Medication interaction hub

What Supplements Interact with Chlordiazepoxide, Clidinium Bromide?

Chlordiazepoxide, Clidinium Bromide brand name: Librax. Every interaction below applies to the brands too.

188 Interactions 10 Major 142 Moderate 36 Minor
Curated & coded by · Clinical Pharmacist · Updated September 25, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Chlordiazepoxide, Clidinium Bromide? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Chlordiazepoxide, Clidinium Bromide against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Librax combines chlordiazepoxide, a benzodiazepine, with clidinium, an anticholinergic, and both halves interact with supplements, 188 ingredients in all. This is a list to approach with real care, starting with the 10 rated major. The largest cluster, 78 ingredients, adds sedation on top of the drug's own, and that includes kava and anything alcoholic (beer and wine both carry major ratings). Grapefruit also rates major because it can raise blood levels of some benzodiazepines. Another 30 entries, henbane among them, stack anticholinergic side effects like dry mouth, blurred vision, and constipation.

Most of the remaining 142 moderate entries share a liver pathway called CYP1A2, meaning levels of one thing or the other can shift. Seventeen can blunt absorption of oral doses, activated charcoal most of all, so space those far from your dose. Know the ten majors before you add anything sedating.

— , Clinical Pharmacist · July 18, 2026

Major 10 Moderate 142 Minor 36 No known interaction 1,264

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Chlordiazepoxide, Clidinium Bromide: Top Interactions at a Glance

The most significant Chlordiazepoxide, Clidinium Bromide supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 188 interacting ingredients — plus 1,264 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant Chlordiazepoxide, Clidinium Bromide + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Likely Beer + Chlordiazepoxide, Clidinium Bromidei

Concomitant use may increase sedative and other adverse effects.

Read the full interaction Major Likelihood Likely Grapefruit + Chlordiazepoxide, Clidinium Bromidei

Grapefruit juice might increase blood levels of some oral benzodiazepines, potentially increasing the effects and adverse effects of these drugs.

Read the full interaction Major Likelihood Likely Wine + Chlordiazepoxide, Clidinium Bromidei

Concomitant use may increase sedative and other adverse effects.

Read the full interaction Major Likelihood Probable 1,4-butanediol + Chlordiazepoxide, Clidinium Bromidei

Theoretically, concomitant use of 1,4-butanediol with CNS depressants may potentiate respiratory and CNS depression.

Read the full interaction Major Likelihood Probable Activated Charcoal + Chlordiazepoxide, Clidinium Bromidei

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.

Read the full interaction Major Likelihood Probable Gamma-hydroxybutyrate (ghb) + Chlordiazepoxide, Clidinium Bromidei

GHB may increase the risk of serious CNS and respiratory depression.

Read the full interaction
The complete list

Every Supplement Checked Against Chlordiazepoxide, Clidinium Bromide

All 1,452 ingredients in our database, ranked by severity — 188 with a Chlordiazepoxide, Clidinium Bromide interaction on file and 1,264 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Chlordiazepoxide, Clidinium Bromide?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Slippery Elm with Chlordiazepoxide, Clidinium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.

Full Slippery Elm + Chlordiazepoxide, Clidinium Bromide answer

Can you take Boswellia Serrata with Chlordiazepoxide, Clidinium Bromide?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.

Full Boswellia Serrata + Chlordiazepoxide, Clidinium Bromide answer

Can you take Beet with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.

Full Beet + Chlordiazepoxide, Clidinium Bromide answer

Can you take Black Pepper with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, black pepper might decrease levels and clinical effects of drugs metabolized by CYP1A2.

Full Black Pepper + Chlordiazepoxide, Clidinium Bromide answer

Can you take Black Psyllium with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Full Black Psyllium + Chlordiazepoxide, Clidinium Bromide answer

Can you take Blond Psyllium with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Full Blond Psyllium + Chlordiazepoxide, Clidinium Bromide answer

Can you take Broccoli Sprout with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.

Full Broccoli Sprout + Chlordiazepoxide, Clidinium Bromide answer

Can you take Calea Zacatechichi with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, Calea zacatechichi might increase the sedative effects of CNS depressants.

Full Calea Zacatechichi + Chlordiazepoxide, Clidinium Bromide answer

Can you take Carob with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, carob might also impair the absorption of oral drugs.

Full Carob + Chlordiazepoxide, Clidinium Bromide answer

Can you take Eurycoma Longifolia with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.

Full Eurycoma Longifolia + Chlordiazepoxide, Clidinium Bromide answer

Can you take Ginger with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, ginger might increase the levels of CYP1A2 substrates.

Full Ginger + Chlordiazepoxide, Clidinium Bromide answer

Can you take Hemp with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.

Full Hemp + Chlordiazepoxide, Clidinium Bromide answer

Can you take Hibiscus Sabdariffa with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, Hibiscus sabdariffa extract might reduce the metabolism of CYP1A2 substrates.

Full Hibiscus Sabdariffa + Chlordiazepoxide, Clidinium Bromide answer

Can you take Karaya Gum with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Co-administration of oral drugs with bulk forming laxatives such as karaya gum may decrease, increase, or have no effect on the absorption o...

Full Karaya Gum + Chlordiazepoxide, Clidinium Bromide answer

Can you take Licorice with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.

Full Licorice + Chlordiazepoxide, Clidinium Bromide answer

Can you take Marshmallow with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, mucilage in marshmallow might impair absorption of oral drugs.

Full Marshmallow + Chlordiazepoxide, Clidinium Bromide answer

Can you take Moringa with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.

Full Moringa + Chlordiazepoxide, Clidinium Bromide answer

Can you take Peppermint with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, peppermint might increase the levels of CYP1A2 substrates.

Full Peppermint + Chlordiazepoxide, Clidinium Bromide answer

Can you take Rhodiola with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, rhodiola might increase the risk of adverse effects when taken with CNS depressants.

Full Rhodiola + Chlordiazepoxide, Clidinium Bromide answer

Can you take Turmeric with Chlordiazepoxide, Clidinium Bromide?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, turmeric might increase levels of drugs metabolized by CYP1A2.

Full Turmeric + Chlordiazepoxide, Clidinium Bromide answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Chlordiazepoxide, Clidinium Bromide is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Chlordiazepoxide, Clidinium Bromide, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Chlordiazepoxide, Clidinium Bromide sits in 6 interaction categories. Open any one to see what the group means:

Cytochrome P450 1A2 (Cyp1A2) Substrates 79 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

79 of the supplement ingredients on this page reach Chlordiazepoxide, Clidinium Bromide through this category.

Cns Depressants 78 ingredients

Central-nervous-system depressants. Sedating supplements can intensify drowsiness and slowed reactions when combined.

78 of the supplement ingredients on this page reach Chlordiazepoxide, Clidinium Bromide through this category.

Anticholinergic Drugs 30 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

30 of the supplement ingredients on this page reach Chlordiazepoxide, Clidinium Bromide through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Chlordiazepoxide, Clidinium Bromide through this category.

Benzodiazepines 8 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

8 of the supplement ingredients on this page reach Chlordiazepoxide, Clidinium Bromide through this category.

Cytochrome P450 1A2 (Cyp1A2) Substrates 1 ingredient

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

1 of the supplement ingredient on this page reaches Chlordiazepoxide, Clidinium Bromide through this category.

About Chlordiazepoxide, Clidinium Bromide

Chlordiazepoxide and clidinium is a combination of a benzodiazepine and an anticholinergic used to treat gastrointestinal disorders, including irritable bowel syndrome and peptic ulcer, by addressing both the physical symptoms and the emotional factors that go with them.

Generic name: Chlordiazepoxide, Clidinium Bromide  ·  Brand name: Librax.

See the full Chlordiazepoxide and Clidinium drug information
Check a real product

Take a Supplement Product? Check the Whole Bottle Against Chlordiazepoxide, Clidinium Bromide

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Chlordiazepoxide, Clidinium Bromide.

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Products that contain Chlordiazepoxide, Clidinium Bromide-interacting ingredients

Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Chlordiazepoxide, Clidinium Bromide.

Yeast-Cleanse by Solaray contains Grapefruit Ultimate GCB by M3 Supplement Company contains Grapefruit Neuro Health by Nature’s Craft contains Grapefruit NDF Happy Peach by Bioray Kids contains Grapefruit
Pharmacist Counseling Corner

Chlordiazepoxide, Clidinium Bromide & Supplements: Common Questions

What supplements interact with Chlordiazepoxide, Clidinium Bromide?
In our interaction database, 188 supplement and herbal ingredients have an interaction with Chlordiazepoxide, Clidinium Bromide on file — 10 rated major, 142 moderate, and 36 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Beer, Grapefruit, Wine.
Which Chlordiazepoxide, Clidinium Bromide supplement interactions are the most serious?
The 10 major-rated combinations — led by Beer, Grapefruit, Wine, 1,4-butanediol and Activated Charcoal — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Chlordiazepoxide, Clidinium Bromide?
That depends entirely on which supplement. The honest answer for Chlordiazepoxide, Clidinium Bromide is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Librax have the same supplement interactions as Chlordiazepoxide, Clidinium Bromide?
Yes — Librax all contain Chlordiazepoxide, Clidinium Bromide, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Chlordiazepoxide, Clidinium Bromide and my other medications?
This page covers Chlordiazepoxide, Clidinium Bromide against supplements and herbal ingredients. Checking Chlordiazepoxide, Clidinium Bromide against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Chlordiazepoxide and Clidinium drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 25, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.