Drug & supplement interaction

Mantra Meditation + Riociguat

Riociguat brand name: Adempas.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Mantra Meditation and Riociguat in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Mantra Meditation and Riociguat

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Riociguat and Mantra Meditation in our sources. This does not guarantee that the combination is completely free of risk — research on Mantra Meditation alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Mantra Meditation at all — not against Riociguat, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Mantra Meditation is a practice rather than something you take. Ask your care team whether the type and intensity you plan to practice are appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Mantra Meditation safety at a glance

Mantra Meditation overall Generally safe For most people this is a low-risk practice with no physical product to ingest.
Pregnancy Generally safe Gentle meditation is generally considered safe during pregnancy, but check with your provider.
Breastfeeding Generally safe No nursing infant is exposed to any substance, so it is generally considered safe.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Riociguat and Mantra Meditation? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Riociguat’s Own FDA Label Lists

This is not an interaction — none of it involves Mantra Meditation. These are the most notable effects listed in the ADVERSE REACTIONS section of Riociguat’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you practice Mantra Meditation and take the medicine. 3 of them are worth acting on rather than waiting out — marked below.

  • Trouble swallowing Worth acting on
  • Anemia Worth acting on
  • Bleeding or bruising Worth acting on
  • Heartburn
  • Bloating or gas
  • A stuffy or runny nose
  • A fast or pounding heartbeat
  • Low blood pressure
  • Stomach upset
  • Constipation

Showing the 10 most notable of 16 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Riociguat. Read the label on DailyMed › Mantra Meditation’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Mantra Meditation side to compare — that is a limit of the record, not a statement that Mantra Meditation has no side effects.

Overlapping uses

What Riociguat Is Prescribed For, and What Mantra Meditation Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Riociguat is a prescription medicine with approved uses on its FDA label. Mantra Meditation is a practice: what follows is what researchers have looked at it for, and how strong that evidence is.

Riociguat is prescribed for: Riociguat tablets — sold under the brand names Adempas and Riociguat — are approved for adults with two types of high blood pressure in the lungs. The first is chronic thromboembolic pulmonary hypertension (CTEPH), a condition caused by blood clots that have blocked or narrowed the arteries in the lungs. Riociguat is used when surgery has not fully fixed the problem, or when surgery is not an option. The second is pulmonary arterial hypertension (PAH), a progressive disease where the arteries in the lungs become stiff and narrowed.

Read the rest of what Riociguat is prescribed for

In PAH, riociguat helps improve exercise ability, functional class (how well you can get around day-to-day), and slows disease worsening. It can be used alone or combined with other PAH medicines called endothelin receptor antagonists or prostanoids.

Mantra Meditation has been studied for:

  • Hypertension Natural Medicines rates the evidence for Mantra Meditation: Possibly Effective Read what the research shows

    Mantra Meditation for hypertension

    Practicing transcendental meditation, a type of mantra meditation, may slightly reduce blood pressure in patients with hypertension. It is unclear if mantra meditation is more effective than health education in these patients.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Riociguat on your own; if you are taking Mantra Meditation for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Riociguat

This page covers Mantra Meditation only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Riociguat page lists 230 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Grapefruit (major) and St. John's Wort (major).

By severity: 6 major · 187 moderate · 37 minor.

From our pharmacist’s overview on the Riociguat page

“Riociguat (Adempas) works by relaxing the blood vessels in your lungs, which also lowers blood pressure, so I read this list of 230 supplements and herbs with real concern, and the six rated major are what to understand first. Grapefruit can push riociguat levels up and intensify its effect, while St.”

Reviewed by 2 · Jul 18, 2026

Open the Riociguat interaction page

How much people look this up

Where Mantra Meditation and Riociguat Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Mantra Meditation
Steady interest

#1,077 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Riociguat
Steady interest

#1,556 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Mantra Meditation is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Mantra Meditation reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Mantra Meditation and Riociguat records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Mind-body practice

About Mantra Meditation

What is Mantra Meditation?

  • Stress reduction
  • Anxiety
  • Relaxation and focus
  • Sleep difficulties
  • Blood pressure support
  • Spiritual or contemplative practice

Mantra meditation is a mind-body practice in which you silently or quietly repeat a word, sound, or phrase to calm the mind and reduce stress. It is generally very safe for most people and may help with stress, anxiety, and relaxation, though the quality of research varies. It is not a substitute for medical care, so talk with your doctor or pharmacist about any health condition you hope to manage.

Not applicable (a mind-body practice, not a plant or substance) · Silent or spoken repetition of a word, sound, or phrase; guided audio; group or individual practice; programs such as Transcendental Meditation

An interaction check asks whether these two react with each other — it does not ask whether Mantra Meditation is a good idea for someone in your situation. Here is what our Mantra Meditation record says about it on its own.

Mantra Meditation: dosing

There is no standardized "dose" for mantra meditation. Many programs and teachers suggest practicing for about 10 to 20 minutes once or twice a day, but you can start with just a few minutes and build up as you feel comfortable.Consistency tends to matter more than length—practicing a little each day is often more helpful than one long session now and then.

From our Mantra Meditation monograph — the full record covers uses, side effects and every documented interaction.

Read the full Mantra Meditation monograph & all interactions
Medication

About Riociguat

What Is Riociguat Used For?

Brand name: Adempas

Riociguat tablets — sold under the brand names Adempas and Riociguat — are approved for adults with two types of high blood pressure in the lungs. The first is chronic thromboembolic pulmonary hypertension (CTEPH), a condition caused by blood clots that have blocked or narrowed the arteries in the lungs. Riociguat is used when surgery has not fully fixed the problem, or when surgery is not an option.

The second is pulmonary arterial hypertension (PAH), a progressive disease where the arteries in the lungs become stiff and narrowed. In PAH, riociguat helps improve exercise ability, functional class (how well you can get around day-to-day), and slows disease worsening. It can be used alone or combined with other PAH medicines called endothelin receptor antagonists or prostanoids.

Most-Reported Side Effects for Riociguat

From FAERS, the FDA’s public side-effect reporting system (32,415 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dyspnea 5,718 reports
Headache 4,513 reports
Nausea 3,769 reports
Diarrhea 3,533 reports
Dizziness 3,522 reports
See full Riociguat drug information
Keep checking

Other Drugs & Mantra Meditation

Browse every other medication we’ve checked against Mantra Meditation — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Mantra Meditation against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Mantra Meditation list.

See the full Mantra Meditation interactions page
See every supplement checked against Riociguat, ranked by severity
Evidence & sources

Mantra Meditation References

The 3 sources that drive our Mantra Meditation monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Mantra Meditation is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Meditation and Mindfulness: What You Need To Know — NIH NCCIH Source
  2. Meditation: In Depth — NIH NCCIH Source
  3. Meditation — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Practicing Mantra Meditation While Taking Riociguat: Common Questions

Is it safe to practice Mantra Meditation while taking Riociguat?
We do not list a known interaction between Mantra Meditation and Riociguat. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Mantra Meditation and Riociguat used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Mantra Meditation in each. That is a conversation for your prescriber, especially if Riociguat is being adjusted to a target.
Does Riociguat interact with any supplements?
Yes. Riociguat has documented interactions with 230 supplements in our database — Mantra Meditation is not one of them. The Riociguat interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Mantra Meditation monograph Uses, safety profile, and every drug interaction in one place Riociguat drug information The full plain-English guide to this medication Riociguat supplement interactions Every supplement checked against Riociguat, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Riociguat and Mantra Meditation?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.