Drug & supplement interaction

Desert Parsley + Naloxegol

Naloxegol brand name: Movantik.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Desert Parsley and Naloxegol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Naloxegol states a food rule worth keeping to.

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Interaction report

Desert Parsley and Naloxegol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Naloxegol and Desert Parsley in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Desert Parsley at all — not against Naloxegol, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Desert Parsley safety at a glance

Desert Parsley overall Use caution Limited human safety data and a known risk of a measles-like skin rash in some users.
Pregnancy Avoid Not enough safety data; avoid use during pregnancy.
Breastfeeding Avoid Not enough safety data; avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Naloxegol and Desert Parsley? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Naloxegol’s Own FDA Label Lists

This is not an interaction — none of it involves Desert Parsley. These are the most notable effects listed in the ADVERSE REACTIONS section of Naloxegol’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both.

  • Bloating or gas
  • Stomach pain mentioned in 12.5% of FDA reports for Naloxegol
  • Sweating
  • Diarrhea mentioned in 9.7% of FDA reports for Naloxegol
  • Nausea mentioned in 8.4% of FDA reports for Naloxegol
  • Vomiting
  • Headache

From the ADVERSE REACTIONS section of the FDA label for Naloxegol. Read the label on DailyMed › Where a percentage is shown, it is the share of 3,902 voluntary FDA FAERS reports for Naloxegol that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Desert Parsley’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Desert Parsley side to compare — that is a limit of the record, not a statement that Desert Parsley has no side effects.

How to take them

Some Naloxegol Products Have a Food Rule — Desert Parsley Should Not Break It

At least one FDA label for a product containing Naloxegol says to take it on an empty stomach. Most supplements — Desert Parsley included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Naloxegol on its own and move Desert Parsley to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Naloxegol products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

(2.1) Take on an empty stomach at least 1 hour prior to the first meal of the day or 2 hours after the meal.

From the Dosage and Administration section of the FDA label we read for Naloxegol — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Naloxegol

This page covers Desert Parsley only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Naloxegol page lists 138 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 94 moderate · 41 minor.

From our pharmacist’s overview on the Naloxegol page

“Naloxegol (Movantik) relieves the constipation that opioids cause, and this is a list that deserves real care before you add anything from it. Nearly all of the trouble traces to a single enzyme, CYP3A4, which the body relies on to clear naloxegol.”

Reviewed by 2 · Jul 18, 2026

Open the Naloxegol interaction page

How much people look this up

Where Desert Parsley and Naloxegol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Desert Parsley
Top half

#562 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Naloxegol
Steady interest

#1,429 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Desert Parsley is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Desert Parsley reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Desert Parsley and Naloxegol records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Desert Parsley

What is Desert Parsley?

  • Respiratory infections and colds
  • Cough and congestion
  • Flu-like illness
  • Immune support
  • Sore throat

Desert Parsley (Lomatium dissectum) is a root used in Native American and Western herbal traditions, mainly for colds, coughs, and respiratory infections. Modern scientific evidence in humans is very limited, and it can cause a widespread skin rash in some people, so use it cautiously and talk with your pharmacist or doctor first.

Lomatium dissectum · Apiaceae · Root · Tincture, capsules, dried root, tea, glycerite extract

An interaction check asks whether these two react with each other — it does not ask whether Desert Parsley is a good idea for someone in your situation. Here is what our Desert Parsley record says about it on its own.

Desert Parsley: dosing

There is no established standard dose for Desert Parsley. Traditional use varies widely depending on the form, whether it is a tincture, capsule, or tea.Because a safe and effective dose has not been defined in research, follow the directions on the product label and do not exceed them.

From our Desert Parsley monograph — the full record covers uses, side effects and every documented interaction.

Read the full Desert Parsley monograph & all interactions
Medication

About Naloxegol

What Is Naloxegol Used For?

Brand name: Movantik

Movantik (naloxegol) is used to treat opioid-induced constipation (OIC) — constipation caused by opioid pain medications — in adults who have chronic non-cancer pain. It is also approved for adults with chronic pain related to prior cancer or its treatment, as long as they don't need frequent (roughly weekly) increases in their opioid dose.

It is not indicated for constipation from other causes, and it is not approved for use in children.

Most-Reported Side Effects for Naloxegol

From FAERS, the FDA’s public side-effect reporting system (3,902 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Diarrhea 380 reports
Constipation 375 reports
Nausea 329 reports
Abdominal pain 258 reports
Abdominal pain upper 228 reports
See full Naloxegol drug information
Keep checking

Other Drugs & Desert Parsley

Browse every other medication we’ve checked against Desert Parsley — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Desert Parsley against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Desert Parsley list.

See the full Desert Parsley interactions page
See every supplement checked against Naloxegol, ranked by severity
Evidence & sources

Desert Parsley References

The 1 sources that drive our Desert Parsley monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Desert Parsley is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Using Dietary Supplements Wisely — NIH National Center for Complementary and Integrative Health (NCCIH) Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Desert Parsley and Naloxegol Together: Common Questions

Is it safe to take Desert Parsley with Naloxegol?
We do not list a known interaction between Desert Parsley and Naloxegol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Desert Parsley and Naloxegol at the same time of day?
At least one FDA label for a product containing Naloxegol says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Naloxegol on its own and move Desert Parsley to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
Does Naloxegol interact with any supplements?
Yes. Naloxegol has documented interactions with 138 supplements in our database — Desert Parsley is not one of them. The Naloxegol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Desert Parsley monograph Uses, safety profile, and every drug interaction in one place Naloxegol drug information The full plain-English guide to this medication Naloxegol supplement interactions Every supplement checked against Naloxegol, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Naloxegol and Desert Parsley?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.