Para-aminobenzoic Acid (paba) + Bromocriptine
Bromocriptine brand name: Parlodel.
We found no known interaction between Para-aminobenzoic Acid (paba) and Bromocriptine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Bromocriptine states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Para-aminobenzoic Acid (paba) and Bromocriptine
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Bromocriptine and Para-aminobenzoic Acid (paba) in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Para-aminobenzoic Acid (paba) safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Bromocriptine
Interactions in our licensed database are recorded against drug classes, not just single drug names. Bromocriptine is filed under 4 classifications — including ergot derivatives, dopamine agonists, cytochrome p450 3a4 (cyp3a4) substrates. Para-aminobenzoic Acid (paba) has documented interactions with 2 drug classes — the most serious being dapsone (avlosulfon) (major) and sulfonamide antibiotics (major) — and none of Bromocriptine’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Para-aminobenzoic Acid (paba) Does Interact With Other Medications
Para-aminobenzoic Acid (paba) has 17 major, known drug interactions in our database — Bromocriptine isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Para-aminobenzoic Acid (paba)
We haven’t checked that one against Para-aminobenzoic Acid (paba) yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Para-aminobenzoic Acid (paba). Pick one to open its full report.
Para-aminobenzoic Acid (paba) in Pregnancy & Breastfeeding
When used topically and appropriately. There is insufficient reliable information available about the safety of the oral use of PABA during pregnancy and breast-feeding; avoid using.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
Some Bromocriptine Products Have a Food Rule — Para-aminobenzoic Acid (paba) Should Not Break It
At least one FDA label for a product containing Bromocriptine says to take it with food. If you take Para-aminobenzoic Acid (paba) on an empty stomach out of habit, keep them separate — and take Bromocriptine with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Bromocriptine products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
2 DOSAGE AND ADMINISTRATION Taken within two hours after waking in the morning with food ( 2.1 ) Initial dose is one tablet (0.8 mg) daily increased weekly by one tablet until maximal tolerated daily dose of 1.6 to 4.8 mg is achieved.
From the Dosage and Administration section of the FDA label we read for Bromocriptine — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
What Bromocriptine Is Prescribed For, and What Para-aminobenzoic Acid (paba) Has Been Studied For
These two come up together because they touch the same health topic — not because they do the same job. Bromocriptine is a prescription medicine with approved uses on its FDA label. Para-aminobenzoic Acid (paba) is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.
Bromocriptine is prescribed for: Bromocriptine mesylate tablets and capsules (sold as Parlodel and generics) treat conditions caused by too much prolactin in the blood — including missed periods, unwanted breast milk production, infertility, and hypogonadism (low sex-hormone function). They are also used for prolactin-secreting pituitary tumors (adenomas), acromegaly (excess growth hormone), and the signs and symptoms of Parkinson's disease, often alongside levodopa. Cycloset — a specific bromocriptine tablet formulation — is separately approved as an add-on to diet and exercise to improve blood sugar control in adults with type 2 diabetes. Cycloset should not be used for type 1 diabetes or diabetic ketoacidosis.
Para-aminobenzoic Acid (paba) has been studied for:
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Infertility studied, not established Para-aminobenzoic Acid (paba) has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Para-aminobenzoic Acid (paba) for infertility
Although there has been interest in using oral PABA for infertility, there is insufficient reliable information about the clinical effects of PABA for this purpose.
Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Bromocriptine on your own; if you are taking Para-aminobenzoic Acid (paba) for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.
See Every Supplement That Interacts With Bromocriptine
This page covers Para-aminobenzoic Acid (paba) only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Bromocriptine page lists 143 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).
By severity: 3 major · 99 moderate · 41 minor.
From our pharmacist’s overview on the Bromocriptine page
“Grapefruit is the supplement-aisle item I would flag first for anyone taking bromocriptine (Parlodel). It blocks CYP3A4, the enzyme that clears bromocriptine, so drug levels can climb and side effects with them.”
Reviewed by 2 · Jul 18, 2026
Where Para-aminobenzoic Acid (paba) and Bromocriptine Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,189 of 1,452 supplements looked up here in the last 7 days
#497 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Para-aminobenzoic Acid (paba) reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Para-aminobenzoic Acid (paba) and Bromocriptine records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Para-aminobenzoic Acid (paba)
What is Para-aminobenzoic Acid (paba)?
- Skin conditions like vitiligo
- Scleroderma and skin tightening conditions
- Graying hair
- Sunscreen ingredient (older topical products)
- General supplement and 'B-complex' support
PABA (para-aminobenzoic acid) is a chemical sometimes taken as a supplement or used in older sunscreens. Evidence supporting its oral use for skin conditions, hair color, and other claims is limited and outdated, and high doses can cause side effects. Talk with your pharmacist or doctor before using it.
Not a plant; PABA is a chemical compound (an amino acid-like substance) · Tablets, capsules, and topical creams or lotions
An interaction check asks whether these two react with each other — it does not ask whether Para-aminobenzoic Acid (paba) is a good idea for someone in your situation. Here is what our Para-aminobenzoic Acid (paba) record says about it on its own.
Para-aminobenzoic Acid (paba): dosing
There is no well-established standard dose of PABA for any condition, and high doses have been associated with toxicity. Some older studies used relatively large amounts under medical supervision, but these are not appropriate for routine self-treatment.If you choose to use a PABA product, follow the directions on the label and do not exceed the recommended amount.
From our Para-aminobenzoic Acid (paba) monograph — the full record covers uses, side effects and every documented interaction.
About Bromocriptine
What Is Bromocriptine Used For?
Brand name: Parlodel
Bromocriptine mesylate tablets and capsules (sold as Parlodel and generics) treat conditions caused by too much prolactin in the blood — including missed periods, unwanted breast milk production, infertility, and hypogonadism (low sex-hormone function). They are also used for prolactin-secreting pituitary tumors (adenomas), acromegaly (excess growth hormone), and the signs and symptoms of Parkinson's disease, often alongside levodopa.
Cycloset — a specific bromocriptine tablet formulation — is separately approved as an add-on to diet and exercise to improve blood sugar control in adults with type 2 diabetes. Cycloset should not be used for type 1 diabetes or diabetic ketoacidosis.
Other Drugs & Para-aminobenzoic Acid (paba)
Browse every other medication we’ve checked against Para-aminobenzoic Acid (paba) — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
17 interactions
- Dapsone ›
- Retapamulin ›
- Doripenem ›
- Sulfadiazine ›
- Sulfamethoxazole ›
- Sulfisoxazole ›
- Tigecycline ›
- Sulfamethoxazole, Trimethoprim ›
- Sulfadiazine, Sulfamerazine, Sulfamethazine ›
- Benazepril, Hydrochlorothiazide ›
- Enalapril Maleate, Hydrochlorothiazide ›
- Erythromycin Ethylsuccinate, Sulfisoxazole ›
- Erythromycin, Sulfisoxazole ›
- Fosinopril, Hydrochlorothiazide ›
- Hydrochlorothiazide, Moexipril ›
- Phenazopyridine, Sulfisoxazole ›
- Sulfadiazine, Trimethoprim ›
No interaction 2,812 drugs checked — show the list
We also checked Para-aminobenzoic Acid (paba) against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Acetaminophen ›
- Tadalafil ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Valacyclovir ›
- Abemaciclib ›
- Hydroxyurea ›
- Methamphetamine ›
- Ibuprofen ›
- Sumatriptan ›
- Semaglutide ›
- Warfarin Sodium ›
- Tirzepatide ›
- Prednisone ›
- Propranolol ›
- Bupropion ›
- Lisdexamfetamine ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Acyclovir ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Methotrexate ›
- Lamotrigine ›
- Fluoxetine ›
- Acetaminophen, Codeine ›
- Amphetamine ›
- Gabapentin ›
- Pregabalin ›
- Dextroamphetamine ›
- Azithromycin ›
- Isotretinoin ›
- Clonazepam ›
- Omeprazole ›
- Methylene Blue ›
- Quetiapine ›
- Amlodipine Besylate ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Naproxen ›
- Ciprofloxacin ›
Showing the 60 most looked-up of 2,812 medications checked with no known interaction — see the full Para-aminobenzoic Acid (paba) list.
Para-aminobenzoic Acid (paba) References
The 11 references that drive our Para-aminobenzoic Acid (paba) monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- United States Pharmacopeial Convention, Inc., ed. Drug Information for the Health Care Professional. 19th ed. Englewood, CO: Micromedex Inc., 1999.
- Facts and Comparisons staff. Drug Facts and Comparisons. St Louis: Wolters Kluwer Company (updated monthly).
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Worobec S, LaChine A. Dangers of orally administered para-aminobenzoic acid. JAMA 1984;251:2348. DOI
- Zarafonetis CJ, Dabich L, DeVol EB, et al. Potassium para-aminobenzoate and liver function test findings. J Am Acad Dermatol 1986;15:144-9. PubMed
- Clegg DO, Reading JC, Mayes MD, et al. Comparison of aminobenzoate potassium and placebo in the treatment of scleroderma. J Rheumatol 1994;21:105-10.
- Ludwig G. Evaluation of conservative therapeutic approaches to Peyronie's disease (fibrotic induration of the penis). Urol Int 1991;47:236-9. PubMed
- Kantor GR, Ratz JL. Liver toxicity from potassium para-aminobenzoate. J Am Acad Dermatol 1985;13:671-2. PubMed
- Wiesel LL, Barritt AS, Stumpe WM. The synergistic action of para-aminobenzoic acid and cortisone in the treatment of rheumatoid arthritis. Am J Med Sci 1951;243-8. DOI
- Taylor, S. E. and Dorris, R. L. Modification of local anesthetic toxicity by vasoconstrictors. Anesth.Prog 1989;36(3):79-87.
- Davies, D. M. and Cavanagh, J. Jaundice from potassium p-aminobenzoate. Lancet 4-22-1967;1(7495):896. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Para-aminobenzoic Acid (paba) and Bromocriptine Together: Common Questions
Is it safe to take Para-aminobenzoic Acid (paba) with Bromocriptine?
Do Para-aminobenzoic Acid (paba) and Bromocriptine have any of the same side effects?
Should I take Para-aminobenzoic Acid (paba) and Bromocriptine at the same time of day?
Are Para-aminobenzoic Acid (paba) and Bromocriptine used for the same thing?
How was the Para-aminobenzoic Acid (paba) and Bromocriptine combination checked?
Does Para-aminobenzoic Acid (paba) interact with any other medications?
Does Bromocriptine interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.