Drug & supplement interaction

Date Palm + Uridine Triacetate

Uridine Triacetate brand names: Xuriden, Vistogard.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Date Palm and Uridine Triacetate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Uridine Triacetate states a food rule worth keeping to.

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Interaction report

Date Palm and Uridine Triacetate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Uridine Triacetate and Date Palm in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Date Palm at all — not against Uridine Triacetate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Date Palm safety at a glance

Date Palm overall Generally safe Dates are safe as a food for most people when eaten in normal amounts.
Pregnancy Use caution Dates are a common food, but concentrated supplements or large amounts for inducing labor should be discussed with your doctor first.
Breastfeeding Use caution Eating dates as food is generally fine, but safety of concentrated supplements is not well studied.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Uridine Triacetate and Date Palm? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Date Palm Itself Has Been Linked To

This is not an interaction — nothing below involves Uridine Triacetate. It is the side-effect record for Date Palm on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Date Palm, this list is the first place to look. 2 entries are worth acting on rather than waiting out — marked below.

  • Wheezing Worth acting on Additional detail

    “By inhalation, date palm pollen has been reported to cause allergic rhinitis, wheezing, rhinoconjunctivitis, and bronchial asthma. Orally, date palm fruit has been reported to cause allergic reactions.”

    Date Palm · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    3 sources cited
    1. 30207. Bener, A., Safa, W., Abdulhalik, S., and Lestringant, G. G. An analysis of skin prick test reactions in asthmatics in a hot climate and desert environment. Allerg.Immunol.(Paris) 2002;34(8):281-286.
    2. 47102. Blanco, C., Carrillo, T., Quiralte, J., Pascual, C., Martin, Esteban M., and Castillo, R. Occupational rhinoconjunctivitis and bronchial asthma due to Phoenix canariensis pollen allergy. Allergy 1995;50(3):277-280.
    3. 30204. Kwaasi, A. A., Harfi, H. A., Parhar, R. S., Saleh, S., Collison, K. S., Panzani, R. C., Al Sedairy, S. T., and Al Mohanna, F. A. Cross-reactivities between date palm (Phoenix dactylifera L.) polypeptides and foods implicated in the oral allergy syndrome.
  • An allergic reaction Worth acting on Additional detail

    “Orally, date palm fruit is safe when consumed as a food. It has been reported to cause allergic reactions. Orally, date palm pollen appears to be generally well tolerated. When inhaled, allergy to date palm pollen is fairly common.”

    Date Palm · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    5 sources cited
    1. 30204. Kwaasi, A. A., Harfi, H. A., Parhar, R. S., Saleh, S., Collison, K. S., Panzani, R. C., Al Sedairy, S. T., and Al Mohanna, F. A. Cross-reactivities between date palm (Phoenix dactylifera L.) polypeptides and foods implicated in the oral allergy syndrome.
    2. 98654. Elkerm Y, Tawashi R. Date palm pollen as a preventative intervention in radiation- and chemotherapy-induced oral mucositis: a pilot study. Integr Cancer Ther. 2014;13(6):468-72. PubMed
    3. 98655. Rasekh A, Jashni HK, Rahmanian K, Jahromi AS. Effect of palm pollen on sperm parameters of infertile man. Pak J Biol Sci. 2015;18(4):196-9. PubMed
    4. 30207. Bener, A., Safa, W., Abdulhalik, S., and Lestringant, G. G. An analysis of skin prick test reactions in asthmatics in a hot climate and desert environment. Allerg.Immunol.(Paris) 2002;34(8):281-286.
    5. 47102. Blanco, C., Carrillo, T., Quiralte, J., Pascual, C., Martin, Esteban M., and Castillo, R. Occupational rhinoconjunctivitis and bronchial asthma due to Phoenix canariensis pollen allergy. Allergy 1995;50(3):277-280.
  • A stuffy or runny nose Additional detail

    Recorded for Date Palm in the same Natural Medicines adverse-effect record shown under Wheezing above.

Everything above comes from the Natural Medicines adverse-effect record for Date Palm — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Uridine Triacetate’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Uridine Triacetate column appears here.

How to take them

Some Uridine Triacetate Products Have a Food Rule — Date Palm Should Not Break It

At least one FDA label for a product containing Uridine Triacetate says to take it with food. If you take Date Palm on an empty stomach out of habit, keep them separate — and take Uridine Triacetate with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Uridine Triacetate products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Administer the dose with food (applesauce, pudding or yogurt) or in milk or infant formula.

From the Dosage and Administration section of the FDA label we read for Uridine Triacetate — where that label names a specific product, the instruction is that product's. See the Uridine Triacetate drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Uridine Triacetate

This page covers Date Palm only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Uridine Triacetate page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Uridine Triacetate page

“Uridine triacetate is a drug you take when absorption truly cannot fail, whether as Vistogard, the emergency antidote for fluorouracil or capecitabine overdose, or as Xuriden for hereditary orotic aciduria. That is why the 17 supplement interactions on file deserve real care rather than a shrug.”

Reviewed by 2 · Jul 18, 2026

Open the Uridine Triacetate interaction page

One more smart check

Taking Date Palm as Part of a Dietary Supplement Product? Check It for Interactions

We hold 112 real supplement products containing Date Palm, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Date Palm. Even though Date Palm itself has no known interaction with Uridine Triacetate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Date Palm and Uridine Triacetate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Date Palm
Steady interest

#986 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Uridine Triacetate
Steady interest

#2,711 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Date Palm reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Date Palm and Uridine Triacetate records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Date Palm

What is Date Palm?

  • Nutritional energy source
  • Digestive health and constipation
  • Labor support (folk use)
  • Male fertility (pollen, traditional)
  • General wellness and antioxidant support

Date palm fruit is a nutritious food rich in natural sugars, fiber, and antioxidants, and is widely eaten as part of a healthy diet. Beyond its value as food, evidence for medicinal benefits like easing labor or boosting fertility is limited and mostly preliminary. Talk to your pharmacist or doctor before using concentrated date supplements for a health condition.

Phoenix dactylifera · Arecaceae · Fruit (dates), seeds, pollen, and sometimes sap or flowers · Whole fruit, date syrup, date paste, seed powder, capsules, and pollen extracts

An interaction check asks whether these two react with each other — it does not ask whether Date Palm is a good idea for someone in your situation. Here is what our Date Palm record says about it on its own.

Date Palm: dosing

There is no official or standardized medicinal dose for date palm. As a food, dates are eaten according to personal taste and dietary needs, and a few dates make a typical serving.For date supplements, syrups, or pollen products, follow the directions on the product label.

From our Date Palm monograph — the full record covers uses, side effects and every documented interaction.

Read the full Date Palm monograph & all interactions
Medication

About Uridine Triacetate

What Is Uridine Triacetate Used For?

Brand names: Xuriden, Vistogard

Uridine triacetate is available as two different products for two distinct uses. Vistogard is used for emergency treatment after an overdose of the chemotherapy drugs fluorouracil or capecitabine — or when someone develops severe, early, or life-threatening side effects from those drugs (such as heart or nervous system problems, severe digestive reactions, or a dangerous drop in white blood cells) within 96 hours of their last dose.

Xuriden is used to treat hereditary orotic aciduria, a rare inherited condition in which the body cannot make enough of a building block called uridine, causing a buildup of orotic acid and problems with blood cell production and other body functions. Both products are approved for adults and children.

See full Uridine Triacetate drug information
Keep checking

Other Drugs & Date Palm

Browse every other medication we’ve checked against Date Palm — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Date Palm against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Date Palm list.

See the full Date Palm interactions page
See every supplement checked against Uridine Triacetate, ranked by severity
Evidence & sources

Date Palm References

The 9 references that drive our Date Palm monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Kwaasi, A. A., Harfi, H. A., Parhar, R. S., Saleh, S., Collison, K. S., Panzani, R. C., Al Sedairy, S. T., and Al Mohanna, F. A. Cross-reactivities between date palm (Phoenix dactylifera L.) polypeptides and foods implicated in the oral allergy syndrome.
  2. Bener, A., Safa, W., Abdulhalik, S., and Lestringant, G. G. An analysis of skin prick test reactions in asthmatics in a hot climate and desert environment. Allerg.Immunol.(Paris) 2002;34(8):281-286.
  3. Bauza, E., Dal Farra, C., Berghi, A., Oberto, G., Peyronel, D., and Domloge, N. Date palm kernel extract exhibits antiaging properties and significantly reduces skin wrinkles. Int.J.Tissue React. 2002;24(4):131-136.
  4. Blanco, C., Carrillo, T., Quiralte, J., Pascual, C., Martin, Esteban M., and Castillo, R. Occupational rhinoconjunctivitis and bronchial asthma due to Phoenix canariensis pollen allergy. Allergy 1995;50(3):277-280.
  5. Elkerm Y, Tawashi R. Date palm pollen as a preventative intervention in radiation- and chemotherapy-induced oral mucositis: a pilot study. Integr Cancer Ther. 2014;13(6):468-72. PubMed
  6. Rasekh A, Jashni HK, Rahmanian K, Jahromi AS. Effect of palm pollen on sperm parameters of infertile man. Pak J Biol Sci. 2015;18(4):196-9. PubMed
  7. Bagherzadeh Karimi A, Elmi A, Mirghafourvand M, Baghervand Navid R. Effects of date fruit (Phoenix dactylifera L.) on labor and delivery outcomes: a systematic review and meta-analysis. BMC Pregnancy Childbirth. 2020 Apr 14;20(1):210. PubMed
  8. Al Jaouni SK, Hussein A, Alghamdi N, et al. Effects of Phoenix dactylifera Ajwa on infection, hospitalization, and survival among pediatric cancer patients in a university hospital: A nonrandomized controlled trial. Integr Cancer Ther. 2019;18:15347354198
  9. Royani I, As'ad S, Mappaware NA, Hatta M, Rabia. Effect of Ajwa dates consumption to inhibit the progression of preeclampsia threats on mean arterial pressure and roll-over test. Biomed Res Int. 2019 Dec 10;2019:2917895. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Date Palm and Uridine Triacetate Together: Common Questions

Is it safe to take Date Palm with Uridine Triacetate?
We do not list a known interaction between Date Palm and Uridine Triacetate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Date Palm and Uridine Triacetate at the same time of day?
At least one FDA label for a product containing Uridine Triacetate says to take it with food. If you take Date Palm on an empty stomach out of habit, keep them separate and take Uridine Triacetate with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Uridine Triacetate products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Uridine Triacetate interact with any supplements?
Yes. Uridine Triacetate has documented interactions with 17 supplements in our database — Date Palm is not one of them. The Uridine Triacetate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Date Palm monograph Uses, safety profile, and every drug interaction in one place Uridine Triacetate drug information The full plain-English guide to this medication Uridine Triacetate supplement interactions Every supplement checked against Uridine Triacetate, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 9 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Uridine Triacetate and Date Palm?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.