Drug & supplement interaction

Oregon Fir Balsam + Probenecid

Probenecid brand names: Benemid, Benuryl, Probecid.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Oregon Fir Balsam and Probenecid in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Oregon Fir Balsam and Probenecid

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Probenecid and Oregon Fir Balsam in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Oregon Fir Balsam at all — not against Probenecid, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Oregon Fir Balsam safety at a glance

Oregon Fir Balsam overall Use caution Generally used topically and as a scent, but it can cause skin irritation or allergic reactions and lacks strong safety data for internal use.
Pregnancy Avoid Safety has not been established, so it is best to avoid medicinal or internal use during pregnancy.
Breastfeeding Avoid There is not enough information on safety while breastfeeding, so avoid medicinal use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Probenecid and Oregon Fir Balsam? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Probenecid’s Own FDA Label Lists

This is not an interaction — none of it involves Oregon Fir Balsam. These are the most notable effects listed in the ADVERSE REACTIONS section of Probenecid’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 6 of them are worth acting on rather than waiting out — marked below.

  • Anemia Worth acting on
  • A severe allergic reaction Worth acting on
  • Hives Worth acting on
  • A low white blood cell count Worth acting on
  • Liver problems Worth acting on
  • An allergic reaction Worth acting on
  • Flushing
  • Hair loss
  • Joint pain
  • Reduced appetite

Showing the 10 most notable of 17 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Probenecid. Read the label on DailyMed › Where a percentage is shown, it is the share of 1,262 voluntary FDA FAERS reports for Probenecid that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Oregon Fir Balsam’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Oregon Fir Balsam side to compare — that is a limit of the record, not a statement that Oregon Fir Balsam has no side effects.

From our Q&A

Questions About Oregon Fir Balsam or Probenecid

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Oregon Fir Balsam or Probenecid, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Probenecid

This page covers Oregon Fir Balsam only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Probenecid page lists 30 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Siberian Cocklebur (major), African Wild Potato (moderate) and Aristolochia (moderate).

By severity: 3 major · 17 moderate · 10 minor.

From our pharmacist’s overview on the Probenecid page

“Probenecid does its work through the kidneys, pulling uric acid out of the blood to control gout, and that is exactly why the 30 supplement and herbal interactions on file deserve genuine care rather than a quick skim. The three rated major strike where this drug is most vulnerable: two are herbs, Siberian cocklebur among them, that ca…”

Reviewed by 2 · Jul 18, 2026

Open the Probenecid interaction page

How much people look this up

Where Oregon Fir Balsam and Probenecid Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Oregon Fir Balsam
Steady interest

#1,448 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Probenecid
Top half

#1,051 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Oregon Fir Balsam is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Oregon Fir Balsam reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Oregon Fir Balsam and Probenecid records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Oregon Fir Balsam

What is Oregon Fir Balsam?

  • Minor cuts and skin wounds
  • Sore muscles and joints
  • Coughs and chest congestion
  • Antimicrobial skin applications
  • Aromatherapy and scenting products

Oregon Fir Balsam is a fragrant tree resin from fir species, traditionally used on the skin and in cough and aromatherapy products. There is very little high-quality human research to support its medical uses, and concentrated forms can irritate skin or cause allergic reactions, so use it cautiously and check with a pharmacist or doctor first.

Pinaceae · Oleoresin (pitch/balsam) from the fir tree, and sometimes the needles · Resin, salve or ointment, essential oil, tincture

An interaction check asks whether these two react with each other — it does not ask whether Oregon Fir Balsam is a good idea for someone in your situation. Here is what our Oregon Fir Balsam record says about it on its own.

Oregon Fir Balsam: dosing

There is no established standard dose for Oregon Fir Balsam. The right amount depends on the product and how it is used (for example, a salve versus a diluted essential oil).Follow the directions on the product label, and dilute essential oils properly before applying them to the skin.

From our Oregon Fir Balsam monograph — the full record covers uses, side effects and every documented interaction.

Read the full Oregon Fir Balsam monograph & all interactions
Medication

About Probenecid

What Is Probenecid Used For?

Brand names: Benemid, Benuryl, Probecid

Probenecid tablets are used to treat hyperuricemia (high uric acid levels in the blood) associated with gout and gouty arthritis. By helping the kidneys remove more uric acid, it lowers uric acid levels over time and helps prevent painful gout attacks.

Probenecid tablets are also used alongside certain penicillin-type antibiotics — including penicillin, ampicillin, methicillin, oxacillin, cloxacillin, and nafcillin — to raise and sustain the antibiotic's level in the bloodstream, making the antibiotic work more effectively.

See full Probenecid drug information
Keep checking

Other Drugs & Oregon Fir Balsam

Browse every other medication we’ve checked against Oregon Fir Balsam — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Oregon Fir Balsam References

The 3 sources that drive our Oregon Fir Balsam monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Oregon Fir Balsam is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbal Medicine — MedlinePlus Source
  3. Aromatherapy and Essential Oils — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Oregon Fir Balsam and Probenecid Together: Common Questions

Is it safe to take Oregon Fir Balsam with Probenecid?
We do not list a known interaction between Oregon Fir Balsam and Probenecid. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Probenecid interact with any supplements?
Yes. Probenecid has documented interactions with 30 supplements in our database — Oregon Fir Balsam is not one of them. The Probenecid interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Probenecid and Oregon Fir Balsam?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.