluid held in body tissues) caused by various medical problems, including heart, kidney, and liver disease and to treat edema caused by using certain medications including estrogen and corticosteroids. Methyclothiazide is in a class of medications called diuretics ('water pills'). It works by causing the kidneys to get rid of unneeded water and salt from the body into the urine.

  • High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

See full Methyclothiazide drug information
Keep checking

Other Drugs & Clematis Recta

Browse every other medication we’ve checked against Clematis Recta — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Clematis Recta against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Clematis Recta list.

See the full Clematis Recta interactions page
See every supplement checked against Methyclothiazide, ranked by severity
Evidence & sources

Clematis Recta References

The 1 references that drive our Clematis Recta monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Clematis Recta and Methyclothiazide Together: Common Questions

Is it safe to take Clematis Recta with Methyclothiazide?
We do not list a known interaction between Clematis Recta and Methyclothiazide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Methyclothiazide interact with any supplements?
Yes. Methyclothiazide has documented interactions with 227 supplements in our database — Clematis Recta is not one of them. The Methyclothiazide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Clematis Recta monograph Uses, safety profile, and every drug interaction in one place Methyclothiazide drug information The full plain-English guide to this medication Methyclothiazide supplement interactions Every supplement checked against Methyclothiazide, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Methyclothiazide and Clematis Recta?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.