Drug & supplement interaction

Music Therapy + Sertraline

Sertraline brand name: Zoloft.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Music Therapy and Sertraline in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Music Therapy and Sertraline

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Sertraline and Music Therapy in our sources. This does not guarantee that the combination is completely free of risk — research on Music Therapy alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Music Therapy at all — not against Sertraline, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Music Therapy is a treatment rather than something you take. Tell whoever provides it which medicines you use, and ask your prescriber whether it is appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Music Therapy safety at a glance

Music Therapy overall Generally safe Music therapy is non-invasive and considered very safe for most people.
Pregnancy Generally safe Listening to or making music is generally safe during pregnancy.
Breastfeeding Generally safe There is no known risk from music therapy while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Sertraline and Music Therapy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Sertraline’s Own FDA Label Lists

This is not an interaction — none of it involves Music Therapy. These are the most notable effects listed in the ADVERSE REACTIONS section of Sertraline’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you have Music Therapy and take the medicine. 7 of them are worth acting on rather than waiting out — marked below.

  • Mania or an unusually elevated mood Worth acting on
  • Serotonin syndrome Worth acting on
  • Thoughts of self-harm Worth acting on
  • Low sodium Worth acting on
  • Seizures Worth acting on
  • Bleeding or bruising Worth acting on
  • An allergic reaction Worth acting on
  • Loss of bladder control
  • A change in sex drive
  • Erection problems

Showing the 10 most notable of 32 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Sertraline. Read the label on DailyMed › Where a percentage is shown, it is the share of 214,799 voluntary FDA FAERS reports for Sertraline that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Music Therapy’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Music Therapy side to compare — that is a limit of the record, not a statement that Music Therapy has no side effects.

Overlapping uses

What Sertraline Is Prescribed For, and What Music Therapy Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Sertraline is a prescription medicine with approved uses on its FDA label. Music Therapy is a treatment: what follows is what researchers have looked at it for, and how strong that evidence is.

Sertraline is prescribed for: Sertraline treats a range of mental health conditions. All formulations are approved for major depressive disorder (MDD) in adults and obsessive-compulsive disorder (OCD). The oral solution (including Zoloft oral solution) and several tablet formulations are also approved for panic disorder, post-traumatic stress disorder (PTSD), social anxiety disorder, and premenstrual dysphoric disorder (PMDD). For OCD specifically, the capsule formulations and some tablet products are approved for use in adults and children aged 6 and older.

Read the rest of what Sertraline is prescribed for

Sertraline hydrochloride tablets (plain, not film-coated) are approved for OCD in pediatric patients as well. However, sertraline is not approved for major depressive disorder in children — only in adults.

Music Therapy has been studied for:

  • Stress studied, not established Music Therapy has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Music Therapy for stress

    It is unclear if music therapy is beneficial for stress.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Sertraline on your own; if you are taking Music Therapy for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Music Therapy or Sertraline

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Music Therapy or Sertraline, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Sertraline

This page covers Music Therapy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Sertraline page lists 188 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 9 major · 139 moderate · 40 minor.

From our pharmacist’s overview on the Sertraline page

“If you take sertraline (Zoloft) for depression, anxiety, or panic, treat this page with real care. Nine of the 188 supplements here carry a major rating, and the biggest issue is how your body clears the drug.”

Reviewed by 2 · Jul 18, 2026

Open the Sertraline interaction page

How much people look this up

Where Music Therapy and Sertraline Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Music Therapy
Steady interest

#1,241 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Sertraline
Top 10

#5 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Music Therapy reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Music Therapy and Sertraline records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Treatment approach

About Music Therapy

What is Music Therapy?

  • Anxiety and stress
  • Depression and low mood
  • Pain management
  • Dementia and memory support
  • Coping during medical procedures
  • Rehabilitation after stroke or injury

Music therapy is a non-drug, evidence-informed practice where trained therapists use music to support emotional, mental, and physical health. It is generally very safe and may help with stress, mood, pain, and quality of life, though it is best used alongside (not instead of) standard medical care.

Not applicable (a therapeutic practice, not a plant or substance) · Active music-making, listening to recorded or live music, guided sessions with a trained music therapist, group or individual sessions

An interaction check asks whether these two react with each other — it does not ask whether Music Therapy is a good idea for someone in your situation. Here is what our Music Therapy record says about it on its own.

Music Therapy: dosing

There is no standardized "dose" for music therapy, since it is a practice rather than a product. Session length, frequency, and type are usually chosen by a certified music therapist based on your goals and needs.In studies and clinical settings, sessions often last roughly 20 to 60 minutes and may be done once or several times a week, but this varies widely. Casual listening to calming music on your own is also a safe, simple way to relax.

From our Music Therapy monograph — the full record covers uses, side effects and every documented interaction.

Read the full Music Therapy monograph & all interactions
Medication

About Sertraline

What Is Sertraline Used For?

Brand name: Zoloft

Sertraline treats a range of mental health conditions. All formulations are approved for major depressive disorder (MDD) in adults and obsessive-compulsive disorder (OCD). The oral solution (including Zoloft oral solution) and several tablet formulations are also approved for panic disorder, post-traumatic stress disorder (PTSD), social anxiety disorder, and premenstrual dysphoric disorder (PMDD).

For OCD specifically, the capsule formulations and some tablet products are approved for use in adults and children aged 6 and older. Sertraline hydrochloride tablets (plain, not film-coated) are approved for OCD in pediatric patients as well. However, sertraline is not approved for major depressive disorder in children — only in adults.

Most-Reported Side Effects for Sertraline

From FAERS, the FDA’s public side-effect reporting system (218,320 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Nausea 13,865 reports
Fatigue 12,822 reports
Headache 11,106 reports
Anxiety 10,369 reports
Diarrhea 10,339 reports
See full Sertraline drug information
Keep checking

Other Drugs & Music Therapy

Browse every other medication we’ve checked against Music Therapy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Music Therapy against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Music Therapy list.

See the full Music Therapy interactions page
See every supplement checked against Sertraline, ranked by severity
Evidence & sources

Music Therapy References

The 2 references that drive our Music Therapy monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Düzgün MV, Özer Z. The effects of music intervention on breast milk production in breastfeeding mothers: A systematic review and meta-analysis of randomized controlled trials. J Adv Nurs 2020;76(12):3307-3316.
  2. Bibb J, Castle D, Newton R. The role of music therapy in reducing post meal related anxiety for patients with anorexia nervosa. J Eat Disord. 2015;3:50. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Having Music Therapy While Taking Sertraline: Common Questions

Is it safe to have Music Therapy while taking Sertraline?
We do not list a known interaction between Music Therapy and Sertraline. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Music Therapy and Sertraline used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Music Therapy in each. That is a conversation for your prescriber, especially if Sertraline is being adjusted to a target.
Does Sertraline interact with any supplements?
Yes. Sertraline has documented interactions with 188 supplements in our database — Music Therapy is not one of them. The Sertraline interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Music Therapy monograph Uses, safety profile, and every drug interaction in one place Sertraline drug information The full plain-English guide to this medication Sertraline supplement interactions Every supplement checked against Sertraline, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Sertraline and Music Therapy?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.