Drug & supplement interaction

Hollyhock + Conjugated Estrogens, Methyltestosterone

Conjugated Estrogens, Methyltestosterone brand name: Premarin with Methyltestosterone.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Hollyhock and Conjugated Estrogens, Methyltestosterone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Hollyhock and Conjugated Estrogens, Methyltestosterone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Conjugated Estrogens, Methyltestosterone and Hollyhock in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Hollyhock safety at a glance

Hollyhock overall Use caution Generally considered gentle, but human safety data are limited.
Pregnancy Avoid Not enough safety information, so it is best avoided.
Breastfeeding Avoid No reliable safety data during breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Conjugated Estrogens, Methyltestosterone and Hollyhock? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Conjugated Estrogens, Methyltestosterone

Interactions in our licensed database are recorded against drug classes, not just single drug names. Conjugated Estrogens, Methyltestosterone is filed under 9 classifications — including testosterone, androgens, ethinyl estradiol. Hollyhock has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Conjugated Estrogens, Methyltestosterone’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Hollyhock Does Interact With Other Medications

Hollyhock has 86 moderate known drug interactions in our database — Conjugated Estrogens, Methyltestosterone isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Hollyhock

Covers the 2,830 medications we’ve checked against Hollyhock. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Conjugated Estrogens, Methyltestosterone

This page covers Hollyhock only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Conjugated Estrogens, Methyltestosterone page lists 226 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).

By severity: 6 major · 184 moderate · 36 minor.

From our pharmacist’s overview on the Conjugated Estrogens, Methyltestosterone page

“If you take conjugated estrogens with methyltestosterone (Premarin with Methyltestosterone), a hormone combination used for menopausal symptoms, read the six major-rated entries here before adding any supplement. Most of the 226 ingredients on file change how your body handles the hormones themselves.”

Reviewed by 2 · Jul 18, 2026

Open the Conjugated Estrogens, Methyltestosterone interaction page

How much people look this up

Where Hollyhock and Conjugated Estrogens, Methyltestosterone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Hollyhock
Steady interest

#1,447 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Conjugated Estrogens, Methyltestosterone
Top half

#1,201 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Hollyhock reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Hollyhock and Conjugated Estrogens, Methyltestosterone records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Hollyhock

What is Hollyhock?

  • Sore throat and cough
  • Digestive upset
  • Soothing irritated skin
  • Mild inflammation
  • Urinary discomfort

Hollyhock is a flowering plant in the mallow family that has been used in traditional medicine, mainly as a soothing (demulcent) remedy for the throat, gut, and skin. Solid human studies are very limited, so its benefits are not well proven. It is generally considered gentle, but you should still talk to a pharmacist or doctor before using it, especially if you are pregnant or breastfeeding.

Alcea rosea · Malvaceae · Flowers, leaves, and roots · Tea, dried flowers, extracts, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Hollyhock is a good idea for someone in your situation. Here is what our Hollyhock record says about it on its own.

Hollyhock: dosing

There is no well-established, standardized dose for hollyhock. Traditional use most often involves a tea made from the dried flowers or leaves.Because products vary in strength and form, the safest approach is to follow the directions on the product label and not exceed the recommended amount.

From our Hollyhock monograph — the full record covers uses, side effects and every documented interaction.

Read the full Hollyhock monograph & all interactions
Keep checking

Other Drugs & Hollyhock

Browse every other medication we’ve checked against Hollyhock — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Hollyhock page.

No interaction 2,743 drugs checked — show the list
Evidence & sources

Hollyhock References

The 1 references that drive our Hollyhock monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Zhang Y, Jin L, Chen Q, et al. Hypoglycemic activity evaluation and chemical study on hollyhock flowers. Fitoterapia 2015;102:7-14. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Hollyhock and Conjugated Estrogens, Methyltestosterone Together: Common Questions

Is it safe to take Hollyhock with Conjugated Estrogens, Methyltestosterone?
We do not list a known interaction between Hollyhock and Conjugated Estrogens, Methyltestosterone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Hollyhock and Conjugated Estrogens, Methyltestosterone combination checked?
Interactions in our licensed database are recorded against drug classes. Conjugated Estrogens, Methyltestosterone is filed under 9 classifications, and Hollyhock has documented interactions with 1 drug class — none of Conjugated Estrogens, Methyltestosterone's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Hollyhock interact with any other medications?
Yes. Hollyhock has 86 documented drug interactions in our database — Conjugated Estrogens, Methyltestosterone is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Conjugated Estrogens, Methyltestosterone interact with any supplements?
Yes. Conjugated Estrogens, Methyltestosterone has documented interactions with 226 supplements in our database — Hollyhock is not one of them. The Conjugated Estrogens, Methyltestosterone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Conjugated Estrogens, Methyltestosterone and Hollyhock?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.