Medication interaction hub

What Supplements Interact with Clemastine?

Clemastine brand name: Tavist Allergy. Every interaction below applies to the brands too.

72 Interactions 3 Major 57 Moderate 12 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Clemastine? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Clemastine against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Clemastine (Tavist Allergy) is an older, sedating antihistamine that already dries the mouth, blurs vision, and slows the gut, and that is exactly why this list earns real caution rather than a quick skim. Thirty of the 72 supplements on file pile the same drying, sedating anticholinergic load on top, and two of the three major-rated entries, henbane and scopolia, contain atropine-like alkaloids strong enough to make that combination genuinely risky. The third major, activated charcoal, works the opposite way, binding the drug in the gut so less of it ever reaches you.

The rest of the list runs milder. Twenty ingredients can add sun sensitivity, seventeen can change how oral doses absorb (bulky products like glucomannan and coffee charcoal belong well apart from any pill), and six may make seizures slightly easier to trigger. Fifty-seven entries rate moderate and twelve minor, but henbane, scopolia, and charcoal are where the real danger sits.

— , Clinical Pharmacist · July 18, 2026

Major 3 Moderate 57 Minor 12 No known interaction 1,380

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Clemastine: Top Interactions at a Glance

The Clemastine supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 72 interacting ingredients — plus 1,380 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Clemastine Combinations Today

The Clemastine + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Chlorella + Clemastinei

Theoretically, chlorella might have additive effects with photosensitizing drugs.

Read the full interaction Moderate Likelihood Probable Belladonna + Clemastinei

Belladonna may increase the risk of adverse effects when used concomitantly with anticholinergic drugs.

Read the full interaction Moderate Likelihood Possible Methylene Blue + Clemastinei

Concomitant use may increase anticholinergic effects and adverse effects.

Read the full interaction Moderate Likelihood Possible Purple Nut Sedge + Clemastinei

In vitro, purple nut sedge dose-dependently inhibits acetylcholinesterase (AChE).

Read the full interaction Major Likelihood Probable Activated Charcoal + Clemastinei

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.

Read the full interaction Major Likelihood Probable Henbane + Clemastinei

Concomitant use of henbane can have additive anticholinergic effects and adverse effects with amantadine, antihistamines, atropine, belladonna alkaloids, hyoscy...

Read the full interaction
The complete list

Every Supplement Checked Against Clemastine

All 1,452 ingredients in our database, ranked by severity — 72 with a Clemastine interaction on file and 1,380 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Clemastine?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Chlorella with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, chlorella might have additive effects with photosensitizing drugs.

Full Chlorella + Clemastine answer

Can you take Belladonna with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Belladonna may increase the risk of adverse effects when used concomitantly with anticholinergic drugs.

Full Belladonna + Clemastine answer

Can you take Methylene Blue with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concomitant use may increase anticholinergic effects and adverse effects.

Full Methylene Blue + Clemastine answer

Can you take Purple Nut Sedge with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro, purple nut sedge dose-dependently inhibits acetylcholinesterase (AChE).

Full Purple Nut Sedge + Clemastine answer

Can you take Coffee Charcoal with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Coffee charcoal can reduce the absorption of orally administered drugs and should be separated from oral drug administration by at least two...

Full Coffee Charcoal + Clemastine answer

Can you take Datura Wrightii with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Datura wrightii contains atropine and scopolamine, as well as other tropane alkaloids with anticholinergic activity.

Full Datura Wrightii + Clemastine answer

Can you take European Mandrake with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use might increase absorption of some drugs because of inhibited gastrointestinal (GI) motility caused by European...

Full European Mandrake + Clemastine answer

Can you take Glucomannan with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, glucomannan may decrease absorption of drugs taken orally.

Full Glucomannan + Clemastine answer

Can you take Masterwort with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. The use of masterwort in conjunction with photosensitizing drugs is contraindicated due to the potential for additive photosensitizing effec...

Full Masterwort + Clemastine answer

Can you take Wild Carrot with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might result in increased photosensitivity.

Full Wild Carrot + Clemastine answer

Can you take Alfalfa with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.

Full Alfalfa + Clemastine answer

Can you take Angel's Trumpet with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concomitant use may increase anticholinergic effects and adverse effects.

Full Angel's Trumpet + Clemastine answer

Can you take Angelica Archangelica with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Angelica archangelica, whether ingested or applied to the skin, has the potential to induce photosensitivity reactions.

Full Angelica Archangelica + Clemastine answer

Can you take Arrach with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of arrach can increase risk of adverse effects, as unspecified Chenopodium species are associated with photos...

Full Arrach + Clemastine answer

Can you take Bacopa with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use might decrease the effectiveness of both agents.

Full Bacopa + Clemastine answer

Can you take Biofeedback with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. There is some concern that electroencephalogram (EEG) biofeedback might lower the seizure threshold in some patients.

Full Biofeedback + Clemastine answer

Can you take Bishop's Weed with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Bishop's weed constituents seem to cause photosensitivity.

Full Bishop's Weed + Clemastine answer

Can you take Boxwood with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from in vitro research suggests that boxwood extract can inhibit acetylcholinesterase activity.

Full Boxwood + Clemastine answer

Can you take Calamus with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use of anticholinergic drugs and calamus might decrease the effectiveness of the anticholinergic drug.

Full Calamus + Clemastine answer

Can you take Cilantro with Clemastine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from in vitro research suggests that coriandrin, a constituent of cilantro, has photosensitizing effects.

Full Cilantro + Clemastine answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Clemastine is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Clemastine, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Clemastine sits in 4 interaction categories. Open any one to see what the group means:

Anticholinergic Drugs 30 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

30 of the supplement ingredients on this page reach Clemastine through this category.

Photosensitizing Drugs 20 ingredients

Medications that make skin more sun-sensitive. Supplements with the same property can compound it.

20 of the supplement ingredients on this page reach Clemastine through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Clemastine through this category.

Seizure Threshold Lowering Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Clemastine through this category.

About Clemastine

Clemastine is an antihistamine used to relieve allergy and hay fever symptoms like sneezing, runny nose, and itchy eyes.

Generic name: Clemastine  ·  Brand name: Tavist Allergy.

See the full Clemastine drug information
Check a real product

Take a Supplement Product? Check the Whole Bottle Against Clemastine

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Clemastine.

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Pharmacist Counseling Corner

Clemastine & Supplements: Common Questions

What supplements interact with Clemastine?
More than you might expect — 72 in total, though they are far from equal: 3 are rated major, 57 moderate, and 12 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: Activated Charcoal, Henbane, Scopolia.
Which Clemastine supplement interactions are the most serious?
Focus on the major group: Activated Charcoal, Henbane and Scopolia. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Clemastine?
Usually yes — most people on Clemastine can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Tavist Allergy have the same supplement interactions as Clemastine?
Yes — Tavist Allergy all contain Clemastine, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Clemastine and my other medications?
This page covers Clemastine against supplements and herbal ingredients. Checking Clemastine against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Clemastine drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.