Drug & supplement interaction

German Ipecac + Edaravone

Edaravone brand names: Radicava, Radicava ORS.

No Known Interaction
The bottom line No known interaction

We found no known interaction between German Ipecac and Edaravone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Edaravone states a food rule worth keeping to.

Know someone taking this? Share
Interaction report

German Ipecac and Edaravone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Edaravone and German Ipecac in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for German Ipecac at all — not against Edaravone, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

German Ipecac safety at a glance

German Ipecac overall Use caution Ipecac-type preparations can cause forceful vomiting and have a narrow margin of safety.
Pregnancy Possibly Unsafe When used orally; avoid using. Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Edaravone and German Ipecac? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What German Ipecac Itself Has Been Linked To

This is not an interaction — nothing below involves Edaravone. It is the side-effect record for German Ipecac on its own, from the licensed Natural Medicines monograph. If something new turns up after you add German Ipecac, this list is the first place to look.

  • Vomiting Additional detail

    “Orally, high doses of German ipecac may cause vomiting, apnea, and cardiac arrest. Seed extracts may cause advancing paralysis of the central nervous system (18).”

    German Ipecac · Natural Medicines adverse-effect record, reported in cardiac arrest.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Everything above comes from the Natural Medicines adverse-effect record for German Ipecac — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Edaravone’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Edaravone column appears here.

Special populations

German Ipecac in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Edaravone Products Have a Food Rule — German Ipecac Should Not Break It

At least one FDA label for a product containing Edaravone says to take it on an empty stomach. Most supplements — German Ipecac included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Edaravone on its own and move German Ipecac to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Edaravone products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

RADICAVA ORS should be taken in the morning on an empty stomach after overnight fasting.

From the Dosage and Administration section of the FDA label we read for Edaravone — where that label names a specific product, the instruction is that product's. See the Edaravone drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Edaravone

This page covers German Ipecac only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Edaravone page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

Open the Edaravone interaction page

How much people look this up

Where German Ipecac and Edaravone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement German Ipecac
Top half

#496 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Edaravone
Top half

#826 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every German Ipecac reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The German Ipecac and Edaravone records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About German Ipecac

What is German Ipecac?

  • To cause vomiting (emetic)
  • Loosening chest congestion
  • Nausea (in homeopathic dilutions)
  • Cough and bronchial complaints

"German Ipecac" is an uncommon name, and the source plant is not clearly established, so be very cautious about any product sold under this name. True ipecac is a powerful emetic that is no longer recommended for treating poisoning and can be dangerous if misused. Talk to a pharmacist or doctor before using any product labeled as ipecac.

Root and rhizome · Tincture, syrup, homeopathic preparations, dried root

An interaction check asks whether these two react with each other — it does not ask whether German Ipecac is a good idea for someone in your situation. Here is what our German Ipecac record says about it on its own.

German Ipecac: dosing

There is no established, standardized dose for a product called "German Ipecac," and reliable dosing information for this specific name does not exist. Never increase the dose or repeat it on your own. Keep all such products out of reach of children.

From our German Ipecac monograph — the full record covers uses, side effects and every documented interaction.

Read the full German Ipecac monograph & all interactions
Medication

About Edaravone Oral

What Is Edaravone Oral Used For?

Brand names: Radicava, Radicava ORS

  • Edaravone is used to treat amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease; a condition in which the nerves that control muscle movement slowly die, causing the muscles to shrink and weaken). Edaravone is in a class of medications called antioxidants. It may work to slow the nerve damage associated with the worsening of ALS symptoms.

Most-Reported Side Effects for Edaravone

From FAERS, the FDA’s public side-effect reporting system (1,540 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Cerebral infarction 97 reports
Amyotrophic lateral sclerosis 78 reports
Disease progression 72 reports
Dyspnea 49 reports
Muscular weakness 45 reports
See full Edaravone Oral drug information
Keep checking

Other Drugs & German Ipecac

Browse every other medication we’ve checked against German Ipecac — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

German Ipecac References

The 1 references that drive our German Ipecac monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking German Ipecac and Edaravone Together: Common Questions

Is it safe to take German Ipecac with Edaravone?
We do not list a known interaction between German Ipecac and Edaravone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take German Ipecac and Edaravone at the same time of day?
At least one FDA label for a product containing Edaravone says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Edaravone on its own and move German Ipecac to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
Does Edaravone interact with any supplements?
Yes. Edaravone has documented interactions with 17 supplements in our database — German Ipecac is not one of them. The Edaravone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Edaravone and German Ipecac?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.