Drug & supplement interaction

Lingonberry + Imiquimod

Imiquimod brand names: Aldara, Zyclara, Vyloma.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Lingonberry and Imiquimod in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Lingonberry and Imiquimod

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Imiquimod and Lingonberry in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Lingonberry at all — not against Imiquimod, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Lingonberry safety at a glance

Lingonberry overall Use caution The berry is generally safe as food, but concentrated supplements are less studied.
Pregnancy Likely Unsafe When used orally because some constituents have mutagenic effects, potentially harming the developing fetus; avoid using. Read the full pregnancy detail
Breastfeeding Likely Unsafe When used orally because some constituents have mutagenic effects, potentially harming the developing fetus; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Imiquimod and Lingonberry? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Lingonberry Itself Has Been Linked To

This is not an interaction — nothing below involves Imiquimod. It is the side-effect record for Lingonberry on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Lingonberry, this list is the first place to look.

  • Vomiting / Nausea Additional detail

    “Orally, lingonberry seems to be well tolerated. It may cause nausea and vomiting in some patients due to its high tannin content (18).”

    Lingonberry · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    “Orally, lingonberry may cause nausea and vomiting in some patients due to its high tannin content (18).”

    Lingonberry · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Everything above comes from the Natural Medicines adverse-effect record for Lingonberry — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Imiquimod’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Imiquimod column appears here.

Special populations

Lingonberry in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Unsafe

When used orally because some constituents have mutagenic effects, potentially harming the developing fetus; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Imiquimod

This page covers Lingonberry only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Imiquimod page lists 3 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).

By severity: 2 moderate · 1 minor.

From our pharmacist’s overview on the Imiquimod page

“Imiquimod (Aldara, Zyclara, Vyloma) is a cream for warts, precancerous spots, and certain skin cancers, and its supplement list is short and workable for most people. Only 3 ingredients are on file, none rated major, and all involve products applied to the skin rather than swallowed.”

Reviewed by 2 · Jul 18, 2026

Open the Imiquimod interaction page

One more smart check

Taking Lingonberry as Part of a Dietary Supplement Product? Check It for Interactions

We hold 67 real supplement products containing Lingonberry, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Lingonberry. Even though Lingonberry itself has no known interaction with Imiquimod, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Lingonberry and Imiquimod Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lingonberry
Steady interest

#867 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Imiquimod
Steady interest

#1,982 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Lingonberry reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Lingonberry and Imiquimod records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Lingonberry

What is Lingonberry?

  • Urinary tract health
  • Antioxidant support
  • Heart and metabolic health
  • Inflammation

Lingonberry is a tart red berry rich in antioxidants such as anthocyanins and the compound arbutin, and it is popular as a food and folk remedy for urinary tract and general wellness. Human evidence for specific health benefits is still limited, so it is best enjoyed as part of a healthy diet rather than relied on to treat any condition. Talk to your pharmacist or doctor before using concentrated extracts, especially if you are pregnant, breastfeeding, or have a medical condition.

Vaccinium vitis-idaea · Ericaceae · Berries and leaves · Juice, dried berries, jam, capsules, extracts, tea (from leaves)

An interaction check asks whether these two react with each other — it does not ask whether Lingonberry is a good idea for someone in your situation. Here is what our Lingonberry record says about it on its own.

Lingonberry: dosing

There is no official or standardized dose for lingonberry supplements. The amount of active compounds can vary widely between products such as juices, dried berries, capsules, and extracts.If you choose to use a lingonberry product, follow the directions on the product label and do not exceed the recommended amount. Eating the berries as food is a simple and generally safe way to enjoy them.

From our Lingonberry monograph — the full record covers uses, side effects and every documented interaction.

Read the full Lingonberry monograph & all interactions
Medication

About Imiquimod Topical

What Is Imiquimod Topical Used For?

Brand names: Aldara, Zyclara, Vyloma

Imiquimod cream is used to treat three skin conditions in adults: actinic keratoses (rough, scaly patches on the skin caused by sun damage) on the face or scalp; superficial basal cell carcinoma (a type of skin cancer) on the trunk, neck, or limbs when surgery is not the best option; and external genital and perianal warts (condyloma acuminata) in patients 12 years and older.

It is not effective for molluscum contagiosum in children ages 2–12, and it has not been proven safe or effective in people with weakened immune systems. It should not be used for warts inside the urethra, vagina, cervix, rectum, or anal canal.

Most-Reported Side Effects for Imiquimod

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Erythema 183 reports
Fatigue 179 reports
Nausea 114 reports
Influenza like illness 102 reports
Application site erythema 100 reports
See full Imiquimod Topical drug information
Keep checking

Other Drugs & Lingonberry

Browse every other medication we’ve checked against Lingonberry — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Lingonberry References

The 4 references that drive our Lingonberry monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Kontiokari T, Sundqvist K, Nuutinen M, et al. Randomised trial of cranberry-lingonberry juice and Lactobacillus GG drink for the prevention of urinary tract infections in women. BMJ 2001;322:1571.
  3. Ferrara, P., Romaniello, L., Vitelli, O., Gatto, A., Serva, M., and Cataldi, L. Cranberry juice for the prevention of recurrent urinary tract infections: a randomized controlled trial in children. Scand.J Urol.Nephrol. 2009;43(5):369-372. PubMed
  4. Pärnnen P, Nikula-Ijs P, Sorsa T. Antimicrobial and Anti-inflammatory Lingonberry Mouthwash - A Clinical Pilot Study in the Oral Cavity. Microorganisms. 2019;7(9):331. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Lingonberry and Imiquimod Together: Common Questions

Is it safe to take Lingonberry with Imiquimod?
We do not list a known interaction between Lingonberry and Imiquimod. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Imiquimod interact with any supplements?
Yes. Imiquimod has documented interactions with 3 supplements in our database — Lingonberry is not one of them. The Imiquimod interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Imiquimod and Lingonberry?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.