Drug & supplement interaction

Fo-ti + Ipratropium, Albuterol

Ipratropium, Albuterol brand names: Combivent, Combivent Respimat.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 13, 2026

The bottom line No known interaction

We found no known interaction between Fo-ti and Ipratropium, Albuterol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Fo-ti and Ipratropium, Albuterol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ipratropium, Albuterol and Fo-ti in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Fo-ti safety at a glance

Fo-ti overall Use caution It has been linked to cases of liver injury and should be used carefully and under professional guidance.

Pregnancy Possibly Unsafe When used orally. Fo-ti contains anthraquinone constituents, which can exert a stimulant laxative effect. Bulk-forming or emollient laxatives are preferred in p... Read the full pregnancy detail

Breastfeeding Possibly Unsafe When used orally. Anthraquinone constituents can cross into breast milk and might cause loose stools in some breast-fed infants. Fo-ti has also been linked to s... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ipratropium, Albuterol and Fo-ti? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

How we checked

Why No Interaction Is Listed for Ipratropium, Albuterol

Interactions in our licensed database are recorded against drug classes, not just single drug names. Ipratropium, Albuterol is filed under 2 classifications — beta-adrenergic agonists, anticholinergic drugs. Fo-ti has documented interactions with 17 drug classes — the most serious being anticoagulant/antiplatelet drugs (moderate), antidiabetes drugs (moderate) and contraceptive drugs (moderate) — and none of Ipratropium, Albuterol’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Fo-ti Does Interact With Other Medications

Fo-ti has 1,257 moderate known drug interactions in our database — Ipratropium, Albuterol isn’t one of them. If you take anything else, check it against the full list below.

Moderate 1,257 No known interaction 1,573 (incl. Ipratropium, Albuterol)

Taking anything else?

Check Another of Your Medications Against Fo-ti

Covers the 2,830 medications we’ve checked against Fo-ti. Pick one to open its full report.

What to actually watch for

What Fo-ti Itself Has Been Linked To

This is not an interaction — nothing below involves Ipratropium, Albuterol. It is the side-effect record for Fo-ti on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Fo-ti, this list is the first place to look. 2 entries are worth acting on rather than waiting out — marked below.

Yellowing of the skin or eyes / A low platelet count Worth acting on Additional detail
“Orally, cases of liver damage due to both processed and unprocessed fo-ti have been well documented in the medical literature..

In a systematic review, around 450 cases of hepatitis associated with fo-ti were identified. These cases occurred in patients 5-78 years of age. Liver damage occurred at a wide range of doses, formulations, and durations of intake.”

Fo-ti · Natural Medicines adverse-effect record, reported in cirrhosis.
6 sources cited

7626. Park GJ, Mann SP, Ngu MC. Acute hepatitis induced by Shou-Wu-Pian, a herbal product derived from Polygonum multiflorum. J Gastroenterol Hepatol 2001;16:115-7.

7627. But PP, Tomlinson B, Lee KL. Hepatitis related to the Chinese medicine Shou-wu-pian manufactured from Polygonum multiflorum. Vet Hum Toxicol 1996;38:280-2.

14327. UK Medicines and Healthcare Products Regulatory Agency. Polygonum multiflorum and liver reactions. April 2006. Available at: www.mhra.gov.uk/home/idcplg?IdcService= SS_GET_PAGE&useSecondary=true&ssDocName= CON2023590&ssTargetNodeId= 833 (Accessed 10 May 2

14339. Panis B, Wong DR, Hooymans PM, De Smet PA, Rosias PP. Recurrent toxic hepatitis in a Caucasian girl related to the use of Shou-Wu-Pian, a Chinese herbal preparation. J Pediatr Gastroenterol Nutr 2005;41:256-8. PubMed

14347. Mazzanti G, Battinelli L, Daniele C, et al. New case of acute hepatitis following the consumption of Shou Wu Pian, a Chinese herbal product derived from Polygonum multiflorum. Ann Intern Med 2004;140:E589-90.

14482. Cardenas A, Restrepo JC, Sierra F, Correa G. Acute hepatitis due to shen-min: a herbal product derived from Polygonum multiflorum. J Clin Gastroenterol 2006;40:629-32. PubMed
Liver problems Worth acting on Additional detail

“Orally, fo-ti may be unsafe.

Most Common Adverse Effects:

Orally: Abdominal pain, diarrhea, nausea, and vomiting with use of unprocessed fo-ti.

Serious Adverse Effects (Rare):

Orally: Hepatotoxicity with processed or unprocessed fo-ti.”

Fo-ti · Natural Medicines adverse-effect record, reported in diarrhea.
Reduced appetite / Fever / Tiredness / A skin rash Additional detail

Recorded for Fo-ti in the same Natural Medicines adverse-effect record shown under Yellowing of the skin or eyes / A low platelet count above.
Stomach pain Additional detail

Recorded for Fo-ti in the same Natural Medicines adverse-effect record shown under Liver problems above.
Diarrhea / Vomiting Additional detail
“Orally, unprocessed fo-ti may cause diarrhea, abdominal pain, nausea, and vomiting (12,50733).”

Fo-ti · Natural Medicines adverse-effect record, reported in diarrhea.
2 sources cited

12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

50733. McGuffin, M., Hobbs, C., Upton, R., and Goldberg, A. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC;1997.

Showing the 10 most notable of 11 recorded effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

Everything above comes from the Natural Medicines adverse-effect record for Fo-ti — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Ipratropium, Albuterol’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Ipratropium, Albuterol column appears here.

Special populations

Fo-ti in Pregnancy & Breastfeeding

Pregnancy Possibly Unsafe

When used orally. Fo-ti contains anthraquinone constituents, which can exert a stimulant laxative effect. Bulk-forming or emollient laxatives are preferred in pregnancy. Fo-ti has also been linked to several cases of liver damage. There is insufficient reliable information available about the safety of fo-ti when used topically during pregnancy.

Lactation Possibly Unsafe

When used orally. Anthraquinone constituents can cross into breast milk and might cause loose stools in some breast-fed infants. Fo-ti has also been linked to several cases of liver damage. There is insufficient reliable information available about the safety of fo-ti when used topically during lactation.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Ipratropium, Albuterol

This page covers Fo-ti only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ipratropium, Albuterol page lists 45 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Henbane (major), Scopolia (major), Angel's Trumpet (moderate), Bacopa (moderate) and Belladonna (moderate).

By severity: 2 major · 41 moderate · 2 minor.

From our pharmacist’s overview on the Ipratropium, Albuterol page

“Combivent (ipratropium with albuterol) is an inhaler that opens the airways two ways at once, by blocking acetylcholine and stimulating beta receptors, and both mechanisms give supplements a route to pile on. Its list of 45 interacting ingredients warrants real attention, chiefly because two rate major: henbane and scopolia, herbs whos…”

Reviewed by 2 · Jul 18, 2026

Open the Ipratropium, Albuterol interaction page

One more smart check

Taking Fo-ti as Part of a Dietary Supplement Product? Check It for Interactions

We hold 976 real supplement products containing Fo-ti, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Fo-ti. Even though Fo-ti itself has no known interaction with Ipratropium, Albuterol, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Fo-ti and Ipratropium, Albuterol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Fo-ti

Top 25%

#217 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Ipratropium, Albuterol

Steady interest

#2,704 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Fo-ti reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Fo-ti and Ipratropium, Albuterol records this page draws on were last updated July 11, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Fo-ti

What is Fo-ti?

Anti-aging and longevity
Hair graying and hair loss
General tonic for vitality
Constipation
High cholesterol

Fo-ti (He Shou Wu) is a root used in traditional Chinese medicine, often promoted for healthy aging and hair. High-quality human evidence for these benefits is limited, and processed Fo-ti has been linked to reports of liver injury, so caution and professional guidance are important.

Reynoutria multiflora · Polygonaceae · Root (often prepared/processed) · Capsules, tablets, dried root, tea, tinctures, powders

An interaction check asks whether these two react with each other — it does not ask whether Fo-ti is a good idea for someone in your situation. Here is what our Fo-ti record says about it on its own.

Fo-ti: dosing

There is no well-established, standardized dose of Fo-ti, and products vary widely in strength and preparation (raw versus prepared root). Because of this and the liver concerns, it is best not to guess at an amount on your own.If you choose to use it, follow the directions on the product label and do not exceed them.

From our Fo-ti monograph — the full record covers uses, side effects and every documented interaction.

Read the full Fo-ti monograph & all interactions

Keep checking

Other Drugs & Fo-ti

Browse every other medication we’ve checked against Fo-ti — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

1,257Moderate

0Minor

1,572No known interaction

1,257 Moderate 1,572 No interaction

Moderate

1,257 interactions

Showing 60 of 1,257 moderate interactions — see all 1,257 on the Fo-ti page.

No interaction 1,572 drugs checked — show the list

We also checked Fo-ti against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 1,572 medications checked with no known interaction — see the full Fo-ti list.

See the full Fo-ti interactions page

See every supplement checked against Ipratropium, Albuterol, ranked by severity

Evidence & sources

Fo-ti References

The 28 references that drive our Fo-ti monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
Park GJ, Mann SP, Ngu MC. Acute hepatitis induced by Shou-Wu-Pian, a herbal product derived from Polygonum multiflorum. J Gastroenterol Hepatol 2001;16:115-7.
But PP, Tomlinson B, Lee KL. Hepatitis related to the Chinese medicine Shou-wu-pian manufactured from Polygonum multiflorum. Vet Hum Toxicol 1996;38:280-2.
Oerter Klein KO, Janfaza M, Wong JA, Chang RJ. Estrogen bioactivity in Fo-Ti and other herbs used for their estrogen-like effects as determined by a recombinant cell bioassay. J Clin Endocrinol Metab 2003;88:4077-9.. PubMed
Unger M, Frank A. Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction. Rapid Commun Mass Spectrom 2004;1 PubMed
UK Medicines and Healthcare Products Regulatory Agency. Polygonum multiflorum and liver reactions. April 2006. Available at: www.mhra.gov.uk/home/idcplg?IdcService= SS_GET_PAGE&useSecondary=true&ssDocName= CON2023590&ssTargetNodeId= 833 (Accessed 10 May 2
Panis B, Wong DR, Hooymans PM, De Smet PA, Rosias PP. Recurrent toxic hepatitis in a Caucasian girl related to the use of Shou-Wu-Pian, a Chinese herbal preparation. J Pediatr Gastroenterol Nutr 2005;41:256-8. PubMed
Mazzanti G, Battinelli L, Daniele C, et al. New case of acute hepatitis following the consumption of Shou Wu Pian, a Chinese herbal product derived from Polygonum multiflorum. Ann Intern Med 2004;140:E589-90.
Cardenas A, Restrepo JC, Sierra F, Correa G. Acute hepatitis due to shen-min: a herbal product derived from Polygonum multiflorum. J Clin Gastroenterol 2006;40:629-32. PubMed
Zhang CZ, Wang SX, Zhang Y, et al. In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms. J Ethnopharmacol 2005;98:295-300. PubMed
Laird AR, Ramchandani N, deGoma EM, et al. Acute hepatitis associated with the use of an herbal supplement (Polygonum multiflorum) mimicking iron-overload syndrome. J Clin Gastroenterol 2008;42:861-2. PubMed
Jung KA, Min HJ, Yoo SS, et al. Drug-Induced Liver Injury: Twenty Five Cases of Acute Hepatitis Following Ingestion of Polygonum multiflorum Thunb. Gut Liver 2011;5(4):493-9. PubMed
Kang, S. C., Lee, C. M., Choi, H., Lee, J. H., Oh, J. S., Kwak, J. H., and Zee, O. P. Evaluation of oriental medicinal herbs for estrogenic and antiproliferative activities. Phytother Res 2006;20(11):1017-1019. PubMed
Yuen, M. F., Tam, S., Fung, J., Wong, D. K., Wong, B. C., and Lai, C. L. Traditional Chinese medicine causing hepatotoxicity in patients with chronic hepatitis B infection: a 1-year prospective study. Aliment.Pharmacol.Ther 10-15-2006;24(8):1179-1186. PubMed
Zhang, L., Yang, X., Sun, Z., and Qu, Y. [Retrospective study of adverse events of Polygonum multiflorum and risk control]. Zhongguo Zhong.Yao Za Zhi. 2009;34(13):1724-1729.
Bae, S. H., Kim, D. H., Bae, Y. S., Lee, K. J., Kim, D. W., Yoon, J. B., Hong, J. H., and Kim, S. H. [Toxic hepatitis associated with Polygoni multiflori]. Korean J.Hepatol. 2010;16(2):182-186. PubMed
Furukawa, M., Kasajima, S., Nakamura, Y., Shouzushima, M., Nagatani, N., Takinishi, A., Taguchi, A., Fujita, M., Niimi, A., Misaka, R., and Nagahara, H. Toxic hepatitis induced by show-wu-pian, a Chinese herbal preparation. Intern.Med. 2010;49(15):1537-1 PubMed
McGuffin, M., Hobbs, C., Upton, R., and Goldberg, A. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC;1997.
Dong H, Slain D, Cheng J, Ma W, Liang W. Eighteen cases of liver injury following ingestion of Polygonum multiflorum. Complement Ther Med 2014;22(1):70-4. PubMed
Lei X, Chen J, Ren J, et al. Liver damage associated with Polygonum multiflorum Thunb.: a systematic review of case reports and case series. Evid Based Complement Alternat Med 2015;2015:459749.
Ma KF, Zhang XG, Jia HY. CYP1A2 polymorphism in Chinese patients with acute liver injury induced by Polygonum multiflorum. Genet Mol Res 2014;13(3):5637-43. PubMed
Zhang Y, Ding T, Diao T, Deng M, Chen S. Effects of Polygonum multiflorum on the activity of cytochrome P450 isoforms in rats. Pharmazie 2015;70(1):47-54. DOI
Yu J, Xie J, Mao XJ, et al. Comparison of laxative and antioxidant activities of raw, processed and fermented Polygoni multiflori radix. Chin J Nat Med 2012;10(1):63-7. DOI
Shao YL, Ma CM, Wu JM, Guo FC, Zhang SC. Concurrent severe hepatotoxicity and agranulocytosis induced by Polygonum multiflorum: A case report. World J Clin Cases 2022;10(27):9921-9928.
Xing Y, Yu Q, Zhou L, et al. Cytochrome P450-mediated herb-drug interaction (HDI) of Polygonum multiflorum Thunb. based on pharmacokinetic studies and in vitro inhibition assays. Phytomedicine 2023;112:154710. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Related: nutrient depletion

Ipratropium, Albuterol Is Linked to Lower Levels of 2 Nutrients

Natural Medicines records Ipratropium, Albuterol as a medicine that can lower these. This is not an interaction with Fo-ti — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:

Read the full Ipratropium, Albuterol nutrient depletion report ›

Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.

Pharmacist Counseling Corner

Taking Fo-ti and Ipratropium, Albuterol Together: Common Questions

Is it safe to take Fo-ti with Ipratropium, Albuterol?

We do not list a known interaction between Fo-ti and Ipratropium, Albuterol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

How was the Fo-ti and Ipratropium, Albuterol combination checked?

Interactions in our licensed database are recorded against drug classes. Ipratropium, Albuterol is filed under 2 classifications, and Fo-ti has documented interactions with 17 drug classes — none of Ipratropium, Albuterol's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.

Does Fo-ti interact with any other medications?

Yes. Fo-ti has 1,257 documented drug interactions in our database — Ipratropium, Albuterol is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Does Ipratropium, Albuterol interact with any supplements?

Yes. Ipratropium, Albuterol has documented interactions with 45 supplements in our database — Fo-ti is not one of them. The Ipratropium, Albuterol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Fo-ti monograph Uses, safety profile, and every drug interaction in one place Ipratropium, Albuterol supplement interactions Every supplement checked against Ipratropium, Albuterol, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 28 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Ipratropium, Albuterol and Fo-ti?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.