Drug & supplement interaction

Common Stonecrop + Golodirsen

Golodirsen brand name: Vyondys 53.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 27, 2026

The bottom line No known interaction

We found no known interaction between Common Stonecrop and Golodirsen in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Common Stonecrop and Golodirsen

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Golodirsen and Common Stonecrop in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Common Stonecrop at all — not against Golodirsen, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Common Stonecrop safety at a glance

Common Stonecrop overall Use caution Limited safety data exist, and internal use can cause irritation, vomiting, and diarrhea.

Pregnancy Avoid There is not enough safety information, so avoid use during pregnancy.

Breastfeeding Avoid Safety while breastfeeding is unknown, so it is best to avoid it.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Golodirsen and Common Stonecrop? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

What to actually watch for

What Common Stonecrop Itself Has Been Linked To

This is not an interaction — nothing below involves Golodirsen. It is the side-effect record for Common Stonecrop on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Common Stonecrop, this list is the first place to look.

Diarrhea / Vomiting Additional detail
“Orally, common stonecrop can cause vomiting and diarrhea when consumed in very large amounts (18).”

Common Stonecrop · Natural Medicines adverse-effect record, reported in diarrhea.
1 source cited

18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Everything above comes from the Natural Medicines adverse-effect record for Common Stonecrop — expand a row for the licensed statement it rests on. We haven’t matched Golodirsen to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Golodirsen.

Everything else you take

See Every Supplement That Interacts With Golodirsen

This page covers Common Stonecrop only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Golodirsen page lists 6 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Asarabacca (major), Siberian Cocklebur (major), Aristolochia (moderate), Mountain Ash (moderate) and Rhubarb (moderate).

By severity: 2 major · 3 moderate · 1 minor.

From our pharmacist’s overview on the Golodirsen page

“Golodirsen (Vyondys 53) treats Duchenne muscular dystrophy in boys with a specific genetic change, and kidney injury is one of the risks doctors already watch for on this drug. Every one of the six supplements on this page is here for the same reason, added strain on the kidneys, which is why I would treat this short list with real vig…”

Reviewed by 2 · Jul 18, 2026

Open the Golodirsen interaction page

How much people look this up

Where Common Stonecrop and Golodirsen Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Common Stonecrop

Steady interest

#972 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Golodirsen

Steady interest

#2,756 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Common Stonecrop reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Common Stonecrop and Golodirsen records this page draws on were last updated July 10, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Common Stonecrop

What is Common Stonecrop?

Wounds and skin irritation
Eczema and other skin conditions
Constipation (laxative use)
Urinary and bladder complaints
High blood pressure (folk use)

Common Stonecrop (Sedum acre) is a small succulent with a long history in European folk medicine, mostly applied to the skin or used as a laxative. There is very little modern scientific evidence to support any of its uses, and the plant can be irritating and may cause vomiting or diarrhea when swallowed, so it should be used with caution and ideally avoided internally.

Sedum acre · Crassulaceae · Above-ground parts (leaves, stems, and flowering tops), used fresh or dried · Fresh plant, dried herb, topical preparations, and rarely teas or tinctures

An interaction check asks whether these two react with each other — it does not ask whether Common Stonecrop is a good idea for someone in your situation. Here is what our Common Stonecrop record says about it on its own.

Common Stonecrop: dosing

There is no established or standardized dose for Common Stonecrop. Because it has not been studied in proper clinical trials, safe and effective amounts are simply not known.If you choose to use a commercial product, follow the directions on the label and do not exceed them.

From our Common Stonecrop monograph — the full record covers uses, side effects and every documented interaction.

Read the full Common Stonecrop monograph & all interactions

Keep checking

Other Drugs & Common Stonecrop

Browse every other medication we’ve checked against Common Stonecrop — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

0Moderate

0Minor

2,829No known interaction

2,829 No interaction

No interaction 2,829 drugs checked — show the list

We also checked Common Stonecrop against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Common Stonecrop list.

See the full Common Stonecrop interactions page

See every supplement checked against Golodirsen, ranked by severity

Evidence & sources

Common Stonecrop References

The 1 references that drive our Common Stonecrop monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Common Stonecrop and Golodirsen Together: Common Questions

Is it safe to take Common Stonecrop with Golodirsen?

We do not list a known interaction between Common Stonecrop and Golodirsen. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Does Golodirsen interact with any supplements?

Yes. Golodirsen has documented interactions with 6 supplements in our database — Common Stonecrop is not one of them. The Golodirsen interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Common Stonecrop monograph Uses, safety profile, and every drug interaction in one place Golodirsen supplement interactions Every supplement checked against Golodirsen, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Golodirsen and Common Stonecrop?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.