Para-aminobenzoic Acid (paba) - Dapsone Interaction Details

Interaction Details

Dapsone is classified as belonging to the following category: Dapsone (Avlosulfon)

Theoretically, concomitant use of PABA and dapsone may decrease the effects of dapsone.
Preliminary clinical research shows that PABA inhibits the antibacterial effects of dapsone. Avoid concurrent use.

Interaction Rating

Major

Likelihood of Occurrence

Likely

Well-controlled human studies have demonstrated the likely existence of this interaction

References

Facts and Comparisons staff. Drug Facts and Comparisons. St Louis: Wolters Kluwer Company (updated monthly).
Wiesel LL, Barritt AS, Stumpe WM. The synergistic action of para-aminobenzoic acid and cortisone in the treatment of rheumatoid arthritis. Am J Med Sci 1951;243-8.

Dapsone Overview

Dapsone is used to treat leprosy and skin infections.
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

See More Information Regarding Dapsone

Para-aminobenzoic Acid (paba) - More Interactions

Para-aminobenzoic Acid (paba) interacts with 17 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major	The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate	Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor	Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown	No interactions have been reported or no interaction data is currently available.