Drug & supplement interaction

Myrtle + Mepolizumab

Mepolizumab brand name: Nucala.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Myrtle and Mepolizumab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Myrtle and Mepolizumab

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Mepolizumab and Myrtle in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Myrtle at all — not against Mepolizumab, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Myrtle safety at a glance

Myrtle overall Use caution Likely safe in small amounts as food or tea, but concentrated extracts and oils need caution.
Pregnancy Likely Unsafe When used orally; avoid using. Read the full pregnancy detail
Breastfeeding Likely Unsafe When used orally; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Mepolizumab and Myrtle? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Myrtle and Mepolizumab May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Wheezing Worth acting on reported in 40.3% of FDA reports for Mepolizumab Additional detail

    Myrtle

    “Orally, consumption of very large amounts of undiluted myrtle leaf oil might lead to respiratory failure and collapse (18).

    Topically, facial contact with myrtle oil preparations may cause glottal or bronchial spasm, asthma-like attacks, or respiratory failure in infants and children (18).”

    Myrtle · Natural Medicines adverse-effect record, reported in asthma.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    Mepolizumab

    Listed in the ADVERSE REACTIONS section of the FDA label for Mepolizumab, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

Reported for Myrtle but not commonly for Mepolizumab: low blood pressure, constipation and dry skin.

Effects for Mepolizumab come from the ADVERSE REACTIONS section of its FDA label; effects for Myrtle come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 49,399 voluntary FDA FAERS reports for Mepolizumab that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Myrtle in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Unsafe

When used orally; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

One more smart check

Taking Myrtle as Part of a Dietary Supplement Product? Check It for Interactions

We hold 33 real supplement products containing Myrtle, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Myrtle. Even though Myrtle itself has no known interaction with Mepolizumab, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Myrtle and Mepolizumab Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Myrtle
Steady interest

#1,213 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Mepolizumab
Steady interest

#2,519 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Myrtle reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Myrtle and Mepolizumab records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Myrtle

What is Myrtle?

  • Coughs and respiratory congestion
  • Digestive upset
  • Antimicrobial and wound care
  • Skin conditions
  • Urinary complaints

Myrtle (Myrtus communis) is a Mediterranean shrub used traditionally for respiratory, digestive, and skin complaints. Modern research is mostly limited to laboratory and small studies, so its benefits in people are not well proven. Use cautiously, follow product labels, and talk to your pharmacist or doctor first—especially since the essential oil should never be swallowed.

Myrtus communis · Myrtaceae · Leaves, berries, flowers, and essential oil · Tea, capsules, extracts, essential oil, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Myrtle is a good idea for someone in your situation. Here is what our Myrtle record says about it on its own.

Myrtle: dosing

There is no well-established standard dose for myrtle. Amounts used in traditional practice and studies vary widely depending on the form—tea, extract, capsule, or oil.Because products differ in strength and quality, the safest approach is to follow the directions on the product label and not exceed them.

From our Myrtle monograph — the full record covers uses, side effects and every documented interaction.

Read the full Myrtle monograph & all interactions
Medication

About Mepolizumab Injection

What Is Mepolizumab Injection Used For?

Brand name: Nucala

Nucala is used as an add-on maintenance treatment — meaning it works alongside other medications, not instead of them. It is approved for severe asthma (in patients 6 years and older with high eosinophil levels), chronic rhinosinusitis with nasal polyps (CRSwNP) in adults 18 and older whose symptoms aren't controlled by nasal corticosteroids alone, and COPD in adults with an eosinophilic phenotype whose disease isn't adequately controlled.

Nucala is also approved to treat eosinophilic granulomatosis with polyangiitis (EGPA), a rare form of blood vessel inflammation, and hypereosinophilic syndrome (HES), a condition involving dangerously elevated eosinophil counts, in adults and adolescents 12 and older. It is not meant to relieve sudden asthma attacks or acute COPD flares.

Most-Reported Side Effects for Mepolizumab

From FAERS, the FDA’s public side-effect reporting system (49,399 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Asthma 12,767 reports
Dyspnea 10,576 reports
Wheezing 7,131 reports
Cough 5,100 reports
Therapeutic product effect incomplete 5,051 reports
See full Mepolizumab Injection drug information
Keep checking

Other Drugs & Myrtle

Browse every other medication we’ve checked against Myrtle — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Myrtle against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Myrtle list.

See the full Myrtle interactions page
See every supplement checked against Mepolizumab, ranked by severity
Evidence & sources

Myrtle References

The 3 references that drive our Myrtle monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Salmanian M, Shirbeigi L, Hashem-Dabaghian F, et al. The Effects of Myrtle (Myrtus communis) and Clindamycin Topical Solution in the Treatment of Mild to Moderate Acne Vulgaris: A Comparative Split-Face Study. J Pharmacopuncture 2020;23(4):220-229.
  3. Paknejad MS, Eftekhari K, Rahimi R, Vigeh M, Naghizadeh A, Karimi M. Myrtle (Myrtus communis L.) fruit syrup for gastroesophageal reflux disease in children: A double-blind randomized clinical trial. Phytother Res 2021;35(11):6369-6376.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Myrtle and Mepolizumab Together: Common Questions

Is it safe to take Myrtle with Mepolizumab?
We do not list a known interaction between Myrtle and Mepolizumab. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Myrtle and Mepolizumab have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Myrtle monograph Uses, safety profile, and every drug interaction in one place Mepolizumab Injection drug information The full plain-English guide to this medication Mepolizumab supplement interactions Every supplement checked against Mepolizumab, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Mepolizumab and Myrtle?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.