Drug & supplement interaction

Methyldiazinol + Eluxadoline

Eluxadoline brand name: Viberzi.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Methyldiazinol and Eluxadoline in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Eluxadoline states a food rule worth keeping to.

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Interaction report

Methyldiazinol and Eluxadoline

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Eluxadoline and Methyldiazinol in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Methyldiazinol at all — not against Eluxadoline, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Methyldiazinol safety at a glance

Methyldiazinol overall Not established There is no reliable safety data for a substance by this name.
Pregnancy Possibly Unsafe When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced ferti... Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced ferti... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Eluxadoline and Methyldiazinol? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Eluxadoline’s Own FDA Label Lists

This is not an interaction — none of it involves Methyldiazinol. These are the most notable effects listed in the ADVERSE REACTIONS section of Eluxadoline’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 8 of them are worth acting on rather than waiting out — marked below.

  • Pancreatitis Worth acting on mentioned in 9.5% of FDA reports for Eluxadoline
  • Wheezing Worth acting on
  • Chest pain Worth acting on
  • Shortness of breath Worth acting on
  • A severe allergic reaction Worth acting on
  • Hives Worth acting on
  • A higher chance of infection Worth acting on
  • An allergic reaction Worth acting on
  • Stomach pain mentioned in 19.2% of FDA reports for Eluxadoline
  • Heartburn

Showing the 10 most notable of 18 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Eluxadoline. Read the label on DailyMed › Where a percentage is shown, it is the share of 2,928 voluntary FDA FAERS reports for Eluxadoline that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Methyldiazinol’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Methyldiazinol side to compare — that is a limit of the record, not a statement that Methyldiazinol has no side effects.

Special populations

Methyldiazinol in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous. Avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Eluxadoline Products Have a Food Rule — Methyldiazinol Should Not Break It

At least one FDA label for a product containing Eluxadoline says to take it with food. If you take Methyldiazinol on an empty stomach out of habit, keep them separate — and take Eluxadoline with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Eluxadoline products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

2 DOSAGE AND ADMINISTRATION The recommended dosage of VIBERZI is 100 mg taken orally twice daily with food.

From the Dosage and Administration section of the FDA label we read for Eluxadoline — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

From our Q&A

Questions About Methyldiazinol or Eluxadoline

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Methyldiazinol or Eluxadoline, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Eluxadoline

This page covers Methyldiazinol only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Eluxadoline page lists 23 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), African Wild Potato (moderate), Banderol (moderate), Beer (moderate) and Caffeic Acid (moderate).

By severity: 1 major · 13 moderate · 9 minor.

From our pharmacist’s overview on the Eluxadoline page

“One supplement here can keep a dose of eluxadoline (Viberzi) from being fully absorbed. Activated charcoal soaks up oral medicines in the gut, and of the 23 supplements and herbs with an interaction on file, it is the only one rated major, reason enough to give this page a careful read.”

Reviewed by 2 · Jul 18, 2026

Open the Eluxadoline interaction page

How much people look this up

Where Methyldiazinol and Eluxadoline Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Methyldiazinol
Steady interest

#1,343 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Eluxadoline
Steady interest

#2,111 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Methyldiazinol reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Methyldiazinol and Eluxadoline records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Methyldiazinol

What is Methyldiazinol?

There is no reliable scientific or pharmaceutical information about a substance called "Methyldiazinol." It does not appear to be a recognized herb, dietary supplement, or well-documented compound, so we cannot confirm what it is, whether it works, or whether it is safe. Do not take any product marketed under this name without first verifying its identity and contents with a pharmacist or doctor.

An interaction check asks whether these two react with each other — it does not ask whether Methyldiazinol is a good idea for someone in your situation. Here is what our Methyldiazinol record says about it on its own.

Methyldiazinol: dosing

There is no established or safe dose for Methyldiazinol because the substance is not recognized or studied.We cannot recommend any amount. If a product label gives a dose, that does not mean it has been tested for safety.

From our Methyldiazinol monograph — the full record covers uses, side effects and every documented interaction.

Read the full Methyldiazinol monograph & all interactions
Medication

About Eluxadoline

What Is Eluxadoline Used For?

Brand name: Viberzi

Viberzi (eluxadoline) is approved for adults with irritable bowel syndrome with diarrhea (IBS-D) — a condition that causes chronic abdominal pain, cramping, and frequent loose stools.

It is taken orally twice daily and is intended for ongoing management of IBS-D symptoms, not as a one-time or as-needed treatment.

Most-Reported Side Effects for Eluxadoline

From FAERS, the FDA’s public side-effect reporting system (2,928 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Abdominal pain 352 reports
Diarrhea 345 reports
Constipation 283 reports
Pancreatitis 278 reports
Nausea 219 reports
See full Eluxadoline drug information
Keep checking

Other Drugs & Methyldiazinol

Browse every other medication we’ve checked against Methyldiazinol — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Methyldiazinol References

The 1 references that drive our Methyldiazinol monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Methyldiazinol and Eluxadoline Together: Common Questions

Is it safe to take Methyldiazinol with Eluxadoline?
We do not list a known interaction between Methyldiazinol and Eluxadoline. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Methyldiazinol and Eluxadoline at the same time of day?
At least one FDA label for a product containing Eluxadoline says to take it with food. If you take Methyldiazinol on an empty stomach out of habit, keep them separate and take Eluxadoline with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Eluxadoline products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Eluxadoline interact with any supplements?
Yes. Eluxadoline has documented interactions with 23 supplements in our database — Methyldiazinol is not one of them. The Eluxadoline interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Eluxadoline and Methyldiazinol?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.