Drug & supplement interaction

Corn Poppy + Darunavir, Cobicistat

Darunavir, Cobicistat brand name: Prezcobix.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 27, 2026

The bottom line No known interaction

We found no known interaction between Corn Poppy and Darunavir, Cobicistat in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Darunavir, Cobicistat states a food rule worth keeping to.

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Interaction report

Corn Poppy and Darunavir, Cobicistat

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Darunavir, Cobicistat and Corn Poppy in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Corn Poppy safety at a glance

Corn Poppy overall Use caution Generally low in strong alkaloids, but human safety data are limited and it should be used cautiously.

Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.

Breastfeeding Avoid Not enough safety information, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Darunavir, Cobicistat and Corn Poppy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

How we checked

Why No Interaction Is Listed for Darunavir, Cobicistat

Interactions in our licensed database are recorded against drug classes, not just single drug names. Darunavir, Cobicistat is filed under 7 classifications — including protease inhibitors (pis), cytochrome p450 1a2 (cyp1a2) inducers, cytochrome p450 2d6 (cyp2d6) inhibitors. Corn Poppy has documented interactions with 1 drug class — the most serious being cns depressants (moderate) — and none of Darunavir, Cobicistat’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Corn Poppy Does Interact With Other Medications

Corn Poppy has 248 moderate known drug interactions in our database — Darunavir, Cobicistat isn’t one of them. If you take anything else, check it against the full list below.

Moderate 248 No known interaction 2,582 (incl. Darunavir, Cobicistat)

Taking anything else?

Check Another of Your Medications Against Corn Poppy

Covers the 2,830 medications we’ve checked against Corn Poppy. Pick one to open its full report.

What to actually watch for

What Corn Poppy Itself Has Been Linked To

This is not an interaction — nothing below involves Darunavir, Cobicistat. It is the side-effect record for Corn Poppy on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Corn Poppy, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

Hives Worth acting on Additional detail
“Topically, corn poppy flowers may cause allergic contact urticaria.”

Corn Poppy · Natural Medicines adverse-effect record, reported in urticaria.
1 source cited

46284. Gamboa, P. M., Jauregui, I., Urrutia, I., Gonzalez, G., Barturen, P., and Antepara, I. Allergic contact urticaria from poppy flowers (Papaver rhoeas). Contact Dermatitis 1997;37(3):140-141.

Everything above comes from the Natural Medicines adverse-effect record for Corn Poppy — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Darunavir, Cobicistat’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Darunavir, Cobicistat column appears here.

How to take them

Some Darunavir, Cobicistat Products Have a Food Rule — Corn Poppy Should Not Break It

At least one FDA label for a product containing Darunavir, Cobicistat says to take it with food. If you take Corn Poppy on an empty stomach out of habit, keep them separate — and take Darunavir, Cobicistat with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Darunavir, Cobicistat products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

2 DOSAGE AND ADMINISTRATION Recommended dosage: Adults and pediatric patients weighing at least 40 kg: One 800 mg/150 mg tablet taken once daily with food.

From the Dosage and Administration section of the FDA label we read for Darunavir, Cobicistat — where that label names a specific product, the instruction is that product's. See the Darunavir, Cobicistat drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Darunavir, Cobicistat

This page covers Corn Poppy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Darunavir, Cobicistat page lists 145 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 102 moderate · 40 minor.

From our pharmacist’s overview on the Darunavir, Cobicistat page

“Prezcobix (darunavir with cobicistat) treats HIV, and it only works if it holds a steady blood level, so this list of 145 supplements deserves real care. Three carry a major rating and matter most: St.”

Reviewed by 2 · Jul 18, 2026

Open the Darunavir, Cobicistat interaction page

One more smart check

Taking Corn Poppy as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Corn Poppy, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Corn Poppy. Even though Corn Poppy itself has no known interaction with Darunavir, Cobicistat, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Corn Poppy and Darunavir, Cobicistat Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Corn Poppy

Steady interest

#1,023 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Darunavir, Cobicistat

Top half

#825 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Corn Poppy reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Corn Poppy and Darunavir, Cobicistat records this page draws on were last updated July 10, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Corn Poppy

What is Corn Poppy?

Cough and sore throat
Sleep and restlessness
Mild pain
Anxiety and nervousness
Digestive complaints

Corn poppy is a red-flowered plant traditionally used in teas and syrups for cough, sleep, and mild pain. Solid human research is very limited, so its benefits are not well proven, and unlike its relative the opium poppy, it contains only small amounts of weak alkaloids. Talk to a pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Papaver rhoeas · Papaveraceae · Flowers (petals) and leaves · Tea, syrup, dried petals, tincture, capsules

An interaction check asks whether these two react with each other — it does not ask whether Corn Poppy is a good idea for someone in your situation. Here is what our Corn Poppy record says about it on its own.

Corn Poppy: dosing

There is no well-established or standardized dose for corn poppy. Traditional use generally involves small amounts of the dried petals made into a tea or syrup.Because products vary widely in strength, follow the directions on the product label and do not exceed the suggested amount. Avoid giving it to infants or young children.

From our Corn Poppy monograph — the full record covers uses, side effects and every documented interaction.

Read the full Corn Poppy monograph & all interactions

Medication

About Darunavir and Cobicistat

What Is Darunavir and Cobicistat Used For?

Brand name: Prezcobix

Prezcobix and Prezcobix Ped are used to treat HIV-1 (human immunodeficiency virus type 1) infection. They are always used together with other antiretroviral (anti-HIV) medicines — never alone. Both products are approved for people who are new to HIV treatment (treatment-naïve) and for those who have taken HIV medicines before (treatment-experienced), as long as certain darunavir resistance mutations are not present.

Prezcobix tablets are approved for adults and pediatric patients weighing at least 40 kg. Prezcobix Ped tablets for oral suspension extend coverage to pediatric patients 3 years of age and older weighing at least 15 kg.

See full Darunavir and Cobicistat drug information

Keep checking

Other Drugs & Corn Poppy

Browse every other medication we’ve checked against Corn Poppy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

248Moderate

0Minor

2,581No known interaction

248 Moderate 2,581 No interaction

Moderate

248 interactions

Showing 60 of 248 moderate interactions — see all 248 on the Corn Poppy page.

No interaction 2,581 drugs checked — show the list

We also checked Corn Poppy against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,581 medications checked with no known interaction — see the full Corn Poppy list.

See the full Corn Poppy interactions page

See every supplement checked against Darunavir, Cobicistat, ranked by severity

Evidence & sources

Corn Poppy References

The 2 references that drive our Corn Poppy monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Soulimani, R., Younos, C., Jarmouni-Idrissi, S., Bousta, D., Khalouki, F., and Laila, A. Behavioral and pharmaco-toxicological study of Papaver rhoeas L. in mice. J Ethnopharmacol 3-3-2001;74(3):265-274. PubMed
Gamboa, P. M., Jauregui, I., Urrutia, I., Gonzalez, G., Barturen, P., and Antepara, I. Allergic contact urticaria from poppy flowers (Papaver rhoeas). Contact Dermatitis 1997;37(3):140-141.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Corn Poppy and Darunavir, Cobicistat Together: Common Questions

Is it safe to take Corn Poppy with Darunavir, Cobicistat?

We do not list a known interaction between Corn Poppy and Darunavir, Cobicistat. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Should I take Corn Poppy and Darunavir, Cobicistat at the same time of day?

At least one FDA label for a product containing Darunavir, Cobicistat says to take it with food. If you take Corn Poppy on an empty stomach out of habit, keep them separate and take Darunavir, Cobicistat with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Darunavir, Cobicistat products can differ — so check the directions on your own box. This is about absorption, not an interaction.

How was the Corn Poppy and Darunavir, Cobicistat combination checked?

Interactions in our licensed database are recorded against drug classes. Darunavir, Cobicistat is filed under 7 classifications, and Corn Poppy has documented interactions with 1 drug class — none of Darunavir, Cobicistat's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.

Does Corn Poppy interact with any other medications?

Yes. Corn Poppy has 248 documented drug interactions in our database — Darunavir, Cobicistat is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Does Darunavir, Cobicistat interact with any supplements?

Yes. Darunavir, Cobicistat has documented interactions with 145 supplements in our database — Corn Poppy is not one of them. The Darunavir, Cobicistat interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Corn Poppy monograph Uses, safety profile, and every drug interaction in one place Darunavir and Cobicistat drug information The full plain-English guide to this medication Darunavir, Cobicistat supplement interactions Every supplement checked against Darunavir, Cobicistat, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Darunavir, Cobicistat and Corn Poppy?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.