Drug & supplement interaction

Goa Powder + Acetaminophen, Aspirin, Caffeine

Acetaminophen, Aspirin, Caffeine brand names: Excedrin Migraine, Excedrin, Excedrin Extra Strength.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Goa Powder and Acetaminophen, Aspirin, Caffeine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Goa Powder and Acetaminophen, Aspirin, Caffeine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Acetaminophen, Aspirin, Caffeine and Goa Powder in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Goa Powder at all — not against Acetaminophen, Aspirin, Caffeine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Goa Powder safety at a glance

Goa Powder overall Use caution It is a strong skin irritant meant only for external use and can be toxic if swallowed.
Pregnancy Avoid Safety has not been established, so avoid use during pregnancy.
Breastfeeding Avoid Safety has not been established, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Acetaminophen, Aspirin, Caffeine and Goa Powder? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Goa Powder Itself Has Been Linked To

This is not an interaction — nothing below involves Acetaminophen, Aspirin, Caffeine. It is the side-effect record for Goa Powder on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Goa Powder, this list is the first place to look.

  • Swelling Additional detail

    “Topically, application of goa powder can cause redness, swelling, pustules, and conjunctivitis (18).”

    Goa Powder · Natural Medicines adverse-effect record, reported in conjunctivitis.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  • Diarrhea / Vomiting Additional detail

    “Goa powder can cause vomiting and diarrhea when taken orally or absorbed through the skin (18).”

    Goa Powder · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Everything above comes from the Natural Medicines adverse-effect record for Goa Powder — expand a row for the licensed statement it rests on. We haven’t matched Acetaminophen, Aspirin, Caffeine to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Acetaminophen, Aspirin, Caffeine.

Everything else you take

See Every Supplement That Interacts With Acetaminophen, Aspirin, Caffeine

This page covers Goa Powder only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Acetaminophen, Aspirin, Caffeine page lists 371 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Danshen (major) and Ephedra (major).

By severity: 13 major · 312 moderate · 46 minor.

From our pharmacist’s overview on the Acetaminophen, Aspirin, Caffeine page

“Excedrin (acetaminophen, aspirin, and caffeine) packs three drugs into one tablet, which multiplies the ways supplements can collide with it, so treat this list with real care. Most entries involve the aspirin: hundreds of herbs add to its blood-thinning effect and raise bleeding risk, and even beer or wine earns a major rating for sto…”

Reviewed by 2 · Jul 18, 2026

Open the Acetaminophen, Aspirin, Caffeine interaction page

How much people look this up

Where Goa Powder and Acetaminophen, Aspirin, Caffeine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Goa Powder
Steady interest

#951 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Acetaminophen, Aspirin, Caffeine
Top 5%

#77 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Goa Powder reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Goa Powder and Acetaminophen, Aspirin, Caffeine records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Goa Powder

What is Goa Powder?

  • Psoriasis (topical)
  • Ringworm and other fungal skin infections
  • Scaly skin conditions
  • Eczema-like rashes

Goa powder (also called araroba) is a natural source of chrysarobin, a substance historically used on the skin for psoriasis and fungal infections. It is a harsh, irritating chemical that is mostly of historical interest today, and it should never be swallowed. If you are considering anything containing chrysarobin or anthralin, talk with a doctor or pharmacist first.

Andira araroba · Fabaceae · A yellow powder (chrysarobin) extracted from the wood and trunk cavities of the araroba tree · Topical ointments, pastes, and creams; historically a raw powder

An interaction check asks whether these two react with each other — it does not ask whether Goa Powder is a good idea for someone in your situation. Here is what our Goa Powder record says about it on its own.

Goa Powder: dosing

There is no established or standardized dose for Goa powder as a supplement. Historically it was mixed into ointments at concentrations chosen by a pharmacist or physician, and even then it had to be used carefully because of irritation and staining.If you encounter a product that contains chrysarobin or the related medicine anthralin, follow the product label exactly and do not apply more than directed. Because this is a potent and irritating substance, it is best to use it only under the guidance of a doctor or pharmacist.

From our Goa Powder monograph — the full record covers uses, side effects and every documented interaction.

Read the full Goa Powder monograph & all interactions
Medication

About Acetaminophen, Aspirin, Caffeine

Most-Reported Side Effects for Acetaminophen, Aspirin, Caffeine

From FAERS, the FDA’s public side-effect reporting system (442 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Expired product administered 81 reports
Nausea 30 reports
Underdose 25 reports
Drug ineffective for unapproved indication 24 reports
Dizziness 20 reports
Keep checking

Other Drugs & Goa Powder

Browse every other medication we’ve checked against Goa Powder — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Goa Powder against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Goa Powder list.

See the full Goa Powder interactions page
See every supplement checked against Acetaminophen, Aspirin, Caffeine, ranked by severity
Evidence & sources

Goa Powder References

The 1 references that drive our Goa Powder monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Goa Powder and Acetaminophen, Aspirin, Caffeine Together: Common Questions

Is it safe to take Goa Powder with Acetaminophen, Aspirin, Caffeine?
We do not list a known interaction between Goa Powder and Acetaminophen, Aspirin, Caffeine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Acetaminophen, Aspirin, Caffeine interact with any supplements?
Yes. Acetaminophen, Aspirin, Caffeine has documented interactions with 371 supplements in our database — Goa Powder is not one of them. The Acetaminophen, Aspirin, Caffeine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Goa Powder monograph Uses, safety profile, and every drug interaction in one place Acetaminophen, Aspirin, Caffeine supplement interactions Every supplement checked against Acetaminophen, Aspirin, Caffeine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Acetaminophen, Aspirin, Caffeine and Goa Powder?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.