Drug & supplement interaction

Diacylglycerol + Amphetamine

Amphetamine brand names: Dyanavel XR, Adensys XR-ODT, Mydayis, Adzenys ER.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Diacylglycerol and Amphetamine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Diacylglycerol and Amphetamine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Amphetamine and Diacylglycerol in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Diacylglycerol at all — not against Amphetamine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Diacylglycerol safety at a glance

Diacylglycerol overall Use caution Considered a normal dietary fat, but health-benefit claims are unproven and one commercial product faced a contaminant recall.
Pregnancy Likely Safe When used orally in the amounts found in foods. There is insufficient reliable information available about the safety of diacylglycerol when used in larger amou... Read the full pregnancy detail
Breastfeeding Likely Safe When used orally in the amounts found in foods. There is insufficient reliable information available about the safety of diacylglycerol when used in larger amou... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Amphetamine and Diacylglycerol? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
Special populations

Diacylglycerol in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When used orally in the amounts found in foods. There is insufficient reliable information available about the safety of diacylglycerol when used in larger amounts during pregnancy and lactation.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Amphetamine Is Prescribed For, and What Diacylglycerol Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Amphetamine is a prescription medicine with approved uses on its FDA label. Diacylglycerol is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Amphetamine is prescribed for: Amphetamine treats Attention Deficit Hyperactivity Disorder (ADHD) in patients 6 years and older. Adzenys XR-ODT, Dyanavel XR, and the amphetamine extended-release orally disintegrating tablet formulations are specifically approved for ADHD in this age group. Amphetamine Sulfate tablets and Evekeo (amphetamine sulfate tablets) are also approved for narcolepsy (a sleep disorder causing uncontrollable daytime sleepiness) and as a short-term aid in a calorie-restricted weight-loss program for exogenous obesity (weight gain from external factors like overeating) in patients who have not responded to other approaches.

Diacylglycerol has been studied for:

  • Obesity Natural Medicines rates the evidence for Diacylglycerol: Possibly Effective Read what the research shows

    Diacylglycerol for obesity

    Most clinical research shows that oral diacylglycerol improves body weight and/or body composition in overweight or obese individuals.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Amphetamine on your own; if you are taking Diacylglycerol for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Diacylglycerol or Amphetamine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Diacylglycerol or Amphetamine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Amphetamine

This page covers Diacylglycerol only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Amphetamine page lists 130 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Bitter Orange (major), Brewer's Yeast (major) and Cowhage (major).

By severity: 16 major · 97 moderate · 17 minor.

From our pharmacist’s overview on the Amphetamine page

“Amphetamine (Dyanavel XR, Adzenys ER, Mydayis) is a prescription stimulant, usually taken for ADHD, and its interaction list is one to approach with genuine care. Of the 130 supplements and herbal ingredients on file, 16 carry a major rating, and many of those work the same way, either inhibiting monoamine oxidase, as yohimbe does, or…”

Reviewed by 2 · Jul 18, 2026

Open the Amphetamine interaction page

One more smart check

Taking Diacylglycerol as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Diacylglycerol, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Diacylglycerol. Even though Diacylglycerol itself has no known interaction with Amphetamine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Diacylglycerol and Amphetamine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Diacylglycerol
Steady interest

#1,285 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Amphetamine
Top 5%

#45 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Diacylglycerol is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Diacylglycerol reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Diacylglycerol and Amphetamine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Diacylglycerol

What is Diacylglycerol?

  • Weight management
  • Reducing body fat
  • Lowering blood triglycerides
  • Healthy cooking oil substitute

Diacylglycerol (DAG) is a type of fat found naturally in small amounts in many edible oils and was once sold as a specialty cooking oil marketed for weight and fat management. Evidence for meaningful weight-loss benefits over regular cooking oils is weak and mixed, and one major DAG oil product was pulled from the market over a processing-related contaminant concern. Talk with your pharmacist or doctor before relying on it for any health purpose.

Edible oil component (derived from vegetable oils such as soybean and rapeseed) · Cooking oil, salad dressings, and processed food products

An interaction check asks whether these two react with each other — it does not ask whether Diacylglycerol is a good idea for someone in your situation. Here is what our Diacylglycerol record says about it on its own.

Diacylglycerol: dosing

There is no established or standardized dose of diacylglycerol for any health benefit. When sold as a cooking oil, it was simply used in place of regular oil in everyday cooking.If you come across a diacylglycerol product, follow the label directions and do not assume that using more will give you any extra benefit.

From our Diacylglycerol monograph — the full record covers uses, side effects and every documented interaction.

Read the full Diacylglycerol monograph & all interactions
Medication

About Amphetamine

What Is Amphetamine Used For?

Brand names: Dyanavel XR, Adensys XR-ODT, Mydayis, Adzenys ER

Amphetamine treats Attention Deficit Hyperactivity Disorder (ADHD) in patients 6 years and older. Adzenys XR-ODT, Dyanavel XR, and the amphetamine extended-release orally disintegrating tablet formulations are specifically approved for ADHD in this age group.

Amphetamine Sulfate tablets and Evekeo (amphetamine sulfate tablets) are also approved for narcolepsy (a sleep disorder causing uncontrollable daytime sleepiness) and as a short-term aid in a calorie-restricted weight-loss program for exogenous obesity (weight gain from external factors like overeating) in patients who have not responded to other approaches.

See full Amphetamine drug information
Keep checking

Other Drugs & Diacylglycerol

Browse every other medication we’ve checked against Diacylglycerol — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Diacylglycerol against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Diacylglycerol list.

See the full Diacylglycerol interactions page
See every supplement checked against Amphetamine, ranked by severity
Evidence & sources

Diacylglycerol References

The 1 sources that drive our Diacylglycerol monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Diacylglycerol is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Dietary Fats Explained — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Diacylglycerol and Amphetamine Together: Common Questions

Is it safe to take Diacylglycerol with Amphetamine?
We do not list a known interaction between Diacylglycerol and Amphetamine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Diacylglycerol and Amphetamine used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Diacylglycerol in each. That is a conversation for your prescriber, especially if Amphetamine is being adjusted to a target.
Does Amphetamine interact with any supplements?
Yes. Amphetamine has documented interactions with 130 supplements in our database — Diacylglycerol is not one of them. The Amphetamine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Diacylglycerol monograph Uses, safety profile, and every drug interaction in one place Amphetamine drug information The full plain-English guide to this medication Amphetamine supplement interactions Every supplement checked against Amphetamine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Amphetamine and Diacylglycerol?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.