Drug & supplement interaction

Mentabolan + Tolazamide

Tolazamide brand name: Tolinase.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Mentabolan and Tolazamide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Mentabolan and Tolazamide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tolazamide and Mentabolan in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Mentabolan at all — not against Tolazamide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Mentabolan safety at a glance

Mentabolan overall Avoid It is a synthetic steroid-type compound with real risks and little reliable safety data.
Pregnancy Possibly Unsafe When used orally. Prohormones can be converted to active hormones in the body and cause adverse effects such as menstrual irregularities, infertility, hair loss... Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally. Prohormones can be converted to active hormones in the body and cause adverse effects such as menstrual irregularities, infertility, hair loss... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tolazamide and Mentabolan? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
Special populations

Mentabolan in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally. Prohormones can be converted to active hormones in the body and cause adverse effects such as menstrual irregularities, infertility, hair loss, and acne. Prohormones have also been associated with hepatotoxicity and increased risk of cardiovascular disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing prohormones are dangerous. Avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Tolazamide

This page covers Mentabolan only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tolazamide page lists 272 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Siberian Cocklebur (major), Acai (moderate), African Wild Potato (moderate) and Agaricus Mushroom (moderate).

By severity: 2 major · 230 moderate · 40 minor.

From our pharmacist’s overview on the Tolazamide page

“Tolazamide (Tolinase) lowers blood sugar in type 2 diabetes, and I would handle its supplement list with care, because nearly everything listed can drag blood sugar lower still. Herbs and foods with glucose-lowering effects dominate the file, and stacked on a pill that already lowers glucose they raise the odds of hypoglycemia, blood s…”

Reviewed by 2 · Jul 18, 2026

Open the Tolazamide interaction page

One more smart check

Taking Mentabolan as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Mentabolan, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Mentabolan. Even though Mentabolan itself has no known interaction with Tolazamide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Mentabolan and Tolazamide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Mentabolan
Top half

#638 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tolazamide
Top half

#1,086 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Mentabolan reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Mentabolan and Tolazamide records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Mentabolan

What is Mentabolan?

  • Muscle building and strength
  • Athletic performance enhancement
  • Body recomposition
  • Sold as a 'prohormone' bodybuilding supplement

Mentabolan is a marketing name for a synthetic steroid-like compound (often linked to dimethandrostenediol/prohormone chemicals) sold in some bodybuilding 'prohormone' products, not a natural herb. These designer steroid products can be unsafe, may be illegal or unapproved, and have been associated with liver and hormonal harm, so we strongly recommend avoiding them and talking with a doctor or pharmacist.

Not applicable (synthetic compound) · Capsules, tablets

An interaction check asks whether these two react with each other — it does not ask whether Mentabolan is a good idea for someone in your situation. Here is what our Mentabolan record says about it on its own.

Mentabolan: dosing

There is no established, safe, or medically recommended dose for Mentabolan. It is not an approved medication or a tested supplement, and product labels may be inaccurate.Because of the serious safety concerns, we do not recommend using it at any dose.

From our Mentabolan monograph — the full record covers uses, side effects and every documented interaction.

Read the full Mentabolan monograph & all interactions
Medication

About Tolazamide

What Is Tolazamide Used For?

Brand name: Tolinase

  • Tolazamide is used along with diet and exercise, and sometimes with other medications, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Tolazamide is in a class of medications called sulfonylureas. Tolazamide lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. This medication will only help lower blood sugar in people whose bodies produce insulin naturally. Tolazamide is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may occur if high blood sugar is not treated).

  • Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

See full Tolazamide drug information
Keep checking

Other Drugs & Mentabolan

Browse every other medication we’ve checked against Mentabolan — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Mentabolan References

The 1 references that drive our Mentabolan monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Mentabolan and Tolazamide Together: Common Questions

Is it safe to take Mentabolan with Tolazamide?
We do not list a known interaction between Mentabolan and Tolazamide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Tolazamide interact with any supplements?
Yes. Tolazamide has documented interactions with 272 supplements in our database — Mentabolan is not one of them. The Tolazamide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Tolazamide and Mentabolan?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.