Drug & supplement interaction

Myrrh + Insulin determir

Insulin determir brand name: Levemir.

Moderate Interaction
The bottom line Moderate

Myrrh has a moderate interaction with Insulin determir. Theoretically, myrrh might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Myrrh and Insulin determir

Here is the interaction we found between these two, with the evidence behind it.

Moderate

ANTIDIABETES DRUGS

Why this applies to Insulin determir

Insulin determir falls under ANTIDIABETES DRUGS — the group Myrrh interacts with.

Theoretically, myrrh might increase the risk of hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research suggests that myrrh has hypoglycemic effects.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the simple version: Levemir (insulin detemir) already lowers your blood sugar, and myrrh might nudge it down a little further. In lab and animal studies, compounds in myrrh appeared to have their own blood-sugar-lowering effect. Stack that on top of your insulin, and in theory you could dip too low (hypoglycemia).

I want to be honest about the evidence though, this is theoretical. We don't have solid human studies showing it actually happens, so I wouldn't lose sleep over it. Still, if you do add a concentrated myrrh supplement, just watch for the usual low-sugar warning signs: shakiness, sweating, dizziness, a racing heart, or confusion. Check your glucose a bit more often at first, and talk with your pharmacist or doctor before mixing the two.

References
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Al-Romaiyan A, Huang GC, Jones P, Persaud S. Commiphora myrrha stimulates insulin secretion from mouse and human islets of Langerhans. J Ethnopharmacol. 2021 Jan 10;264:113075. PubMed

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Myrrh Also Interacts With Other Medications

Myrrh has 87 moderate known drug interactions in our database — the Insulin determir one above is one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Myrrh

Covers the 2,830 medications we’ve checked against Myrrh. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Insulin determir

This page covers Myrrh only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Insulin determir page lists 242 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Chelation Therapy Products (major), Siberian Cocklebur (major), Acai (moderate), African Wild Potato (moderate) and Agaricus Mushroom (moderate).

By severity: 2 major · 211 moderate · 29 minor.

From our pharmacist’s overview on the Insulin determir page

“Anyone using insulin detemir (Levemir) should treat this list with real caution, because nearly every one of the 242 ingredients on it acts on blood sugar, and most stack extra glucose-lowering on top of the insulin you already inject. Only two carry a major rating, but both deserve understanding first: Siberian cocklebur, which has ca…”

Reviewed by 2 · Jul 18, 2026

Open the Insulin determir interaction page

One more smart check

Taking Myrrh as Part of a Dietary Supplement Product? Check It for Interactions

We hold 458 real supplement products containing Myrrh, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Myrrh. Your product may carry other ingredients that interact with Insulin determir too, on top of Myrrh — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Myrrh and Insulin determir Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Myrrh
Top half

#399 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Insulin determir
Steady interest

#2,036 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Myrrh

What is Myrrh?

Myrrh
  • Mouth and gum irritation
  • Sore throat
  • Minor wound and skin care
  • Digestive upset
  • Antimicrobial/antiseptic uses

Myrrh is a fragrant gum resin from Commiphora trees that has long been used in mouthwashes, throat remedies, and skin care. Modern evidence for most of its uses is limited and comes mostly from laboratory or small studies, so it should be viewed as a traditional remedy rather than a proven treatment. Talk with your pharmacist or doctor before using it, and avoid it during pregnancy.

Read the full Myrrh monograph & all interactions
Medication

About Insulin Detemir (rDNA Origin) Injection

What Is Insulin Detemir (rDNA Origin) Injection Used For?

Brand name: Levemir

Levemir (insulin detemir) is used to improve blood sugar (glucose) control in adults and children with type 1 diabetes or type 2 diabetes. It is a basal insulin, meaning it works around the clock to keep background blood sugar levels steady.

Levemir is not recommended for treating diabetic ketoacidosis (a dangerous buildup of acids in the blood that requires a different type of insulin).

See full Insulin Detemir (rDNA Origin) Injection drug information
Keep checking

Other Drugs & Myrrh

Browse every other medication we’ve checked against Myrrh — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
87Moderate
0Minor
2,742No known interaction
Moderate

87 interactions

Showing 60 of 87 moderate interactions — see all 87 on the Myrrh page.

No interaction 2,742 drugs checked — show the list
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Myrrh and Insulin determir Together: Common Questions

Can you take Myrrh with Insulin determir?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Myrrh and Insulin determir interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.