Drug & supplement interaction

Lauric Acid + Crizotinib

Crizotinib brand name: Xalkori.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Lauric Acid and Crizotinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Lauric Acid and Crizotinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Crizotinib and Lauric Acid in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Lauric Acid at all — not against Crizotinib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Lauric Acid safety at a glance

Lauric Acid overall Use caution Generally fine in food amounts, but high-dose supplements lack strong safety data.
Pregnancy Likely Safe When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of lauric acid when used in medicinal... Read the full pregnancy detail
Breastfeeding Likely Safe When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of lauric acid when used in medicinal... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Crizotinib and Lauric Acid? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Lauric Acid and Crizotinib May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Nausea reported in 8.8% of FDA reports for Crizotinib Additional detail

    Lauric Acid

    “Orally, nausea appears to be fairly common when lauric acid is infused into the duodenum at a rate of 0.4 kcal/minute or faster. The rate of nausea with oral administration is unknown.”

    Lauric Acid · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 106421. McVeay C, Fitzgerald PCE, Ullrich SS, Steinert RE, Horowitz M, Feinle-Bisset C. Effects of intraduodenal administration of lauric acid and L-tryptophan, alone and combined, on gut hormones, pyloric pressures, and energy intake in healthy men. Am J Clin Nu PubMed

    Crizotinib

    Listed in the ADVERSE REACTIONS section of the FDA label for Crizotinib, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

Effects for Crizotinib come from the ADVERSE REACTIONS section of its FDA label; effects for Lauric Acid come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 12,638 voluntary FDA FAERS reports for Crizotinib that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Lauric Acid in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of lauric acid when used in medicinal amounts during pregnancy or lactation. Dietary lauric acid is excreted into breast milk.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Crizotinib

This page covers Lauric Acid only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Crizotinib page lists 157 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 8 major · 112 moderate · 37 minor.

From our pharmacist’s overview on the Crizotinib page

“Grapefruit tops my worry list for crizotinib (Xalkori), a targeted pill for ALK-positive lung cancer. It blocks the enzyme (CYP3A4) that clears crizotinib, letting levels climb and side effects with them, and it is one of eight major-rated entries among the 157 supplements and herbs on file for this drug.”

Reviewed by 2 · Jul 18, 2026

Open the Crizotinib interaction page

One more smart check

Taking Lauric Acid as Part of a Dietary Supplement Product? Check It for Interactions

We hold 154 real supplement products containing Lauric Acid, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Lauric Acid. Even though Lauric Acid itself has no known interaction with Crizotinib, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Lauric Acid and Crizotinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lauric Acid
Steady interest

#1,081 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Crizotinib
Top half

#1,368 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Lauric Acid reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Lauric Acid and Crizotinib records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Lauric Acid

What is Lauric Acid?

  • Antimicrobial support
  • Skin care and acne
  • Heart and cholesterol concerns
  • Immune support
  • Energy and weight management

Lauric acid is a medium-to-long-chain saturated fatty acid found in coconut oil, palm kernel oil, and breast milk. It is studied for possible antimicrobial and skin benefits, but solid human evidence for most supplement uses is limited. As part of a normal diet it is generally fine; talk to your pharmacist or doctor before using high-dose supplements.

Fatty acid found mainly in coconut oil and palm kernel oil; also present in human breast milk · Coconut oil, MCT products, capsules, monolaurin supplements, topical products, soaps

An interaction check asks whether these two react with each other — it does not ask whether Lauric Acid is a good idea for someone in your situation. Here is what our Lauric Acid record says about it on its own.

Lauric Acid: dosing

There is no official or standardized dose of lauric acid as a supplement. Amounts vary widely between products, including coconut oil, MCT blends, and monolaurin capsules.If you choose to use a lauric acid or monolaurin product, follow the directions on the label and do not assume more is better.

From our Lauric Acid monograph — the full record covers uses, side effects and every documented interaction.

Read the full Lauric Acid monograph & all interactions
Medication

About Crizotinib

What Is Crizotinib Used For?

Brand name: Xalkori

Xalkori (crizotinib) is used to treat adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumors test positive for the ALK or ROS1 gene abnormality, as confirmed by an FDA-approved test.

Xalkori is also used to treat pediatric patients aged 1 year and older and young adults with relapsed or refractory systemic ALK-positive anaplastic large cell lymphoma (ALCL). Additionally, it treats adult and pediatric patients aged 1 year and older with unresectable, recurrent, or refractory ALK-positive inflammatory myofibroblastic tumor (IMT). Note: Xalkori's safety and effectiveness in older adults with relapsed or refractory ALK-positive ALCL have not been established.

Most-Reported Side Effects for Crizotinib

From FAERS, the FDA’s public side-effect reporting system (12,638 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Disease progression 1,216 reports
Nausea 1,118 reports
Neoplasm progression 1,112 reports
Diarrhea 846 reports
Vomiting 795 reports
See full Crizotinib drug information
Keep checking

Other Drugs & Lauric Acid

Browse every other medication we’ve checked against Lauric Acid — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Lauric Acid References

The 8 references that drive our Lauric Acid monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Brown KE, Leong K, Huang CH, et al. Gelatin/chondroitin 6-sulfate microspheres for the delivery of therapeutic proteins to the joint. Arthritis Rheum 1998;41:2185-95. PubMed
  2. de Roos N, Schouten E, Katan M. Consumption of a solid fat rich in lauric acid results in a more favorable serum lipid profile in healthy men and women than consumption of a solid fat rich in trans-fatty acids. J Nutr 2001;131;242-5. PubMed
  3. Temme EH, Mensink RP, Hornstra G. Comparison of the effects of diets enriched in lauric, palmitic, or oleic acids on serum lipids and lipoproteins in healthy women and men. Am J Clin Nutr 1996;63:897-903. PubMed
  4. Denke MA, Grundy SM. Comparison of effects of lauric acid and palmitic acid on plasma lipids and lipoproteins. Am J Clin Nutr 1992;56:895-8. PubMed
  5. Tholstrup T, Marckmann P, Vessby B, Sandstrom B. Effect of fats high in individual saturated fatty acids on plasma lipoprotein[a] levels in young healthy men. J Lipid Res 1995;36;1447-52. DOI
  6. Francois CA, Connor SL, Wander RC, Connor WE. Acute effects of dietary fatty acids on the fatty acids of human milk. Am J Clin Nutr 1998;67:301-8. PubMed
  7. Tholstrup T, Marckmann P, Jespersen J, Sandstrom B. Fat high in stearic acid favorably affects blood lipids and factor VII coagulant activity in comparison with fats high in palmitic acid or high in myristic and lauric acids. Am J Clin Nutr 1994;59:371-7. PubMed
  8. McVeay C, Fitzgerald PCE, Ullrich SS, Steinert RE, Horowitz M, Feinle-Bisset C. Effects of intraduodenal administration of lauric acid and L-tryptophan, alone and combined, on gut hormones, pyloric pressures, and energy intake in healthy men. Am J Clin Nu PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Lauric Acid and Crizotinib Together: Common Questions

Is it safe to take Lauric Acid with Crizotinib?
We do not list a known interaction between Lauric Acid and Crizotinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Lauric Acid and Crizotinib have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Crizotinib interact with any supplements?
Yes. Crizotinib has documented interactions with 157 supplements in our database — Lauric Acid is not one of them. The Crizotinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Crizotinib and Lauric Acid?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.