Drug & supplement interaction

Linden + Pacritinib

Pacritinib brand name: Vonjo.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Linden and Pacritinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Linden and Pacritinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Pacritinib and Linden in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Linden safety at a glance

Linden overall Use caution Generally well tolerated as a tea, but human safety data are limited.
Pregnancy Avoid Not enough safety information, so avoiding it is the safer choice.
Breastfeeding Use caution Safety is not well studied; check with your doctor before use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Pacritinib and Linden? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Pacritinib

Interactions in our licensed database are recorded against drug classes, not just single drug names. Pacritinib is filed under 5 classifications — including cytochrome p450 1a2 (cyp1a2) inhibitors, qt interval-prolonging drugs, cytochrome p450 3a4 (cyp3a4) inhibitors. Linden has documented interactions with 1 drug class — the most serious being lithium (moderate) — and none of Pacritinib’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Linden Does Interact With Other Medications

Linden has 1 moderate known drug interaction in our database — Pacritinib isn’t one of them. If you take anything else, check it against the full list below.

Moderate 1 No known interaction 2,829 (incl. Pacritinib)
Taking anything else?

Check Another of Your Medications Against Linden

Covers the 2,830 medications we’ve checked against Linden. Pick one to open its full report.

What to actually watch for

What Linden Itself Has Been Linked To

This is not an interaction — nothing below involves Pacritinib. It is the side-effect record for Linden on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Linden, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Hives / An allergic reaction Worth acting on Additional detail

    “Orally, there is one case report of allergic reaction to linden pollen in a linden flower tea (12). Topically, there is one case report of contact urticaria following the use of a linden extract-containing shampoo (12).”

    Linden · Natural Medicines adverse-effect record, reported in urticaria.

    1 source cited
    1. 12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

Everything above comes from the Natural Medicines adverse-effect record for Linden — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Pacritinib’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Pacritinib column appears here.

Everything else you take

See Every Supplement That Interacts With Pacritinib

This page covers Linden only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Pacritinib page lists 158 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 8 major · 110 moderate · 40 minor.

From our pharmacist’s overview on the Pacritinib page

“Someone on pacritinib (Vonjo) is usually fighting myelofibrosis, and the supplements people reach for during cancer treatment, herbal blends, immune boosters, St. John's wort for mood, are where this list gets serious.”

Reviewed by 2 · Jul 18, 2026

Open the Pacritinib interaction page

One more smart check

Taking Linden as Part of a Dietary Supplement Product? Check It for Interactions

We hold 178 real supplement products containing Linden, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Linden. Even though Linden itself has no known interaction with Pacritinib, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Linden and Pacritinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Linden
Top half

#547 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Pacritinib
Top half

#1,163 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Linden reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Linden and Pacritinib records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Linden

What is Linden?

  • Anxiety and stress
  • Trouble sleeping
  • Colds and flu symptoms
  • Cough and sore throat
  • Mild digestive upset
  • Promoting sweating during fever

Linden (also called lime flower) is a traditional herbal tea long used to calm nerves, ease cold symptoms, and support restful sleep. Strong human evidence for these uses is lacking, but the flowers are generally considered safe as an occasional tea for most healthy adults. Talk with your pharmacist or doctor before using it regularly, especially during pregnancy, breastfeeding, or if you have a health condition.

Tilia cordata, Tilia platyphyllos · Malvaceae · Dried flowers (and bracts), sometimes leaves · Tea (infusion), tincture, liquid extract, capsules

An interaction check asks whether these two react with each other — it does not ask whether Linden is a good idea for someone in your situation. Here is what our Linden record says about it on its own.

Linden: dosing

There is no official standardized dose for linden. Traditionally it is taken as a tea made by steeping a small amount of the dried flowers in hot water, often once or a few times a day.Because products vary in strength, the best approach is to follow the directions on the product label.

From our Linden monograph — the full record covers uses, side effects and every documented interaction.

Read the full Linden monograph & all interactions
Medication

About Pacritinib

What Is Pacritinib Used For?

Brand name: Vonjo

Vonjo (pacritinib) is used to treat adults with intermediate or high-risk myelofibrosis (MF) — a serious bone marrow disease — including primary MF and secondary MF that developed after polycythemia vera or essential thrombocythemia (other blood disorders). It is specifically approved for patients whose platelet count is below 50 × 10⁹/L (very low platelets), a group that has limited treatment options.

This approval is based on demonstrated reductions in spleen size. Continued approval may depend on results from confirmatory trials showing broader clinical benefit.

See full Pacritinib drug information
Keep checking

Other Drugs & Linden

Browse every other medication we’ve checked against Linden — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
1Moderate
0Minor
2,828No known interaction
1 Moderate 2,828 No interaction
Moderate

1 interaction

No interaction 2,828 drugs checked — show the list

We also checked Linden against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,828 medications checked with no known interaction — see the full Linden list.

See the full Linden interactions page
See every supplement checked against Pacritinib, ranked by severity
Evidence & sources

Linden References

The 2 references that drive our Linden monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Linden and Pacritinib Together: Common Questions

Is it safe to take Linden with Pacritinib?
We do not list a known interaction between Linden and Pacritinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Linden and Pacritinib combination checked?
Interactions in our licensed database are recorded against drug classes. Pacritinib is filed under 5 classifications, and Linden has documented interactions with 1 drug class — none of Pacritinib's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Linden interact with any other medications?
Yes. Linden has 1 documented drug interaction in our database — Pacritinib is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Pacritinib interact with any supplements?
Yes. Pacritinib has documented interactions with 158 supplements in our database — Linden is not one of them. The Pacritinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Linden monograph Uses, safety profile, and every drug interaction in one place Pacritinib drug information The full plain-English guide to this medication Pacritinib supplement interactions Every supplement checked against Pacritinib, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Pacritinib and Linden?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.