Drug & supplement interaction

Lactobacillus Jensenii + Acetaminophen, Butalbital, Caffeine

Acetaminophen, Butalbital, Caffeine brand names: Tecnal, Esgic Plus, Fiogesic, Triad, Repan, and others.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Lactobacillus Jensenii and Acetaminophen, Butalbital, Caffeine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Lactobacillus Jensenii and Acetaminophen, Butalbital, Caffeine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Acetaminophen, Butalbital, Caffeine and Lactobacillus Jensenii in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Lactobacillus Jensenii safety at a glance

Lactobacillus Jens... overall Use caution Generally considered low risk for healthy people, but supplement evidence is limited and quality varies.
Pregnancy Use caution Not well studied as a supplement in pregnancy; speak with your doctor before using.
Breastfeeding Use caution Little safety data exists for use while breastfeeding; check with your doctor first.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Acetaminophen, Butalbital, Caffeine and Lactobacillus Jensenii? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Acetaminophen, Butalbital, Caffeine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Acetaminophen, Butalbital, Caffeine is filed under 13 classifications — including caffeine, methylxanthines, barbiturates. Lactobacillus Jensenii has documented interactions with 1 drug class — the most serious being antibiotic drugs (moderate) — and none of Acetaminophen, Butalbital, Caffeine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Lactobacillus Jensenii Does Interact With Other Medications

Lactobacillus Jensenii has 182 moderate known drug interactions in our database — Acetaminophen, Butalbital, Caffeine isn’t one of them. If you take anything else, check it against the full list below.

Moderate 182 No known interaction 2,648 (incl. Acetaminophen, Butalbital, Caffeine)
Taking anything else?

Check Another of Your Medications Against Lactobacillus Jensenii

Covers the 2,830 medications we’ve checked against Lactobacillus Jensenii. Pick one to open its full report.

What to actually watch for

What Lactobacillus Jensenii Itself Has Been Linked To

This is not an interaction — nothing below involves Acetaminophen, Butalbital, Caffeine. It is the side-effect record for Lactobacillus Jensenii on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Lactobacillus Jensenii, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • A higher chance of infection Worth acting on Additional detail

    “Since Lactobacillus jensenii preparations contain live and active microorganisms, there is some concern that they might cause pathogenic infection in some patients. L. jensenii has been isolated in cases of bacteremia, sepsis, prostate abscess, perinephric abscess, endocarditis, and pulmonary septic emboli.”

    Lactobacillus Jensenii · Natural Medicines adverse-effect record, reported in sepsis.

    5 sources cited
    1. 107543. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
    2. 110917. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
    3. 110918. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
    4. 110920. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
    5. 110921. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.

Everything above comes from the Natural Medicines adverse-effect record for Lactobacillus Jensenii — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Acetaminophen, Butalbital, Caffeine’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Acetaminophen, Butalbital, Caffeine column appears here.

Everything else you take

See Every Supplement That Interacts With Acetaminophen, Butalbital, Caffeine

This page covers Lactobacillus Jensenii only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Acetaminophen, Butalbital, Caffeine page lists 252 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Ephedra (major) and Grapefruit (major).

By severity: 11 major · 197 moderate · 44 minor.

From our pharmacist’s overview on the Acetaminophen, Butalbital, Caffeine page

“Alcohol is the interaction I would flag first for anyone taking acetaminophen, butalbital, and caffeine (Esgic, Fiogesic, and others). Drinking raises the risk of liver injury from the acetaminophen component, and 38 of the 252 supplement ingredients on file carry that same liver concern.”

Reviewed by 2 · Jul 18, 2026

Open the Acetaminophen, Butalbital, Caffeine interaction page

How much people look this up

Where Lactobacillus Jensenii and Acetaminophen, Butalbital, Caffeine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lactobacillus Jensenii
Steady interest

#1,067 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Acetaminophen, Butalbital, Caffeine
Top 5%

#65 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Lactobacillus Jensenii reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Lactobacillus Jensenii and Acetaminophen, Butalbital, Caffeine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Lactobacillus Jensenii

What is Lactobacillus Jensenii?

  • Vaginal health
  • Maintaining healthy vaginal flora
  • Bacterial vaginosis support
  • Yeast infection support
  • General probiotic use

Lactobacillus jensenii is one of the natural 'good' bacteria found in a healthy vagina, and it is sometimes added to probiotic products marketed for vaginal health. While its role in the body is well recognized, there is only limited human research on taking it as a supplement, so the benefits are not proven. Talk with your pharmacist or doctor before using it, especially if you have a weakened immune system.

Lactobacillus jensenii · Lactobacillaceae · Whole live bacteria (probiotic strain) · Capsules, vaginal suppositories, multi-strain probiotic blends, powders

An interaction check asks whether these two react with each other — it does not ask whether Lactobacillus Jensenii is a good idea for someone in your situation. Here is what our Lactobacillus Jensenii record says about it on its own.

Lactobacillus Jensenii: dosing

There is no official or standardized dose for Lactobacillus jensenii. Probiotic amounts are often measured in colony-forming units (CFUs), and products vary widely.The best approach is to follow the directions on the product label and not exceed the recommended amount.

From our Lactobacillus Jensenii monograph — the full record covers uses, side effects and every documented interaction.

Read the full Lactobacillus Jensenii monograph & all interactions
Medication

About Acetaminophen, Butalbital, and Caffeine

What Is Acetaminophen, Butalbital, and Caffeine Used For?

Brand names: Tecnal, Esgic Plus, Fiogesic, Triad, Repan, Esgic, Fioricet

This combination product — available as capsules, tablets, and oral solution under various names including Fioricet — is used to relieve the symptoms of tension headaches (also called muscle contraction headaches).

All supported products, including Fioricet capsules and the oral solution, share this same indication. Because butalbital can be habit-forming, extended or repeated use is not recommended, and these products are not established as safe or effective for treating headaches that come back frequently over time.

See full Acetaminophen, Butalbital, and Caffeine drug information
Keep checking

Other Drugs & Lactobacillus Jensenii

Browse every other medication we’ve checked against Lactobacillus Jensenii — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
182Moderate
0Minor
2,647No known interaction
182 Moderate 2,647 No interaction
Moderate

182 interactions

Showing 60 of 182 moderate interactions — see all 182 on the Lactobacillus Jensenii page.

No interaction 2,647 drugs checked — show the list

We also checked Lactobacillus Jensenii against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,647 medications checked with no known interaction — see the full Lactobacillus Jensenii list.

See the full Lactobacillus Jensenii interactions page
See every supplement checked against Acetaminophen, Butalbital, Caffeine, ranked by severity
Evidence & sources

Lactobacillus Jensenii References

The 6 references that drive our Lactobacillus Jensenii monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  3. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  4. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  5. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  6. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Lactobacillus Jensenii and Acetaminophen, Butalbital, Caffeine Together: Common Questions

Is it safe to take Lactobacillus Jensenii with Acetaminophen, Butalbital, Caffeine?
We do not list a known interaction between Lactobacillus Jensenii and Acetaminophen, Butalbital, Caffeine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Lactobacillus Jensenii and Acetaminophen, Butalbital, Caffeine combination checked?
Interactions in our licensed database are recorded against drug classes. Acetaminophen, Butalbital, Caffeine is filed under 13 classifications, and Lactobacillus Jensenii has documented interactions with 1 drug class — none of Acetaminophen, Butalbital, Caffeine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Lactobacillus Jensenii interact with any other medications?
Yes. Lactobacillus Jensenii has 182 documented drug interactions in our database — Acetaminophen, Butalbital, Caffeine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Acetaminophen, Butalbital, Caffeine interact with any supplements?
Yes. Acetaminophen, Butalbital, Caffeine has documented interactions with 252 supplements in our database — Lactobacillus Jensenii is not one of them. The Acetaminophen, Butalbital, Caffeine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Lactobacillus Jensenii monograph Uses, safety profile, and every drug interaction in one place Acetaminophen, Butalbital, and Caffeine drug information The full plain-English guide to this medication Acetaminophen, Butalbital, Caffeine supplement interactions Every supplement checked against Acetaminophen, Butalbital, Caffeine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 6 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Acetaminophen, Butalbital, Caffeine and Lactobacillus Jensenii?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.