Drug & supplement interaction

Germander + Clemastine

Clemastine brand name: Tavist Allergy.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Germander and Clemastine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Germander and Clemastine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Clemastine and Germander in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Germander at all — not against Clemastine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Germander safety at a glance

Germander overall Avoid Germander has been linked to serious, sometimes fatal liver injury and should be avoided.
Pregnancy Likely Unsafe When used orally. Read the full pregnancy detail
Breastfeeding Likely Unsafe When used orally. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Clemastine and Germander? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Germander Itself Has Been Linked To

This is not an interaction — nothing below involves Clemastine. It is the side-effect record for Germander on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Germander, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Liver problems Worth acting on Additional detail

    “Orally, germander has been associated with hepatitis, liver cell necrosis, and death.”

    Germander · Natural Medicines adverse-effect record, reported in hepatitis.

    5 sources cited
    1. 271. Bruneton J. Pharmacognosy, Phytochemistry, Medicinal Plants. Paris: Lavoisier Publishing, 1995. DOI
    2. 3741. Larrey D, Vial T, Pauwels A, et al. Hepatitis after germander (Teucrium chamaedrys) administration: another instance of herbal medicine hepatotoxicity. Ann Intern Med 1992;117:129-32.
    3. 3742. Pauwels A, Thierman-Duffaud D, Azanowsky JM, et al. [Acute hepatitis caused by wild germander. Hepatotoxicity of herbal remedies. Two cases]. Gastroenterol Clin Biol 1992;16:92-5.
    4. 3743. Castot A, Djezzar S, Deleau N, et al. [Pharmacovigilance off the beaten track: herbal surveillance or pharmacovigilance of medicinal plants]. Therapie 1997;52:97-103.
    5. 3744. Mostefa-Kara N, Pauwels A, Pines E, et al. Fatal hepatitis after herbal tea. Lancet 1992;340:674. DOI

Everything above comes from the Natural Medicines adverse-effect record for Germander — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Clemastine’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Clemastine column appears here.

Special populations

Germander in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Unsafe

When used orally.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Germander or Clemastine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Germander or Clemastine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Clemastine

This page covers Germander only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Clemastine page lists 72 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Henbane (major), Scopolia (major), Alfalfa (moderate) and Angel's Trumpet (moderate).

By severity: 3 major · 57 moderate · 12 minor.

From our pharmacist’s overview on the Clemastine page

“Clemastine (Tavist Allergy) is an older, sedating antihistamine that already dries the mouth, blurs vision, and slows the gut, and that is exactly why this list earns real caution rather than a quick skim. Thirty of the 72 supplements on file pile the same drying, sedating anticholinergic load on top, and two of the three major-rated e…”

Reviewed by 2 · Jul 18, 2026

Open the Clemastine interaction page

How much people look this up

Where Germander and Clemastine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Germander
Steady interest

#897 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Clemastine
Steady interest

#2,318 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Germander reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Germander and Clemastine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Germander

What is Germander?

  • Weight loss aids
  • Digestive complaints
  • Appetite stimulation
  • Gout and arthritis (traditional)
  • Fever and infections (traditional)

Germander is a traditional herb that was once used for weight loss and digestion, but it has been linked to serious and sometimes fatal liver damage. Because of these well-documented liver risks, germander has been banned or restricted in several countries, and we strongly advise against using it.

Teucrium chamaedrys · Lamiaceae · Above-ground parts (leaves and flowering tops) · Tea, capsules, tinctures, dried herb

An interaction check asks whether these two react with each other — it does not ask whether Germander is a good idea for someone in your situation. Here is what our Germander record says about it on its own.

Germander: dosing

There is no safe or established dose for germander. A safer, evidence-based option is almost always available.

From our Germander monograph — the full record covers uses, side effects and every documented interaction.

Read the full Germander monograph & all interactions
Medication

About Clemastine

What Is Clemastine Used For?

Brand name: Tavist Allergy

Clemastine treats symptoms of allergic rhinitis (hay fever and similar nasal allergies) — including sneezing, runny nose, itching, and watery eyes. The oral solution (Clemastine Fumarate syrup) is indicated for adults and children aged 6 through 12 years. The tablets (Clemastine Fumarate and Clemsza) are indicated for adults.

Clemastine also treats mild, uncomplicated allergic skin reactions — specifically urticaria (hives) and angioedema (swelling under the skin) — at the appropriate dosage level, in both the oral solution and tablet forms.

See full Clemastine drug information
Keep checking

Other Drugs & Germander

Browse every other medication we’ve checked against Germander — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Germander References

The 5 references that drive our Germander monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Bruneton J. Pharmacognosy, Phytochemistry, Medicinal Plants. Paris: Lavoisier Publishing, 1995. DOI
  2. Larrey D, Vial T, Pauwels A, et al. Hepatitis after germander (Teucrium chamaedrys) administration: another instance of herbal medicine hepatotoxicity. Ann Intern Med 1992;117:129-32.
  3. Pauwels A, Thierman-Duffaud D, Azanowsky JM, et al. [Acute hepatitis caused by wild germander. Hepatotoxicity of herbal remedies. Two cases]. Gastroenterol Clin Biol 1992;16:92-5.
  4. Castot A, Djezzar S, Deleau N, et al. [Pharmacovigilance off the beaten track: herbal surveillance or pharmacovigilance of medicinal plants]. Therapie 1997;52:97-103.
  5. Mostefa-Kara N, Pauwels A, Pines E, et al. Fatal hepatitis after herbal tea. Lancet 1992;340:674. DOI

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Germander and Clemastine Together: Common Questions

Is it safe to take Germander with Clemastine?
We do not list a known interaction between Germander and Clemastine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Clemastine interact with any supplements?
Yes. Clemastine has documented interactions with 72 supplements in our database — Germander is not one of them. The Clemastine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Clemastine and Germander?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.