Drug & supplement interaction

Dimethylglycine (dmg) + Chlordiazepoxide, Clidinium Bromide

Chlordiazepoxide, Clidinium Bromide brand name: Librax.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Dimethylglycine (dmg) and Chlordiazepoxide, Clidinium Bromide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Dimethylglycine (dmg) and Chlordiazepoxide, Clidinium Bromide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Chlordiazepoxide, Clidinium Bromide and Dimethylglycine (dmg) in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Dimethylglycine (dmg) at all — not against Chlordiazepoxide, Clidinium Bromide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Dimethylglycine (dmg) safety at a glance

Dimethylglycine (d... overall Use caution Appears generally well tolerated short-term, but high-quality long-term safety data are limited.
Pregnancy Avoid Not enough safety information; best to avoid during pregnancy.
Breastfeeding Avoid No reliable safety data, so avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Chlordiazepoxide, Clidinium Bromide and Dimethylglycine (dmg)? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Chlordiazepoxide, Clidinium Bromide’s Own FDA Label Lists

This is not an interaction — none of it involves Dimethylglycine (dmg). These are the most notable effects listed in the ADVERSE REACTIONS section of Chlordiazepoxide, Clidinium Bromide’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 5 of them are worth acting on rather than waiting out — marked below.

  • Unsteadiness Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • Fainting Worth acting on
  • Confusion Worth acting on
  • A low white blood cell count Worth acting on
  • Changes to your period
  • A change in sex drive
  • Drowsiness
  • Constipation
  • Swelling

Showing the 10 most notable of 11 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Chlordiazepoxide, Clidinium Bromide. Read the label on DailyMed › Dimethylglycine (dmg)’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Dimethylglycine (dmg) side to compare — that is a limit of the record, not a statement that Dimethylglycine (dmg) has no side effects.

Overlapping uses

What Chlordiazepoxide, Clidinium Bromide Is Prescribed For, and What Dimethylglycine (dmg) Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Chlordiazepoxide, Clidinium Bromide is a prescription medicine with approved uses on its FDA label. Dimethylglycine (dmg) is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Chlordiazepoxide, Clidinium Bromide is prescribed for: This combination is used to control emotional and somatic (physical) factors in gastrointestinal disorders. In plain terms, it targets digestive problems where stress or nerves play a part. It may also be used as add-on treatment for peptic ulcer, irritable bowel syndrome (irritable colon, spastic colon, mucous colitis) and acute enterocolitis (sudden inflammation of the small intestine and colon). The label lists these same uses for the generic capsules and for Librax.

Dimethylglycine (dmg) has been studied for:

  • Stress studied, not established Dimethylglycine (dmg) has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Dimethylglycine (dmg) for stress

    Although there has been interest in using oral dimethylglycine for stress, there is insufficient reliable information about the clinical effects of dimethylglycine for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Chlordiazepoxide, Clidinium Bromide on your own; if you are taking Dimethylglycine (dmg) for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Chlordiazepoxide, Clidinium Bromide

This page covers Dimethylglycine (dmg) only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Chlordiazepoxide, Clidinium Bromide page lists 188 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Grapefruit (major).

By severity: 10 major · 142 moderate · 36 minor.

From our pharmacist’s overview on the Chlordiazepoxide, Clidinium Bromide page

“Librax combines chlordiazepoxide, a benzodiazepine, with clidinium, an anticholinergic, and both halves interact with supplements, 188 ingredients in all. This is a list to approach with real care, starting with the 10 rated major.”

Reviewed by 2 · Jul 18, 2026

Open the Chlordiazepoxide, Clidinium Bromide interaction page

How much people look this up

Where Dimethylglycine (dmg) and Chlordiazepoxide, Clidinium Bromide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Dimethylglycine (dmg)
Steady interest

#1,063 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Chlordiazepoxide, Clidinium Bromide
Top half

#1,305 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Dimethylglycine (dmg) is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Dimethylglycine (dmg) reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Dimethylglycine (dmg) and Chlordiazepoxide, Clidinium Bromide records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Dimethylglycine (dmg)

What is Dimethylglycine (dmg)?

  • Athletic performance and energy
  • Autism spectrum support
  • Immune support
  • Seizure disorders
  • General wellness and detox support

Dimethylglycine (DMG) is a substance made naturally in the body and found in small amounts in foods. It is marketed for energy, athletic performance, autism, and immune support, but solid human evidence for most of these uses is limited. It appears generally well tolerated in short-term use, but talk with your pharmacist or doctor before trying it.

Not applicable (a naturally occurring amino acid derivative) · Tablets, capsules, chewable tablets, sublingual tablets, powder

An interaction check asks whether these two react with each other — it does not ask whether Dimethylglycine (dmg) is a good idea for someone in your situation. Here is what our Dimethylglycine (dmg) record says about it on its own.

Dimethylglycine (dmg): dosing

There is no officially established or standardized dose of DMG. Products vary widely in strength and in the directions they give.The safest approach is to follow the dosing instructions on the product label and not exceed them. If you do not notice a clear benefit, there is no reason to keep taking it.

From our Dimethylglycine (dmg) monograph — the full record covers uses, side effects and every documented interaction.

Read the full Dimethylglycine (dmg) monograph & all interactions
Medication

About Chlordiazepoxide and Clidinium

What Is Chlordiazepoxide and Clidinium Used For?

Brand name: Librax

This combination is used to control emotional and somatic (physical) factors in gastrointestinal disorders. In plain terms, it targets digestive problems where stress or nerves play a part.

It may also be used as add-on treatment for peptic ulcer, irritable bowel syndrome (irritable colon, spastic colon, mucous colitis) and acute enterocolitis (sudden inflammation of the small intestine and colon). The label lists these same uses for the generic capsules and for Librax.

See full Chlordiazepoxide and Clidinium drug information
Keep checking

Other Drugs & Dimethylglycine (dmg)

Browse every other medication we’ve checked against Dimethylglycine (dmg) — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Dimethylglycine (dmg) References

The 2 sources that drive our Dimethylglycine (dmg) monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Dimethylglycine (dmg) is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  2. Using Dietary Supplements Wisely — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Dimethylglycine (dmg) and Chlordiazepoxide, Clidinium Bromide Together: Common Questions

Is it safe to take Dimethylglycine (dmg) with Chlordiazepoxide, Clidinium Bromide?
We do not list a known interaction between Dimethylglycine (dmg) and Chlordiazepoxide, Clidinium Bromide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Dimethylglycine (dmg) and Chlordiazepoxide, Clidinium Bromide used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Dimethylglycine (dmg) in each. That is a conversation for your prescriber, especially if Chlordiazepoxide, Clidinium Bromide is being adjusted to a target.
Does Chlordiazepoxide, Clidinium Bromide interact with any supplements?
Yes. Chlordiazepoxide, Clidinium Bromide has documented interactions with 188 supplements in our database — Dimethylglycine (dmg) is not one of them. The Chlordiazepoxide, Clidinium Bromide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Chlordiazepoxide, Clidinium Bromide and Dimethylglycine (dmg)?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.