Drug & supplement interaction

Euphorbia Cyparissias + Digoxin

Digoxin brand names: Lanoxicaps, Lanoxin, Digitek.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 27, 2026
The bottom line No known interaction

We found no known interaction between Euphorbia Cyparissias and Digoxin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Euphorbia Cyparissias and Digoxin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Digoxin and Euphorbia Cyparissias in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Euphorbia Cyparissias at all — not against Digoxin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Euphorbia Cyparissias safety at a glance

Euphorbia Cypariss... overall Avoid The plant's latex is toxic and irritating, with little evidence of safe medicinal use.
Pregnancy Unsafe When used orally due to toxicity; avoid using. Read the full pregnancy detail
Breastfeeding Unsafe When used orally due to toxicity; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Digoxin and Euphorbia Cyparissias? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Euphorbia Cyparissias and Digoxin May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Blurred vision Additional detail

    Euphorbia Cyparissias

    “A case report describes an 82-year-old female who touched the eye with Euphorbia cyparissias latex while gardening and presented with redness, hyperemia, and excessive watering of the eyes, blurred vision, photophobia, and rhinorrhea.”

    Euphorbia Cyparissias · Natural Medicines adverse-effect record, reported in pregnancy-related edema.

    1 source cited
    1. 96556. Fleischman D, Meyer JJ, Fowler WC. Keratouveitis from Euphorbia cyparissias exposure is a temporal phenomenon. Clin Ophthalmol 2012;6:851-3. doi: 10.2147/OPTH.S32209. PubMed

    Digoxin

    Listed in the ADVERSE REACTIONS section of the FDA label for Digoxin. Read the label on DailyMed ›

  • Diarrhea / Vomiting Additional detail

    Euphorbia Cyparissias

    “Orally, latex from Euphorbia cyparissias causes burning of the mouth, vomiting, and diarrhea (18).”

    Euphorbia Cyparissias · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    Digoxin

    Listed in the ADVERSE REACTIONS section of the FDA label for Digoxin. Read the label on DailyMed ›

Reported for Euphorbia Cyparissias but not commonly for Digoxin: itching and swelling.

Effects for Digoxin come from the ADVERSE REACTIONS section of its FDA label; effects for Euphorbia Cyparissias come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Euphorbia Cyparissias in Pregnancy & Breastfeeding

Pregnancy And Lactation Unsafe

When used orally due to toxicity; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Euphorbia Cyparissias or Digoxin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Euphorbia Cyparissias or Digoxin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Digoxin

This page covers Euphorbia Cyparissias only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Digoxin page lists 113 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Aloe (major), Blue Flag (major), Danshen (major) and European Buckthorn (major).

By severity: 18 major · 79 moderate · 16 minor.

From our pharmacist’s overview on the Digoxin page

“Digoxin is a heart medicine with a narrow therapeutic index, meaning the gap between a helpful blood level and a harmful one is small, and few drugs give me more pause when supplements enter the picture. The most serious entries here are herbs that themselves contain digoxin-like cardiac glycosides, foxglove and lily-of-the-valley amon…”

Reviewed by 2 · Jul 18, 2026

Open the Digoxin interaction page

How much people look this up

Where Euphorbia Cyparissias and Digoxin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Euphorbia Cyparissias
Steady interest

#1,446 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Digoxin
Top 25%

#353 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Euphorbia Cyparissias reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Euphorbia Cyparissias and Digoxin records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Euphorbia Cyparissias

What is Euphorbia Cyparissias?

  • Constipation (as a harsh purgative)
  • Skin warts and corns
  • Folk remedy for swelling or growths
  • Traditional homeopathic use

Euphorbia cyparissias (cypress spurge) is a wild plant with a toxic, irritating milky sap that has been used in folk medicine as a purgative and to treat warts. There is no reliable evidence that it is safe or effective for any condition, and its latex can cause serious skin, eye, and digestive harm. We do not recommend using it; talk to a pharmacist or doctor before considering any spurge product.

Euphorbia cyparissias · Euphorbiaceae · Whole flowering plant and its milky latex (sap) · Dried herb, tincture, homeopathic preparations; topical applications of the fresh latex

An interaction check asks whether these two react with each other — it does not ask whether Euphorbia Cyparissias is a good idea for someone in your situation. Here is what our Euphorbia Cyparissias record says about it on its own.

Euphorbia Cyparissias: dosing

There is no established or safe dose for Euphorbia cyparissias. It is not a standardized supplement, and because the plant is toxic, we do not recommend taking it. Homeopathic products are extremely diluted, but their safety and effectiveness are also not well studied.If you come across any product containing this plant, do not guess at an amount. Follow the product label only after checking with a pharmacist or doctor, and never apply the raw sap to your skin or take the plant by mouth on your own.

From our Euphorbia Cyparissias monograph — the full record covers uses, side effects and every documented interaction.

Read the full Euphorbia Cyparissias monograph & all interactions
Medication

About Digoxin

What Is Digoxin Used For?

Brand names: Lanoxicaps, Lanoxin, Digitek

Digoxin tablets, oral solution, and injections (including Lanoxin brand) are all approved to treat mild to moderate heart failure in adults — improving symptoms like exercise tolerance and reducing hospitalizations, though it does not extend life. It is also approved to control the resting ventricular rate (how fast the lower chambers beat) in adults with chronic atrial fibrillation. The oral solution specifically notes it should not be used for multifocal atrial tachycardia.

In children with heart failure, digoxin is used to strengthen the heart's contractions (increase myocardial contractility). Digoxin is best used alongside a diuretic (water pill) and an ACE inhibitor when possible.

Most-Reported Side Effects for Digoxin

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dyspnea 6,169 reports
Nausea 4,831 reports
Dizziness 4,531 reports
Fatigue 4,262 reports
Atrial fibrillation 4,040 reports
See full Digoxin drug information
Keep checking

Other Drugs & Euphorbia Cyparissias

Browse every other medication we’ve checked against Euphorbia Cyparissias — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Euphorbia Cyparissias against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Euphorbia Cyparissias list.

See the full Euphorbia Cyparissias interactions page
See every supplement checked against Digoxin, ranked by severity
Evidence & sources

Euphorbia Cyparissias References

The 2 references that drive our Euphorbia Cyparissias monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Fleischman D, Meyer JJ, Fowler WC. Keratouveitis from Euphorbia cyparissias exposure is a temporal phenomenon. Clin Ophthalmol 2012;6:851-3. doi: 10.2147/OPTH.S32209. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Euphorbia Cyparissias and Digoxin Together: Common Questions

Is it safe to take Euphorbia Cyparissias with Digoxin?
We do not list a known interaction between Euphorbia Cyparissias and Digoxin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Euphorbia Cyparissias and Digoxin have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Digoxin interact with any supplements?
Yes. Digoxin has documented interactions with 113 supplements in our database — Euphorbia Cyparissias is not one of them. The Digoxin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Euphorbia Cyparissias monograph Uses, safety profile, and every drug interaction in one place Digoxin drug information The full plain-English guide to this medication Digoxin supplement interactions Every supplement checked against Digoxin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Digoxin and Euphorbia Cyparissias?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.