Drug & supplement interaction

Herb Robert + Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate

Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate brand name: Xywav.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Herb Robert and Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate states a food rule worth keeping to.

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Interaction report

Herb Robert and Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate and Herb Robert in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Herb Robert at all — not against Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Herb Robert safety at a glance

Herb Robert overall Use caution Generally used in small amounts traditionally, but human safety data are very limited.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data exist for nursing mothers, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate and Herb Robert? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Herb Robert Itself Has Been Linked To

This is not an interaction — nothing below involves Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate. It is the side-effect record for Herb Robert on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Herb Robert, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • A severe skin reaction Worth acting on Additional detail

    “Topically, Herb Robert can cause contact dermatitis. There are at least two cases of known contact sensitization of elderly individuals to Herb Robert through gardening. One case resulted in an erythema multiforme-like eruption requiring treatment with steroids.”

    Herb Robert · Natural Medicines adverse-effect record, reported in dermatitis.

    2 sources cited
    1. 99144. Svendsen MT, Andersen KE, Thormann H, Paulsen E. Contact sensitization to Geranium robertianum L. in an amateur gardener. Contact Dermatitis. 2015;72(6):420-1.
    2. 99146. Badaoui A, Pecquet C, Fargeas C, Mahé E. Contact dermatitis caused by Geranium robertianum with erythema multiforme-like reaction. Contact Dermatitis. 2017;77(6):423-424.
  • A skin rash Additional detail

    “There is currently a limited amount of information on the adverse effects of Herb Robert. Topically, Herb Robert has been reported to cause allergic contact dermatitis.”

    Herb Robert · Natural Medicines adverse-effect record, reported in dermatitis.

    2 sources cited
    1. 99144. Svendsen MT, Andersen KE, Thormann H, Paulsen E. Contact sensitization to Geranium robertianum L. in an amateur gardener. Contact Dermatitis. 2015;72(6):420-1.
    2. 99146. Badaoui A, Pecquet C, Fargeas C, Mahé E. Contact dermatitis caused by Geranium robertianum with erythema multiforme-like reaction. Contact Dermatitis. 2017;77(6):423-424.

Everything above comes from the Natural Medicines adverse-effect record for Herb Robert — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate column appears here.

How to take them

Some Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate Products Have a Food Rule — Herb Robert Should Not Break It

At least one FDA label for a product containing Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate says to take it with food. If you take Herb Robert on an empty stomach out of habit, keep them separate — and take Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Important Administration Information • Administer XYWAV at least 2 hours after eating ( 2.4 ).

From the Dosage and Administration section of the FDA label we read for Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate — where that label names a specific product, the instruction is that product's. See the Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate

This page covers Herb Robert only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate page lists 23 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Biofeedback (moderate), Coffee Charcoal (moderate), Dendrobium (moderate) and European Mandrake (moderate).

By severity: 1 major · 13 moderate · 9 minor.

From our pharmacist’s overview on the Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate page

“Xywav combines calcium, magnesium, potassium, and sodium oxybates to treat cataplexy and daytime sleepiness in narcolepsy, and because each nightly dose is measured and timed with real precision, this list deserves genuine attention rather than a quick skim. The one major entry, activated charcoal, can bind the drug in the gut and shar…”

Reviewed by 2 · Jul 18, 2026

Open the Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate interaction page

How much people look this up

Where Herb Robert and Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Herb Robert
Steady interest

#1,122 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate
Top 25%

#686 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Herb Robert reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Herb Robert and Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Herb Robert

What is Herb Robert?

Herb Robert
  • Digestive upset
  • Wound and skin care
  • Sore throat and mouth irritation
  • Respiratory complaints
  • General 'detox' tonic

Herb Robert is a traditional European herb used for digestion, wounds, and minor inflammation, but there is very little human research to confirm it works for any condition. It is likely fine in small amounts as a tea for most healthy adults, but its safety has not been well studied. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Geranium robertianum · Geraniaceae · Above-ground parts (leaves, stems, and flowers) · Tea, tincture, dried herb, capsules, fresh poultice

An interaction check asks whether these two react with each other — it does not ask whether Herb Robert is a good idea for someone in your situation. Here is what our Herb Robert record says about it on its own.

Herb Robert: dosing

There is no established, standardized dose for Herb Robert. Traditional use involved brewing a small amount of the dried herb as a tea or applying crushed fresh leaves to the skin, but these amounts were not measured in a consistent, science-based way.If you choose to use a commercial product, follow the directions on the label and do not exceed the recommended amount.

From our Herb Robert monograph — the full record covers uses, side effects and every documented interaction.

Read the full Herb Robert monograph & all interactions
Medication

About Calcium, Magnesium, Potassium, and Sodium Oxybate

What Is Calcium, Magnesium, Potassium, and Sodium Oxybate Used For?

Brand name: Xywav

Xywav (calcium, magnesium, potassium, and sodium oxybate) is approved to treat two symptoms of narcolepsy — cataplexy (sudden muscle weakness triggered by emotion) and excessive daytime sleepiness (EDS) — in patients 7 years of age and older.

Xywav is also approved to treat idiopathic hypersomnia (IH) — a sleep disorder that causes excessive sleepiness even after long periods of sleep — in adults.

See full Calcium, Magnesium, Potassium, and Sodium Oxybate drug information
Keep checking

Other Drugs & Herb Robert

Browse every other medication we’ve checked against Herb Robert — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Herb Robert References

The 3 references that drive our Herb Robert monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Svendsen MT, Andersen KE, Thormann H, Paulsen E. Contact sensitization to Geranium robertianum L. in an amateur gardener. Contact Dermatitis. 2015;72(6):420-1.
  2. Panahi Y, Akhavan A, Sahebkar A, et al. Investigation of the effectiveness of Syzygium aromaticum, Lavandula angustifolia and Geranium robertianum essential oils in the treatment of acute external otitis: a comparative trial with ciprofloxacin. J Microbi PubMed
  3. Badaoui A, Pecquet C, Fargeas C, Mahé E. Contact dermatitis caused by Geranium robertianum with erythema multiforme-like reaction. Contact Dermatitis. 2017;77(6):423-424.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Herb Robert and Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate Together: Common Questions

Is it safe to take Herb Robert with Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate?
We do not list a known interaction between Herb Robert and Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Herb Robert and Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate at the same time of day?
At least one FDA label for a product containing Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate says to take it with food. If you take Herb Robert on an empty stomach out of habit, keep them separate and take Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate interact with any supplements?
Yes. Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate has documented interactions with 23 supplements in our database — Herb Robert is not one of them. The Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate and Herb Robert?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.