Drug & supplement interaction

Myrcia + Entrectinib

Entrectinib brand name: Rozlytrek.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Myrcia and Entrectinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Myrcia and Entrectinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Entrectinib and Myrcia in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Myrcia safety at a glance

Myrcia overall Not established Human safety data are very limited, so caution is advised.
Pregnancy Avoid There is not enough safety information, so avoid use during pregnancy.
Breastfeeding Avoid Safety while breastfeeding is unknown, so it is best avoided.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Entrectinib and Myrcia? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Entrectinib

Interactions in our licensed database are recorded against drug classes, not just single drug names. Entrectinib is filed under 4 classifications — including qt interval-prolonging drugs, hepatotoxic drugs, cytochrome p450 3a4 (cyp3a4) substrates. Myrcia has documented interactions with 1 drug class — the most serious being levothyroxine (synthroid, others) (moderate) — and none of Entrectinib’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Myrcia Does Interact With Other Medications

Myrcia has 3 moderate known drug interactions in our database — Entrectinib isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Myrcia

Covers the 2,830 medications we’ve checked against Myrcia. Pick one to open its full report.

What to actually watch for

What Entrectinib’s Own FDA Label Lists

This is not an interaction — none of it involves Myrcia. These are the most notable effects listed in the ADVERSE REACTIONS section of Entrectinib’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Loss of vision Worth acting on
  • Bone thinning Worth acting on
  • Muscle weakness Worth acting on
  • Memory problems Worth acting on
  • Dehydration Worth acting on
  • Trouble swallowing Worth acting on
  • High potassium Worth acting on
  • Unsteadiness Worth acting on
  • Blood clots Worth acting on
  • Hallucinations Worth acting on

Showing the 10 most notable of 53 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Entrectinib. Read the label on DailyMed › Where a percentage is shown, it is the share of 1,653 voluntary FDA FAERS reports for Entrectinib that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Myrcia’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Myrcia side to compare — that is a limit of the record, not a statement that Myrcia has no side effects.

Everything else you take

See Every Supplement That Interacts With Entrectinib

This page covers Myrcia only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Entrectinib page lists 175 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Beer (major) and Cesium (major).

By severity: 11 major · 127 moderate · 37 minor.

From our pharmacist’s overview on the Entrectinib page

“Grapefruit tops my worry list for anyone taking entrectinib (Rozlytrek), a targeted cancer therapy cleared by the liver enzyme CYP3A4. 121 of the 175 supplement ingredients on this page can shift how that enzyme handles the drug.”

Reviewed by 2 · Jul 18, 2026

Open the Entrectinib interaction page

How much people look this up

Where Myrcia and Entrectinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Myrcia
Steady interest

#1,137 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Entrectinib
Top half

#1,026 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Myrcia reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Myrcia and Entrectinib records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Myrcia

What is Myrcia?

  • Blood sugar support
  • Digestive upset and diarrhea
  • Mild urinary complaints
  • Astringent for the gut
  • Traditional 'pedra-hume-caa' folk remedy

Myrcia is a group of tropical shrubs and trees in the myrtle family, used in South American folk medicine—often as a tea—mainly for blood sugar and digestive complaints. Human evidence is very limited, so it should not replace proven treatments. Talk with your pharmacist or doctor before using it, especially if you have diabetes or take other medicines.

Myrtaceae · Leaves (and sometimes bark) · Tea, dried leaf, capsules, liquid extracts

An interaction check asks whether these two react with each other — it does not ask whether Myrcia is a good idea for someone in your situation. Here is what our Myrcia record says about it on its own.

Myrcia: dosing

There is no established standardized dose for Myrcia. Traditional use is usually as a tea made from the dried leaves, but amounts vary widely and are not backed by clinical research.If you choose to try a commercial product, follow the directions on the label and do not exceed them.

From our Myrcia monograph — the full record covers uses, side effects and every documented interaction.

Read the full Myrcia monograph & all interactions
Medication

About Entrectinib

What Is Entrectinib Used For?

Brand name: Rozlytrek

Rozlytrek (entrectinib) is used to treat adult patients with ROS1-positive metastatic non-small cell lung cancer (NSCLC), as confirmed by an FDA-approved test. It is also approved for adult and pediatric patients older than 1 month of age who have solid tumors — any cancer type — that carry an NTRK gene fusion detected by an FDA-approved test, provided the tumor has no known acquired resistance mutation, is metastatic or cannot be surgically removed without severe harm, and has progressed after prior treatment or has no satisfactory alternative therapy.

The NTRK gene fusion approval in solid tumors was granted under accelerated approval, meaning it is based on tumor response rates. Continued approval may depend on results from confirmatory clinical trials.

Most-Reported Side Effects for Entrectinib

From FAERS, the FDA’s public side-effect reporting system (1,653 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dizziness 150 reports
Disease progression 117 reports
Taste disorder 71 reports
Constipation 66 reports
Blood creatinine increased 62 reports
See full Entrectinib drug information
Keep checking

Other Drugs & Myrcia

Browse every other medication we’ve checked against Myrcia — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
3Moderate
0Minor
2,826No known interaction
Moderate

3 interactions

No interaction 2,826 drugs checked — show the list
Evidence & sources

Myrcia References

The 2 references that drive our Myrcia monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Russo EM, Reichelt AA, De Sa JR, et al. Clinical trial of Myrcia uniflora and Bauhinia forficata leaf extracts in normal and diabetic patients. Braz J Med Biol Res 1990;23(1):11-20.
  2. Ferreira AC, Neto JC, da Silva AC, et al. Inhibition of thyroid peroxidase by Myrcia uniflora flavonoids. Chem Res Toxicol 2006;19(3):351-55.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Myrcia and Entrectinib Together: Common Questions

Is it safe to take Myrcia with Entrectinib?
We do not list a known interaction between Myrcia and Entrectinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Myrcia and Entrectinib combination checked?
Interactions in our licensed database are recorded against drug classes. Entrectinib is filed under 4 classifications, and Myrcia has documented interactions with 1 drug class — none of Entrectinib's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Myrcia interact with any other medications?
Yes. Myrcia has 3 documented drug interactions in our database — Entrectinib is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Entrectinib interact with any supplements?
Yes. Entrectinib has documented interactions with 175 supplements in our database — Myrcia is not one of them. The Entrectinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Entrectinib and Myrcia?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.