Drug & supplement interaction

Feingold Diet + Divalproex Sodium

Divalproex Sodium brand name: Depakote.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Feingold Diet and Divalproex Sodium in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Feingold Diet and Divalproex Sodium

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Divalproex Sodium and Feingold Diet in our sources. This does not guarantee that the combination is completely free of risk — research on Feingold Diet alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Feingold Diet at all — not against Divalproex Sodium, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Feingold Diet is an eating pattern rather than something you take. Ask your pharmacist or doctor before changing how you eat while on a prescribed medicine: some medicines are dosed around meals, and a change in diet can change how they work. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Feingold Diet safety at a glance

Feingold Diet overall Use caution Generally low risk, but restrictive diets in children can lead to nutrition gaps if not supervised.
Pregnancy Use caution The diet is aimed at children; pregnant people should not follow restrictive diets without medical guidance.
Breastfeeding Use caution Restricting your own diet while breastfeeding is not recommended without a clinician's advice.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Divalproex Sodium and Feingold Diet? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Divalproex Sodium’s Own FDA Label Lists

This is not an interaction — none of it involves Feingold Diet. These are the most notable effects listed in the ADVERSE REACTIONS section of Divalproex Sodium’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you follow Feingold Diet and take the medicine. 10 of them are worth acting on rather than waiting out — marked below.

  • Mania or an unusually elevated mood Worth acting on
  • Hearing loss Worth acting on
  • Bone thinning Worth acting on
  • Pain or burning when passing urine Worth acting on
  • Memory problems Worth acting on
  • Low sodium Worth acting on
  • Unsteadiness Worth acting on
  • A slow heartbeat Worth acting on
  • Seizures Worth acting on mentioned in 5.7% of FDA reports for Divalproex Sodium
  • Hallucinations Worth acting on

Showing the 10 most notable of 72 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Divalproex Sodium. Read the label on DailyMed › Where a percentage is shown, it is the share of 46,266 voluntary FDA FAERS reports for Divalproex Sodium that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Feingold Diet’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Feingold Diet side to compare — that is a limit of the record, not a statement that Feingold Diet has no side effects.

From our Q&A

Questions About Feingold Diet or Divalproex Sodium

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Feingold Diet or Divalproex Sodium, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Divalproex Sodium

This page covers Feingold Diet only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Divalproex Sodium page lists 134 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Kava (major).

By severity: 7 major · 110 moderate · 17 minor.

Open the Divalproex Sodium interaction page

How much people look this up

Where Feingold Diet and Divalproex Sodium Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Feingold Diet
Steady interest

#1,089 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Divalproex Sodium
Steady interest

#1,652 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Feingold Diet reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Feingold Diet and Divalproex Sodium records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Eating pattern

About Feingold Diet

What is Feingold Diet?

  • Hyperactivity (ADHD) in children
  • Behavioral problems in kids
  • Attention and focus concerns
  • Childhood sleep and mood issues

The Feingold Diet is an elimination eating plan that removes certain artificial food colors, flavors, sweeteners, preservatives, and some natural salicylate-containing foods, mainly to reduce hyperactivity in children. Scientific evidence is mixed and limited, though a small number of children may be sensitive to specific food additives. If you try it, work with a pediatrician or registered dietitian so your child still gets balanced nutrition.

Elimination diet / structured eating plan

An interaction check asks whether these two react with each other — it does not ask whether Feingold Diet is a good idea for someone in your situation. Here is what our Feingold Diet record says about it on its own.

Feingold Diet: dosing

There is no pill or standardized "dose" for the Feingold Diet — it is a pattern of eating. It is typically done in phases: a stricter starting period that removes targeted additives and salicylate-rich foods, followed by gradual reintroduction to identify specific triggers.Because the diet can be complex and restrictive, it is best to follow program guidance and work with a registered dietitian or pediatrician to make sure your child's overall diet stays balanced.

From our Feingold Diet monograph — the full record covers uses, side effects and every documented interaction.

Read the full Feingold Diet monograph & all interactions
Medication

About Valproic Acid

What Is Valproic Acid Used For?

Brand name: Depakote

Valproic acid capsules (brands Valproic and Valproic Acid) and valproic acid oral solution (brand Valproic Acid) are both used to treat epilepsy. Specifically, they are approved for complex partial seizures (either alone or with other seizure types) as monotherapy or add-on therapy, and for simple and complex absence seizures as sole therapy or add-on therapy.

Both forms are intended for adults and pediatric patients. Always follow your prescriber's guidance on which product and regimen is right for you.

Most-Reported Side Effects for Divalproex Sodium

From FAERS, the FDA’s public side-effect reporting system (46,266 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Seizure 2,620 reports
Weight increased 2,168 reports
Nausea 2,109 reports
Fatigue 1,963 reports
Somnolence 1,901 reports
See full Valproic Acid drug information
Keep checking

Other Drugs & Feingold Diet

Browse every other medication we’ve checked against Feingold Diet — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Feingold Diet References

The 2 references that drive our Feingold Diet monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Conners CK, Goyette CH, Southwick DA, et al. Food additives and hyperkinesis: a controlled double-blind experiment. Pediatrics 1976;58:154-66. DOI
  2. Harley JP, Ray RS, Tomasi L, et al. Hyperkinesis and food additives: testing the Feingold hypothesis. Pediatrics 1978;61:818-28. DOI

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Following Feingold Diet While Taking Divalproex Sodium: Common Questions

Is it safe to follow Feingold Diet while taking Divalproex Sodium?
We do not list a known interaction between Feingold Diet and Divalproex Sodium. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Divalproex Sodium interact with any supplements?
Yes. Divalproex Sodium has documented interactions with 134 supplements in our database — Feingold Diet is not one of them. The Divalproex Sodium interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Divalproex Sodium and Feingold Diet?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.