Drug & supplement interaction

English Adder's Tongue + Milrinone

Milrinone brand name: Primacor.

No Known Interaction
The bottom line No known interaction

We found no known interaction between English Adder's Tongue and Milrinone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

English Adder's Tongue and Milrinone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Milrinone and English Adder's Tongue in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for English Adder's Tongue at all — not against Milrinone, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

English Adder's Tongue safety at a glance

English Adder's To... overall Not established Very little modern safety data exists, so caution is warranted, especially when taken by mouth.
Pregnancy Avoid There is no reliable safety data, so it is best avoided during pregnancy.
Breastfeeding Avoid There is no reliable safety data, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Milrinone and English Adder's Tongue? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Milrinone’s Own FDA Label Lists

This is not an interaction — none of it involves English Adder's Tongue. These are the most notable effects listed in the ADVERSE REACTIONS section of Milrinone’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 6 of them are worth acting on rather than waiting out — marked below.

  • Low potassium Worth acting on
  • An irregular heartbeat Worth acting on mentioned in 3.7% of FDA reports for Milrinone
  • Wheezing Worth acting on
  • Chest pain Worth acting on
  • A low platelet count Worth acting on
  • A severe allergic reaction Worth acting on
  • Tremor or shakiness
  • Low blood pressure mentioned in 5.9% of FDA reports for Milrinone
  • A fast or pounding heartbeat mentioned in 3.7% of FDA reports for Milrinone
  • A skin rash

Showing the 10 most notable of 11 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Milrinone. Read the label on DailyMed › Where a percentage is shown, it is the share of 269 voluntary FDA FAERS reports for Milrinone that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. English Adder's Tongue’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no English Adder's Tongue side to compare — that is a limit of the record, not a statement that English Adder's Tongue has no side effects.

Everything else you take

See Every Supplement That Interacts With Milrinone

This page covers English Adder's Tongue only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Milrinone page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Milrinone page

“Milrinone (Primacor) strengthens the pumping of a failing heart, usually given by IV to seriously ill patients, which leaves little margin for a supplement quietly undercutting it. This list earns genuine care.”

Reviewed by 2 · Jul 18, 2026

Open the Milrinone interaction page

How much people look this up

Where English Adder's Tongue and Milrinone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement English Adder's Tongue
Steady interest

#1,430 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Milrinone
Top half

#823 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. English Adder's Tongue is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every English Adder's Tongue reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The English Adder's Tongue and Milrinone records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About English Adder's Tongue

What is English Adder's Tongue?

  • Minor wounds and skin irritation
  • Bruises and swelling
  • Insect bites
  • Soothing inflamed skin
  • Traditional eye washes (historical)

English Adder's Tongue is a small fern long used in folk medicine as a topical remedy for wounds, bruises, and skin irritation. There is very little modern scientific research to show whether it works or how safe it is, so use it cautiously and treat any health claims with skepticism.

Ophioglossum vulgatum · Ophioglossaceae · Leaves (fronds), sometimes the whole plant · Fresh leaves, salve or ointment, poultice, infused oil, tea

An interaction check asks whether these two react with each other — it does not ask whether English Adder's Tongue is a good idea for someone in your situation. Here is what our English Adder's Tongue record says about it on its own.

English Adder's Tongue: dosing

There is no established standardized dose for English Adder's Tongue. Traditional use focused on topical salves and poultices made from the fresh leaves, with no precise measured amounts.If you find a commercial product, follow the directions on the label and do not exceed them.

From our English Adder's Tongue monograph — the full record covers uses, side effects and every documented interaction.

Read the full English Adder's Tongue monograph & all interactions
Medication

About Milrinone

What Is Milrinone Used For?

Brand name: Primacor

Milrinone Lactate Injection and Milrinone Lactate in 5% Dextrose Injection are indicated for the short-term intravenous treatment of acute decompensated heart failure — a sudden or rapidly worsening episode of heart failure that requires immediate, in-hospital care.

This medication is given only in a monitored hospital setting. It is not intended for long-term or home use. Most clinical experience has been in patients who were also taking digoxin and diuretics (water pills).

Most-Reported Side Effects for Milrinone

From FAERS, the FDA’s public side-effect reporting system (271 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Hypotension 16 reports
Renal failure 13 reports
Cardiac failure 12 reports
Dyspnea 11 reports
Cardiac arrest 10 reports
See full Milrinone drug information
Keep checking

Other Drugs & English Adder's Tongue

Browse every other medication we’ve checked against English Adder's Tongue — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

English Adder's Tongue References

The 2 sources that drive our English Adder's Tongue monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. English Adder's Tongue is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbs and Supplements — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking English Adder's Tongue and Milrinone Together: Common Questions

Is it safe to take English Adder's Tongue with Milrinone?
We do not list a known interaction between English Adder's Tongue and Milrinone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Milrinone interact with any supplements?
Yes. Milrinone has documented interactions with 17 supplements in our database — English Adder's Tongue is not one of them. The Milrinone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Milrinone and English Adder's Tongue?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.